Dramatic increases in cannabis use during pregnancy are alarming because of evidence that prenatal exposure may be associated with a host of adverse outcomes. We previously found that prenatal cannabis exposure (PCE) following maternal knowledge of pregnancy is associated with increased psychopathology during middle childhood using baseline data from the Adolescent Brain Cognitive Development (ABCD) study.Here,… Continue reading Association of Mental Health Burden With Prenatal Cannabis Exposure From Childhood to Early AdolescenceLongitudinal Findings From the Adolescent Brain Cognitive Development (ABCD) Study
Understanding the Pharmacology of COVID-19 mRNA Vaccines: Playing Dice with the Spike?
AbstractCoronavirus disease-19 (COVID-19) mRNA vaccines are the mainstays of mass vaccination campaigns in most Western countries. However, the emergency conditions in which their development took place made it impossible to fully characterize their effects and mechanism of action. Here, we summarize and discuss available evidence indicating that COVID-19 mRNA vaccines better reflect pharmaceutical drugs than… Continue reading Understanding the Pharmacology of COVID-19 mRNA Vaccines: Playing Dice with the Spike?
Risk of Myocarditis After Sequential Doses of COVID-19 Vaccine and SARS-CoV-2 Infection by Age and Sex
AbstractBackground:Myocarditis is more common after severe acute respiratory syndrome coronavirus 2 infection than after COVID-19 vaccination, but the risks in younger people and after sequential vaccine doses are less certain.Methods:A self-controlled case series study of people ages 13 years or older vaccinated for COVID-19 in England between December 1, 2020, and December 15, 2021, evaluated… Continue reading Risk of Myocarditis After Sequential Doses of COVID-19 Vaccine and SARS-CoV-2 Infection by Age and Sex
Fitness tracking reveals task-specific associations between memory, mental health, and physical activity
Physical activity can benefit both physical and mental well-being. Different forms of exercise (e.g., aerobic versus anaerobic; running versus walking, swimming, or yoga; high-intensity interval training versus endurance workouts; etc.) impact physical fitness in different ways. For example, running may substantially impact leg and heart strength but only moderately impact arm strength. We hypothesized that… Continue reading Fitness tracking reveals task-specific associations between memory, mental health, and physical activity
Effects of cocoa extract and a multivitamin on cognitive function: A randomized clinical trial
IntroductionDietary supplements are touted for cognitive protection, but supporting evidence is mixed. COSMOS-Mind tested whether daily administration of cocoa extract (containing 500 mg/day flavanols) versus placebo and a commercial multivitamin-mineral (MVM) versus placebo improved cognition in older women and men.MethodsCOSMOS-Mind, a large randomized two-by-two factorial 3-year trial, assessed cognition by telephone at baseline and annually. The… Continue reading Effects of cocoa extract and a multivitamin on cognitive function: A randomized clinical trial
Periodontal health, cognitive decline, and dementia: A systematic review and meta-analysis of longitudinal studies
AbstractBackgroundEmerging evidence indicates that poor periodontal health adversely impacts cognition. This review examined the available longitudinal evidence concerning the effect of poor periodontal health on cognitive decline and dementia.MethodsComprehensive literature search was conducted on five electronic databases for relevant studies published until April 2022. Longitudinal studies having periodontal health as exposure and cognitive decline and/or… Continue reading Periodontal health, cognitive decline, and dementia: A systematic review and meta-analysis of longitudinal studies
Artificial sweeteners and risk of cardiovascular diseases: results from the prospective NutriNet-Santé cohort
Objectives To study the associations between artificial sweeteners from all dietary sources (beverages, but also table top sweeteners, dairy products, etc), overall and by molecule (aspartame, acesulfame potassium, and sucralose), and risk of cardiovascular diseases (overall, coronary heart disease, and cerebrovascular disease).Design Population based prospective cohort study (2009-21).Setting France, primary prevention research.Participants 103 388 participants of the web based NutriNet-Santé… Continue reading Artificial sweeteners and risk of cardiovascular diseases: results from the prospective NutriNet-Santé cohort
Role of scientific advice in covid-19 policy
Key messageGovernments claimed to be following scientific advice during the pandemic to legitimise decisionsAdvice should be autonomous to ensure that governments do not simply seek advice that aligns with what they want to hearTransparency is also essential to know who gave the advice and what the government did with itThe UK’s advice system was not… Continue reading Role of scientific advice in covid-19 policy
How nature nurtures: Amygdala activity decreases as the result of a one-hour walk in nature
Since living in cities is associated with an increased risk for mental disorders such as anxiety disorders, depression, and schizophrenia, it is essential to understand how exposure to urban and natural environments affects mental health and the brain. It has been shown that the amygdala is more activated during a stress task in urban compared… Continue reading How nature nurtures: Amygdala activity decreases as the result of a one-hour walk in nature
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