Nut consumption may reduce age-related cognitive decline, but underlying mechanisms are unclear ObjectiveTo investigate in older adults longer-term effects of mixed nut consumption on brain vascular function, which may underlie improvements in cognitive performance.MethodsTwenty-eight healthy individuals (age [mean ± SD]: 65 ± 3 years; BMI: 27.9 ± 2.3 kg/m2) were included in a randomized, single-blinded, cross-over trial with a 16-week intervention (60 g/d… Continue reading Longer-term mixed nut consumption improves brain vascular function and memory: A randomized, controlled crossover trial in older adults
Category: Diet
Semaglutide reduces alcohol intake and relapse-like drinking in male and female rats
BackgroundGlucagon-like peptide1 receptor (GLP-1R) agonists have been found to reduce alcohol drinking in rodents and overweight patients with alcohol use disorder (AUD). However, the probability of low semaglutide doses, an agonist with higher potency and affinity for GLP-1R, to attenuate alcohol-related responses in rodents and the underlying neuronal mechanisms is unknown.MethodsIn the intermittent access model,… Continue reading Semaglutide reduces alcohol intake and relapse-like drinking in male and female rats
Impact of a Low-Carbohydrate Compared with Low-Fat Breakfast on Blood Glucose Control in Type 2 Diabetes: A Randomized Trial
BackgroundIn type 2 diabetes (T2D), consuming carbohydrates results in a rapid and large increase in blood glucose, particularly in the morning when glucose intolerance is highest.ObjectivesWe investigated if a low-carbohydrate (LC) breakfast (∼465 kcal: 25 g protein, 8 g carbohydrates, and 37 g fat) could improve glucose control in people with T2D when compared with a low-fat control (CTL) breakfast (∼450… Continue reading Impact of a Low-Carbohydrate Compared with Low-Fat Breakfast on Blood Glucose Control in Type 2 Diabetes: A Randomized Trial
A comparison of the nutritional profile and nutrient density of commercially available plant-based and dairy yogurts in the United States
Plant-based yogurts are sustainable alternatives to dairy yogurts, but a nutritional comparison of plant-based yogurts within the context of dairy yogurts has not yet been applied to commercially available products in the United States. Dairy yogurts provide significant dietary nutrients, and substituting plant-based yogurts may have unintended nutritional consequences. The objective of this study was… Continue reading A comparison of the nutritional profile and nutrient density of commercially available plant-based and dairy yogurts in the United States
Moderate protein intake percentage in mice for maintaining metabolic health during approach to old age
Nutritional requirements for maintaining metabolic health may vary with each life stage, such as young, middle, and old age. To investigate the appropriate ratio of nutrients, particularly proteins, for maintaining metabolic health while approaching old age, young (6-month-old) and middle-aged (16-month-old) mice were fed isocaloric diets with varying protein percentages (5%, 15%, 25%, 35%, and… Continue reading Moderate protein intake percentage in mice for maintaining metabolic health during approach to old age
Dietary flavanols restore hippocampal-dependent memory in older adults with lower diet quality and habitual flavanol consumption
Dietary flavanols are food constituents found in certain fruits and vegetables that have been linked to cognitive aging. Previous studies suggested that consumption of dietary flavanols might specifically be linked to the hippocampal-dependent memory component of cognitive aging and that memory benefits of a flavanol intervention might depend on habitual diet quality. Here, we tested… Continue reading Dietary flavanols restore hippocampal-dependent memory in older adults with lower diet quality and habitual flavanol consumption
Excess dietary sugar alters colonocyte metabolism and impairs the proliferative response to damage
BackgroundThe colonic epithelium requires continuous renewal by crypt resident intestinal stem cells (ISCs) and transit amplifying (TA) cells to maintain barrier integrity, especially after inflammatory damage. The diet of high-income countries contains increasing amounts of sugar, such as sucrose. ISCs and TA cells are sensitive to dietary metabolites, but whether excess sugar affects their function… Continue reading Excess dietary sugar alters colonocyte metabolism and impairs the proliferative response to damage
Higher intake of dietary flavonols, specifically dietary quercetin, is associated with lower odds of frailty onset over 12 years of follow-up among adults in the Framingham Heart Study
BackgroundPolyphenolic antioxidants derived from plant foods may reduce oxidative stress and frailty, but the effect of the polyphenol subclass of dietary flavonoids and their subclasses on frailty is uncertain.ObjectivesTo determine the association between dietary flavonoids, their subclasses, quercetin (a specific flavonol), and frailty onset in adults.MethodsThis prospective cohort study included individuals from the Framingham Heart… Continue reading Higher intake of dietary flavonols, specifically dietary quercetin, is associated with lower odds of frailty onset over 12 years of follow-up among adults in the Framingham Heart Study
Imagined eating – An investigation of priming and sensory-specific satiety
While obesity remains a pressing issue, the wider population continues to be exposed to more digital food content than ever before. Much research has demonstrated the priming effect of visual food content, i.e., exposure to food cues increasing appetite and food intake. In contrast, some recent research points out that repeated imagined consumption can facilitate… Continue reading Imagined eating – An investigation of priming and sensory-specific satiety
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