Sex Differences in Blood #Pressure Trajectories Over the Life Course

..Women compared with men exhibited a steeper increase in BP that began as early as in the third decade and continued through the life course (likelihood ratio test χ2 = 531 for systolic BP; χ2 = 123 for diastolic BP; χ2 = 325 for MAP; and χ2 = 572 for PP; P for all <.001). After adjustment for multiple cardiovascular disease risk factors,… Continue reading Sex Differences in Blood #Pressure Trajectories Over the Life Course

Associations between Serum Levels of #Cholesterol and #survival to Age 90 in Postmenopausal Women

Although elevated lipid levels predict increased risk of coronary heart disease and death in middle‐aged women and men, evidence is mixed if lipid levels measured in later life predict survival to very old ages.. HDL and LDL levels were not associated with survival to age 90 after adjustment for cardiovascular risk factors.. Similarly, no associations… Continue reading Associations between Serum Levels of #Cholesterol and #survival to Age 90 in Postmenopausal Women

Estimated #Stroke-Free Survival of #Folic Acid Therapy for Hypertensive Adults

The CSPPT (China Stroke Primary Prevention Trial) demonstrated a significant risk reduction of first stroke in hypertensive patients treated with enalapril plus folic acid compared with those with enalapril alone, but the lifetime stroke-free survival associated with the treatment is unknown.. ..Compared with enalapril alone, the enalapril plus folic acid treatment projected a mean lifetime… Continue reading Estimated #Stroke-Free Survival of #Folic Acid Therapy for Hypertensive Adults

Shared Genetic Loci Between Body #Mass Index and Major #Psychiatric Disorders A Genome-wide Association Study

People with major psychiatric disorders (MPDs) have a 10- to 20-year shorter life span than the rest of the population, and this difference is mainly due to comorbid cardiovascular diseases.. schizophrenia (SCZ), bipolar disorder (BIP), major depression (MD) body mass index (BMI) ..Of the shared loci, 34% (73 of 213) in SCZ, 52% (36 of… Continue reading Shared Genetic Loci Between Body #Mass Index and Major #Psychiatric Disorders A Genome-wide Association Study

Intensive vs Standard Blood #Pressure Control in Adults 80 Years or Older: A Secondary Analysis of the #Systolic Blood Pressure Intervention Trial

Participants with hypertension but without diabetes (N = 1167) were randomized to an SBP target below 120 mm Hg (intensive treatment) vs a target below 140 mm Hg (standard treatment).. Intensive treatment led to significant reductions in cardiovascular events (hazard ratio [HR] = .66; 95% confidence interval [CI] = .49‐.90), mortality (HR = .67; 95% CI =… Continue reading Intensive vs Standard Blood #Pressure Control in Adults 80 Years or Older: A Secondary Analysis of the #Systolic Blood Pressure Intervention Trial

#Tea consumption and the risk of atherosclerotic #cardiovascular disease and all-cause mortality: The China-PAR project

..Compared with never or non-habitual tea drinkers, the hazard ratio and 95% confidence interval among habitual tea drinkers was 0.80 (0.75–0.87), 0.78 (0.69–0.88), and 0.85 (0.79–0.90) for atherosclerotic cardiovascular disease incidence, atherosclerotic cardiovascular disease mortality, and all-cause mortality, respectively. Habitual tea drinkers had 1.41 years longer of atherosclerotic cardiovascular disease-free years and 1.26 years longer… Continue reading #Tea consumption and the risk of atherosclerotic #cardiovascular disease and all-cause mortality: The China-PAR project

Healthy #lifestyle and life #expectancy free of cancer, cardiovascular disease, and type 2 diabetes: prospective cohort study

..Five low risk lifestyle factors: never smoking, body mass index 18.5-24.9, moderate to vigorous physical activity (≥30 minutes/day), moderate alcohol intake (women: 5-15 g/day; men 5-30 g/day), and a higher diet quality score (upper 40%). .. The life expectancy free of diabetes, cardiovascular diseases, and cancer at age 50 was 23.7 years (95% confidence interval… Continue reading Healthy #lifestyle and life #expectancy free of cancer, cardiovascular disease, and type 2 diabetes: prospective cohort study

Relation of Total #Sugars, Sucrose, Fructose, and Added Sugars With the Risk of #Cardiovascular Disease

..Total sugars, sucrose, and fructose were not associated with CVD incidence. Total sugars (risk ratio, 1.09 [95% confidence interval, 1.02 to 1.17]) and fructose (1.08 [1.01 to 1.15]) showed a harmful association for CVD mortality, there was no association for added sugars and a beneficial association for sucrose (0.94 [0.89 to 0.99]). Dose-response analyses showed… Continue reading Relation of Total #Sugars, Sucrose, Fructose, and Added Sugars With the Risk of #Cardiovascular Disease

Association between ambient fine #particulate pollution and hospital admissions for cause specific #cardiovascular disease: time series study in 184 major Chinese cities

..At the national average level, an increase of 10 μg/m3 in PM2.5 was associated with a 0.26% (95% confidence interval 0.17% to 0.35%) increase in hospital admissions on the same day for cardiovascular disease, 0.31% (0.22% to 0.40%) for ischaemic heart disease, 0.27% (0.04% to 0.51%) for heart failure, 0.29% (0.12% to 0.46%) for heart… Continue reading Association between ambient fine #particulate pollution and hospital admissions for cause specific #cardiovascular disease: time series study in 184 major Chinese cities