Background: Studies show variable results on health outcomes of isolated diastolic hypertension (IDH); however, data are scarce on its association with early kidney injury.Methods: We analyzed the Korea National Health and Nutrition Examination Survey data (2011-2014 and 2019-2024) in adults ≥19 years. After excluding those taking antihypertensive medication or with established kidney disease, participants were… Continue reading Association of isolated systolic and diastolic hypertension with moderately increased albuminuria: the Korea National Health and Nutrition Examination Survey
Category: Cardiology
The Incretin Revolution: Integrating Incretin-Based Therapies into Clinical Care
Incretin-based therapies have changed the landscape of modern medical practice. Obesity-related disease processes including type 2 diabetes mellitus, cardiovascular disease, chronic kidney disease, metabolic dysfunction-associated steatotic liver disease, and obstructive sleep apnea improve in patients treated with these medications, and several now carry organ-specific regulatory indications. In this narrative review we summarize the mechanisms through… Continue reading The Incretin Revolution: Integrating Incretin-Based Therapies into Clinical Care
Ultrashort vs Standard-Duration Dual Antiplatelet Therapy in Acute Coronary Syndrome Patients Undergoing PCI: A Meta-Analysis
Background: The efficacy and safety of ultrashort (≤1-month) dual antiplatelet therapy (DAPT) followed by antiplatelet monotherapy remain uncertain in acute coronary syndrome (ACS) patients.Objectives: This study sought to compare ultrashort vs standard-duration DAPT in patients with ACS undergoing percutaneous coronary intervention (PCI).Methods: We conducted a systematic review and meta-analysis of randomized controlled trials until February… Continue reading Ultrashort vs Standard-Duration Dual Antiplatelet Therapy in Acute Coronary Syndrome Patients Undergoing PCI: A Meta-Analysis
Mechanical complications of transcatheter aortic valve replacement: a review article
Aortic stenosis (AS) represents a prevalent valvular heart disease, particularly affecting the elderly population, with substantial implications for morbidity and mortality. This review examines the epidemiology, pathophysiology, management strategies, complications, and future implications of AS and its treatment modalities, focusing primarily on transcatheter aortic valve replacement (TAVR). The prevalence of AS is rising as the… Continue reading Mechanical complications of transcatheter aortic valve replacement: a review article
Cardiovascular-Kidney-Metabolic Syndrome Age Derived From Routine Health Checkup and Claims Data – Large-Scale Epidemiological Study
Background: The cardiovascular-kidney-metabolic (CKM) framework emphasizes the interplay of metabolic, renal, and cardiovascular abnormalities in cardiovascular disease risk. We aimed to develop a CKM syndrome age algorithm using routinely collected health checkup and claims data in Japan.Methods and results: We conducted a cohort study of 376,612 men and 478,853 women aged 20-79 years in the… Continue reading Cardiovascular-Kidney-Metabolic Syndrome Age Derived From Routine Health Checkup and Claims Data – Large-Scale Epidemiological Study
Phenotypic clustering and ABC pathway adherence in patients with atrial fibrillation at high risk of bleeding and stroke: Insights from three global registries
Background: Patients with atrial fibrillation (AF) who are at increased risk of both thrombotic and haemorrhagic events represent a heterogeneous and broad clinical entity, characterized by the presence of several Janus-faced risk factors. We aimed to identify clinical phenotypes and assess the association of ABC pathway adherence with one-year outcomes in patients with AF at… Continue reading Phenotypic clustering and ABC pathway adherence in patients with atrial fibrillation at high risk of bleeding and stroke: Insights from three global registries
Beyond conventional lipid markers: Atherogenic index of plasma and triglyceride-glucose index in relation to cardiometabolic multimorbidity in older adults
Purpose: This study aimed to compare the associations and predictive performance of atherogenic index of plasma (AIP) and the triglyceride-glucose (TyG) index for incident cardiometabolic multimorbidity (CMM).Methods: Data was analyzed from 2261 adults (mean age 63 years; 45.0% men) in the English Longitudinal Study of Ageing without a history of cardiometabolic disease at baseline (2008-2009).… Continue reading Beyond conventional lipid markers: Atherogenic index of plasma and triglyceride-glucose index in relation to cardiometabolic multimorbidity in older adults
Left Atrial Reservoir Strain Improves Sudden Cardiac Death Risk Stratification in Hypertrophic Cardiomyopathy
Background: Current risk scores for sudden cardiac death (SCD) in hypertrophic cardiomyopathy (HCM) have limited ability to identify high-risk subgroups. We aimed to investigate the prognostic value of left atrial reservoir strain (LARS) for SCD-related events and its utility for risk stratification.Methods: This retrospective cohort study included 1,761 patients with HCM from two referral centers.… Continue reading Left Atrial Reservoir Strain Improves Sudden Cardiac Death Risk Stratification in Hypertrophic Cardiomyopathy
Differential Prognostic Impact of Potent P2Y₁₂ Inhibitors in Patients With Acute Myocardial Infarction by Bleeding Risk
Background and objectives: Limited data on the comparative efficacy and safety of potent P2Y₁₂ inhibitors versus clopidogrel in patients with acute myocardial infarction (AMI) stratified by bleeding risk. This study evaluated the differential prognostic impact of potent P2Y₁₂ inhibitors in patients with AMI by bleeding risk.Methods: From the nationwide pooled registry of the Korea Acute… Continue reading Differential Prognostic Impact of Potent P2Y₁₂ Inhibitors in Patients With Acute Myocardial Infarction by Bleeding Risk
