Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection impacted morbidity and mortality during the pandemic of 2020–2021. A number of anti-COVID-19 vaccines have been developed with an unprecedented speed. While these vaccines have good efficacy and are safe, the experience with their use is limited and hence the knowledge of rare side effects. Identifying rare… Continue reading Hepatitis #C Virus Reactivation Following #COVID-19 Vaccination – A Case Report
Fecal #microbiota transplantation from mice exposed to chronic intermittent hypoxia elicits #sleep disturbances in naïve mice
Obstructive sleep apnea (OSA) is a chronic prevalent condition characterized by intermittent hypoxia (IH) and sleep fragmentation (SF). Evidence suggests that OSA can alter the gut microbiome (GM) diversity and composition that may then promote the occurrence of some of the OSA-associated morbidities. However, it is unclear whether perturbations in the GM caused by IH… Continue reading Fecal #microbiota transplantation from mice exposed to chronic intermittent hypoxia elicits #sleep disturbances in naïve mice
Fasting plasma #glucose level in the range of 90 to 99 mg/dL and the risk of the onset of type 2 #diabetes: Population-based Panasonic cohort study 2
As the association between fasting glucose concentration from 90 to 99 mg/dL and the onset of type 2 diabetes is still controversial, we aimed to assess it in 37,148 Japanese individuals with normal plasma glucose concentration. Materials and MethodsThis long-term retrospective cohort study included individuals with medical checkup at Panasonic Corporation from 2008 to 2018.… Continue reading Fasting plasma #glucose level in the range of 90 to 99 mg/dL and the risk of the onset of type 2 #diabetes: Population-based Panasonic cohort study 2
Transmission of community- and hospital-acquired #SARS-CoV-2 in hospital settings in the UK: A cohort study
Nosocomial spread of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has been widely reported, but the transmission pathways among patients and healthcare workers (HCWs) are unclear. Identifying the risk factors and drivers for these nosocomial transmissions is critical for infection prevention and control interventions. The main aim of our study was to quantify the relative… Continue reading Transmission of community- and hospital-acquired #SARS-CoV-2 in hospital settings in the UK: A cohort study
Cardiac #radiotherapy induces electrical conduction reprogramming in the absence of transmural fibrosis
Cardiac radiotherapy (RT) may be effective in treating heart failure (HF) patients with refractory ventricular tachycardia (VT). The previously proposed mechanism of radiation-induced fibrosis does not explain the rapidity and magnitude with which VT reduction occurs clinically. Here, we demonstrate in hearts from RT patients that radiation does not achieve transmural fibrosis within the timeframe… Continue reading Cardiac #radiotherapy induces electrical conduction reprogramming in the absence of transmural fibrosis
Left #atrial strain predicts incident atrial #fibrillation in the general population: the Copenhagen City Heart Study
Left atrial (LA) strain parameters have been demonstrated to be valuable predictors of atrial fibrillation (AF) in several patient cohorts. The purpose of this study was to investigate whether LA strain, assessed by two-dimensional speckle-tracking echocardiography, can be used to predict the development of AF in the general population. Methods and resultsThis prospective longitudinal study… Continue reading Left #atrial strain predicts incident atrial #fibrillation in the general population: the Copenhagen City Heart Study
Could #glutathione depletion be the Trojan horse of #COVID-19 mortality?
Since the emergence of coronavirus disease (COVID-19), the death toll has been increasing daily. Many risk factors are associated with a high mortality rate in COVID-19. Establishment of a common pathway among these risk factors could improve our understanding of COVID-19 severity and mortality. This review aims at establishing this common pathway and its possible… Continue reading Could #glutathione depletion be the Trojan horse of #COVID-19 mortality?
Circuit-specific enteric #glia regulate #intestinal motor neurocircuits
Neurons have long been considered the main active cell type within the circuitry of the enteric nervous system (ENS), giving rise to a neurocentric paradigm that has tended to overlook the role of enteric glia as key regulators of gut motility. Understanding how simple synapse-level interactions give rise to complex, network-level behaviors remains a fundamental… Continue reading Circuit-specific enteric #glia regulate #intestinal motor neurocircuits
#Zinc, Vitamin D and Vitamin C: Perspectives for #COVID-19 With a Focus on Physical Tissue Barrier Integrity
Some nutrients play key roles in maintaining the integrity and function of the immune system, presenting synergistic actions in steps determinant for the immune response. Among these elements, zinc and vitamins C and D stand out for having immunomodulatory functions and for playing roles in preserving physical tissue barriers. Considering the COVID-19 pandemic, nutrients that… Continue reading #Zinc, Vitamin D and Vitamin C: Perspectives for #COVID-19 With a Focus on Physical Tissue Barrier Integrity
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