We previously reported that treatment of mice with 6-gingerol, the most abundant phytochemical in ginger root, leads to phosphodiesterase inhibition that counteracts neutrophil hyperactivity in models of antiphospholipid syndrome (APS) and lupus. Here, we explored the extent to which oral intake of a whole-ginger extract would similarly impact neutrophils in both autoimmune mice and healthy… Continue reading #Ginger intake suppresses neutrophil extracellular trap formation in #autoimmune mice and healthy humans
Category: Diet
Dietary Patterns, Foods, and #Nutrients to Ameliorate Non-Alcoholic #Fatty Liver Disease: A Scoping Review
Background: Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease without pharmacological treatment yet. There is also a lack of specific dietary recommendations and strategies to treat the negative health impacts derived from NAFLD. Objective: This scoping review aimed to compile dietary patterns, foods, and nutrients to ameliorate NAFLD. Methods:… Continue reading Dietary Patterns, Foods, and #Nutrients to Ameliorate Non-Alcoholic #Fatty Liver Disease: A Scoping Review
#Almonds vs. #carbohydrate snacks in an energy-restricted diet: Weight and cardiometabolic outcomes from a randomized trial
ObjectiveThis study evaluated weight and cardiometabolic outcomes after a 3-month energy-restricted diet (−30%) containing almonds (almond-enriched diet [AED]) or containing carbohydrate-rich snacks (nut-free control diet [NFD]) (Phase 1), followed by 6 months of weight maintenance (Phase 2).MethodsParticipants (25–65 years old) with overweight or obesity (BMI 27.5–34.9 kg/m2) were randomly allocated to AED (n = 68) or NFD (n = 72).ResultsBoth groups lost weight… Continue reading #Almonds vs. #carbohydrate snacks in an energy-restricted diet: Weight and cardiometabolic outcomes from a randomized trial
Dietary #Carbohydrate and #Fat Intakes and Risk of Mortality in the Japanese Population: the Japan Multi-Institutional Collaborative Cohort Study
BackgroundPrevious cohort studies have yielded contradictory findings regarding the associations of dietary carbohydrate and fat intakes with risks of mortality.ObjectivesWe examined long-term associations of carbohydrate and fat intakes with mortality.MethodsIn this cohort study, 34,893 men and 46,440 women aged 35–69 y (mean body mass index of 23.7 and 22.2 kg/m2, respectively) were followed up from the baseline survey (2004–2014)… Continue reading Dietary #Carbohydrate and #Fat Intakes and Risk of Mortality in the Japanese Population: the Japan Multi-Institutional Collaborative Cohort Study
Dietary #Carbohydrate and #Fat Intakes and Risk of #Mortality in the Japanese Population: the Japan Multi-Institutional Collaborative Cohort Study
BackgroundPrevious cohort studies have yielded contradictory findings regarding the associations of dietary carbohydrate and fat intakes with risks of mortality.ObjectivesWe examined long-term associations of carbohydrate and fat intakes with mortality.MethodsIn this cohort study, 34,893 men and 46,440 women aged 35–69 y (mean body mass index of 23.7 and 22.2 kg/m2, respectively) were followed up from the baseline survey (2004–2014)… Continue reading Dietary #Carbohydrate and #Fat Intakes and Risk of #Mortality in the Japanese Population: the Japan Multi-Institutional Collaborative Cohort Study
High #ultra-processed food consumption is associated with elevated #psychological distress as an indicator of #depression in adults from the Melbourne Collaborative Cohort Study
Highlights•Participants with the highest intake of ultra-processed food had increased odds of elevated psychological distress•We found no evidence for an interaction of sex, age and body mass index with ultra-processed food intake•Further research is needed to better inform nutrition-related and public health strategies for mental health BackgroundFew studies have tested longitudinal associations between ultra-processed food… Continue reading High #ultra-processed food consumption is associated with elevated #psychological distress as an indicator of #depression in adults from the Melbourne Collaborative Cohort Study
Dietary wheat #gluten induces astro- and #microgliosis in the hypothalamus of male mice
Gluten, which is found in cereals such as wheat, rye and barley, makes up a major dietary component in most western nations, and has been shown to promote body mass gain and peripheral inflammation in mice. In the current study, we investigated the impact of gluten on central inflammation that is typically associated with diet-induced… Continue reading Dietary wheat #gluten induces astro- and #microgliosis in the hypothalamus of male mice
The #fructose survival hypothesis for #obesity
The fructose survival hypothesis proposes that obesity and metabolic disorders may have developed from over-stimulation of an evolutionary-based biologic response (survival switch) that aims to protect animals in advance of crisis. The response is characterized by hunger, thirst, foraging, weight gain, fat accumulation, insulin resistance, systemic inflammation and increased blood pressure. The process is initiated by the… Continue reading The #fructose survival hypothesis for #obesity
Association between added #sugars and kidney #stones in U.S. adults: data from National Health and Nutrition Examination Survey 2007–2018
Added sugar is associated with a variety of adverse health outcomes, but its association with kidney stones is unclear. This study was to determine whether added sugar is associated with kidney stones.Materials and methods: This nationally representative study used National Health and Nutrition Examination Survey (NHANES) datasets from 2007 to 2018 for analysis. People aged ≥20 years… Continue reading Association between added #sugars and kidney #stones in U.S. adults: data from National Health and Nutrition Examination Survey 2007–2018
