Changes in atrial #fibrillation admissions following #daylight saving time transitions

Daylight saving time (DST) imposes a twice-yearly hour shift. The transitions to and from DST are associated with decreases in sleep quality and environmental hazards. Detrimental health effects include increased incidence of acute myocardial infarction (MI) following the springtime transition and increased ischemic stroke following both DST transitions. Conditions effecting sleep are known to provoke… Continue reading Changes in atrial #fibrillation admissions following #daylight saving time transitions

Clinical Effectiveness and Safety of #Aspirin for Venous #Thromboembolism Prophylaxis After Total Hip and Knee Replacement

Patients undergoing total hip replacement (THR) and total knee replacement (TKR) receive venous thromboembolism (VTE) pharmacoprophylaxis. It is unclear which anticoagulant is preferable. Observational data suggest aspirin provides effective VTE prophylaxis.. ..The RR of VTE after THR and TKR was 1.12 (95% CI, 0.78-1.62) for aspirin compared with other anticoagulants. Comparable findings were observed for… Continue reading Clinical Effectiveness and Safety of #Aspirin for Venous #Thromboembolism Prophylaxis After Total Hip and Knee Replacement

Olive Oil Consumption and Cardiovascular Risk in U.S. Adults

Olive oil intake has been associated with lower risk of cardiovascular disease (CVD) in Mediterranean populations, but little is known about these associations in the U.S population. ..During 24 years of follow-up, we documented 9,797 incident cases of CVD, including 6,034 CHD cases and 3,802 stroke cases. After adjusting for major diet and lifestyle factors,… Continue reading Olive Oil Consumption and Cardiovascular Risk in U.S. Adults

#Beverage Consumption and Longitudinal Changes in Lipoprotein Concentrations and Incident #Dyslipidemia in US Adults: The Framingham Heart Study

Limited data are available on the prospective relationship between beverage consumption and plasma lipid and lipoprotein concentrations. Two major sources of sugar in the US diet are sugar‐sweetened beverages (SSBs) and 100% fruit juices. Low‐calorie sweetened beverages are common replacements.. ..We found that regular (>1 serving per day) versus low (<1 serving per month) SSB… Continue reading #Beverage Consumption and Longitudinal Changes in Lipoprotein Concentrations and Incident #Dyslipidemia in US Adults: The Framingham Heart Study

Total #Sitting Time and Sitting Pattern in Postmenopausal Women Differ by Hispanic Ethnicity and are Associated With #Cardiometabolic Risk Biomarkers

Sedentary behavior is pervasive, especially in older adults, and is associated with cardiometabolic disease and mortality. Relationships between cardiometabolic biomarkers and sitting time are unexplored in older women, as are possible ethnic differences.. ..Hispanic women sat, on average, 50.3 minutes less/day than non‐Hispanic women (P<0.001) and had shorter (3.6 minutes less, P=0.02) mean sitting bout… Continue reading Total #Sitting Time and Sitting Pattern in Postmenopausal Women Differ by Hispanic Ethnicity and are Associated With #Cardiometabolic Risk Biomarkers

Evaluation of a Common Prescribing Cascade of Calcium Channel Blockers and Diuretics in Older Adults With #Hypertension

Calcium channel blockers (CCBs) are commonly prescribed agents for hypertension that can cause peripheral edema. A prescribing cascade occurs when the edema is misinterpreted as a new medical condition and a diuretic is subsequently prescribed to treat the edema. The extent to which this prescribing cascade occurs at a population level is not well understood..… Continue reading Evaluation of a Common Prescribing Cascade of Calcium Channel Blockers and Diuretics in Older Adults With #Hypertension

Clinical Implications of the New York Heart Association Classification

The New York Heart Association (NYHA) classification has served as a fundamental tool for risk stratification of heart failure (HF) and determines clinical trial eligibility and candidacy for drugs and devices. However, its ability to adequately stratify risk is unclear.. Cumulative mortality varied significantly across NYHA classes and HF clinical trials (likelihood ratio, P<0.001). Mortality… Continue reading Clinical Implications of the New York Heart Association Classification

The intestinal #microbiota and #cardiovascular disease

The intestinal microbiota of human hosts is the community of microorganisms living in the small and, mainly, the large intestine of humans. This microbial ecosystem has co-evolved with humans across the millennia, has come to play an important interactive role in human physiology and has been aptly called our forgotten organ. Significant properties of the… Continue reading The intestinal #microbiota and #cardiovascular disease

Red #blood cell dysfunction: a new player in #cardiovascular disease

The primary role of red blood cells (RBCs) is to transport oxygen to the tissues and carbon dioxide to the lungs. However, emerging evidence suggests an important role of the RBC beyond being just a passive carrier of the respiratory gases. The RBCs are of importance for redox balance and are actively involved in the… Continue reading Red #blood cell dysfunction: a new player in #cardiovascular disease