BackgroundNutritional strategies for prevention and management of type 2 diabetes traditionally emphasize dietary patterns reflecting nutrient goals, but the health implications of ultra-processed food (UPF) for patients with type 2 diabetes remain unknown.ObjectiveTo evaluate the association of UPF intake with all-cause and cardiovascular disease (CVD) mortality amongst participants with type 2 diabetes from the Moli-sani… Continue reading #Ultra-processed #food consumption is associated with all-cause and #cardiovascular mortality in participants with type 2 #diabetes independent of diet quality: a prospective observational cohort study
Category: Diet
#Espresso Coffee Mitigates the Aggregation and Condensation of #Alzheimer′s Associated Tau Protein
Espresso coffee is among the most consumed beverages in the world. Recent studies report a protective activity of the coffee beverage against neurodegenerative disorders such as Alzheimer′s disease. Alzheimer′s disease belongs to a group of disorders, called tauopathies, which are characterized by the intraneuronal accumulation of the microtubule-associated protein tau in fibrillar aggregates. In this… Continue reading #Espresso Coffee Mitigates the Aggregation and Condensation of #Alzheimer′s Associated Tau Protein
Vegetarian Dietary Patterns and Cardiometabolic Risk in People With or at High Risk of Cardiovascular DiseaseA Systematic Review and Meta-analysis
MPORTANCE Plant-based diets are known to improve cardiometabolic risk in the general population, but their effects on people at high risk of cardiovascular diseases (CVDs) remain inconclusive.OBJECTIVE To assess the association of vegetarian diets with major cardiometabolic risk factors,including low-density lipoprotein cholesterol (LDL-C), hemoglobin A1c (HbA1c), systolic blood pressure (SBP), and body weight in people… Continue reading Vegetarian Dietary Patterns and Cardiometabolic Risk in People With or at High Risk of Cardiovascular DiseaseA Systematic Review and Meta-analysis
Opting for olive oil could boost brain healthRegular olive oil consumption associated with 28% lower risk of fatal dementia
oil as part of a Mediterranean dietary pattern has also been shown to help protect against cognitive decline. Tessier cautioned that the research is observational and does not prove that olive oil is the cause of the reduced risk of fatal dementia. Additional studies such as randomized controlled trials would be needed to confirm the effects… Continue reading Opting for olive oil could boost brain healthRegular olive oil consumption associated with 28% lower risk of fatal dementia
Vitamin D status & associations with inflammation in older adults
Research studies have observed associations of vitamin D with inflammation but data in representative older adult studies is lacking. We aimed to investigate the association of C-reactive protein (CRP) with vitamin D status in a representative sample of the older Irish population. The concentrations of 25-hydroxyvitamin D (25(OH)D) and CRP was measured in 5,381 community… Continue reading Vitamin D status & associations with inflammation in older adults
Excess Dietary Sugar Alters Colonocyte Metabolism and Impairs the Proliferative Response to Damage
The colonic epithelium requires continuous renewal by crypt resident intestinal stem cells (ISCs) and transit-amplifying (TA) cells to maintain barrier integrity, especially after inflammatory damage. The diet of high-income countries contains increasing amounts of sugar, such as sucrose. ISCs and TA cells are sensitive to dietary metabolites, but whether excess sugar affects their function directly… Continue reading Excess Dietary Sugar Alters Colonocyte Metabolism and Impairs the Proliferative Response to Damage
Infused juice concentrate of Japanese plum Prunus mume attenuates inflammatory vascular remodeling in a mouse model of hypertension induced by angiotensin II
Fruit from the Prunus mume tree is a traditional food in Japan. Recently, bainiku-ekisu, an infused juice concentrate of Japanese Prunus mume, is attracting attention as a health promoting supplement. Angiotensin II (Ang II) plays a central role in development of hypertension. It has been reported that bainiku-ekisu treatment attenuates the growth-promoting signaling induced by Ang II in… Continue reading Infused juice concentrate of Japanese plum Prunus mume attenuates inflammatory vascular remodeling in a mouse model of hypertension induced by angiotensin II
A history of repeated alcohol intoxication promotes cognitive impairment and gene expression signatures of disease progression in the 3xTg mouse model of Alzheimer’s disease
The impact of alcohol abuse on Alzheimer’s disease (AD) is poorly understood. Here, we show that the onset of neurocognitive impairment in a mouse model of AD is hastened by repeated alcohol intoxication through exposure to alcohol vapor, and we provide a comprehensive gene expression dataset of the prefrontal cortex by the single-nucleus RNA sequencing… Continue reading A history of repeated alcohol intoxication promotes cognitive impairment and gene expression signatures of disease progression in the 3xTg mouse model of Alzheimer’s disease
Can Circadian Eating Pattern Adjustments Reduce Risk or Prevent Development of T2D?
Type 2 diabetes (T2D) is a chronic condition that occurs in insulin-resistant people with reduced glucose uptake. It is contributed to and exacerbated by a poor diet that results in accumulation of adipose tissue, high blood sugar, and other metabolic issues. Because humans have undergone food scarcity throughout history, our species has adapted a fat… Continue reading Can Circadian Eating Pattern Adjustments Reduce Risk or Prevent Development of T2D?
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