..Four baseline lifestyle factors (smoking, body mass index, physical activity, and alcohol consumption) were each allocated a score based on risk status: optimal (2 points), intermediate (1 point), or poor (0 points) resulting in an aggregated lifestyle score ranging from 0 (worst) to 8 (best). Sixteen lifestyle profiles were constructed from combinations of these risk… Continue reading Association of Healthy #Lifestyle With Years Lived Without Major Chronic Diseases
Category: Cardiology
#Coronary Artery Calcium for Personalized Allocation of #Aspirin in Primary Prevention of Cardiovascular Disease in 2019: The Multi-Ethnic Study of Atherosclerosis (MESA)
..The present study aimed to assess the value of coronary artery calcium (CAC) for guiding aspirin allocation for primary prevention using 2019 aspirin meta-analysis data on CVD relative risk reduction (RRR) and bleeding risk ..Only 5% of MESA participants would qualify for aspirin consideration for primary prevention according to ACC/AHA guidelines and using >20% estimated… Continue reading #Coronary Artery Calcium for Personalized Allocation of #Aspirin in Primary Prevention of Cardiovascular Disease in 2019: The Multi-Ethnic Study of Atherosclerosis (MESA)
Cardiac #Autoimmunity Is Associated With Subclinical Myocardial Dysfunction in Patients With Type 1 #Diabetes Mellitus
The existence of a diabetic cardiomyopathy has been postulated to explain the increased risk of heart failure (HF) in patients with diabetes mellitus; however, whether mechanisms specific to type 1 diabetes mellitus (T1DM) affect the myocardium is unclear. We have recently shown that poor glycemic control in patients with T1DM followed in the DCCT (Diabetes… Continue reading Cardiac #Autoimmunity Is Associated With Subclinical Myocardial Dysfunction in Patients With Type 1 #Diabetes Mellitus
Potential Effects of #Coronaviruses on the #Cardiovascular System
Coronavirus disease 2019 can cause a viral pneumonia with additional extrapulmonary manifestations and complications. A large proportion of patients have underlying cardiovascular disease and/or cardiac risk factors. Factors associated with mortality include male sex, advanced age, and presence of comorbidities including hypertension, diabetes mellitus, cardiovascular diseases, and cerebrovascular diseases. Acute cardiac injury determined by elevated… Continue reading Potential Effects of #Coronaviruses on the #Cardiovascular System
EMA advises continued use of medicines for #hypertension, heart or #kidney disease during COVID-19 pandemic
EMA is aware of recent media reports and publications which question whether some medicines, for instance angiotensin converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs, or sartan medicines), could worsen coronavirus disease (COVID-19). ACE inhibitors and ARBs are most commonly used for treating patients with high blood pressure, heart failure or kidney disease. It… Continue reading EMA advises continued use of medicines for #hypertension, heart or #kidney disease during COVID-19 pandemic
#Aspirin for primary prevention of cardiovascular disease, part 2
..ASPREE study suggests no benefit from aspirin in primary prevention ASPREE randomized 19,114 healthy people 70 or over (65 or over for African Americans and Hispanics) to receive either 100 milligrams of enteric-coated aspirin or placebo. After an average of almost five years, there was no significant difference in the rate of fatal coronary heart… Continue reading #Aspirin for primary prevention of cardiovascular disease, part 2
Open Access Oral #glucocorticoids and incidence of #hypertension in people with chronic inflammatory diseases: a population-based cohort study
..Among 71 642 patients in the cohort, 24 896 (34.8%) developed hypertension during a median follow-up of 6.6 years. The incidence rate of hypertension was 46.7 (95% confidence interval [CI] 46.0–47.3) per 1000 person-years. Incidence rates increased with higher cumulative glucocorticoid prednisolone-equivalent dose, from 44.4 per 1000 person-years in periods of nonuse to 45.3 per… Continue reading Open Access Oral #glucocorticoids and incidence of #hypertension in people with chronic inflammatory diseases: a population-based cohort study
Blood #pressure in frail older adults: associations with #cardiovascular outcomes and all-cause mortality
Blood pressure (BP) management in frail older people is challenging. An randomised controlled trial of largely non-frail older people found cardiovascular and mortality benefit with systolic (S) BP target <120 mmHg. However, all-cause mortality by attained BP in routine care in frail adults aged above 75 is unclear.. ..Risks of cardiovascular outcomes increased with SBPs… Continue reading Blood #pressure in frail older adults: associations with #cardiovascular outcomes and all-cause mortality
Effectiveness and Safety of #Apixaban Compared With #Rivaroxaban for Patients With Atrial Fibrillation in Routine Practice: A Cohort Study
Apixaban and rivaroxaban are the most commonly prescribed direct oral anticoagulants for adults with atrial fibrillation, but head-to-head data comparing their safety and effectiveness are lacking.. 39 351 patients newly prescribed apixaban were propensity score matched to 39 351 patients newly prescribed rivaroxaban. Mean age was 69 years, 40% of patients were women, and mean… Continue reading Effectiveness and Safety of #Apixaban Compared With #Rivaroxaban for Patients With Atrial Fibrillation in Routine Practice: A Cohort Study
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