Background/ObjectiveInsulin resistance is more prominent in men than women. If this involves adipose tissue is unknown and was presently examined.Subjects/MethodsAdipoIR (in vivo adipose insulin resistance index) was measured in 2344 women and 787 men. In 259 of the women and 54 of the men, insulin induced inhibition of lipolysis (acylglycerol breakdown) and stimulation of lipogenesis… Continue reading Sex differences in #adipose #insulin resistance are linked to #obesity, lipolysis and insulin receptor substrate 1
Author: aledopress
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The landscape of rare genetic variation associated with inflammatory #bowel disease and #Parkinson’s disease comorbidity
BackgroundInflammatory bowel disease (IBD) and Parkinson’s disease (PD) are chronic disorders that have been suggested to share common pathophysiological processes. LRRK2 has been implicated as playing a role in both diseases. Exploring the genetic basis of the IBD-PD comorbidity through studying high-impact rare genetic variants can facilitate the identification of the novel shared genetic factors underlying this… Continue reading The landscape of rare genetic variation associated with inflammatory #bowel disease and #Parkinson’s disease comorbidity
Wearing face #masks did not reduce risk of #COVID infection after first Omicron wave, research shows
After the first Omicron wave, research shows that many of the risks of Covid infection changed Before February 2022, always wearing face masks and being retired were associated with reduced risk, but not after Overseas travel was not associated with increased risk prior to February 2022, but then became a significant risk Peer reviewed – meta-regression- humans New… Continue reading Wearing face #masks did not reduce risk of #COVID infection after first Omicron wave, research shows
Association of ultra-processed #food consumption with all cause and cause specific #mortality: population based cohort study
Objective To examine the association of ultra-processed food consumption with all cause mortality and cause specific mortality.Design Population based cohort study.Setting Female registered nurses from 11 US states in the Nurses’ Health Study (1984-2018) and male health professionals from all 50 US states in the Health Professionals Follow-up Study (1986-2018).Participants 74 563 women and 39 501 men with no history of… Continue reading Association of ultra-processed #food consumption with all cause and cause specific #mortality: population based cohort study
Use of ancient #grains for the management of #diabetes mellitus: A systematic review and meta-analysis
Highlights•Oats, brown rice, and millet improve health outcomes in diabetes mellitus type 2.•The most prevalent grains tested in trials included oats, brown rice, and buckwheat.•The most outcomes studied in diabetes were related to cardiovascular risk factors.AimsA systematic review and meta-analysis of published randomized controlled trials was conducted to collate evidence from studies implementing ancient grains… Continue reading Use of ancient #grains for the management of #diabetes mellitus: A systematic review and meta-analysis
Consumption of #Olive Oil and Diet Quality and Risk of #Dementia-Related Death
Question Is the long-term consumption of olive oil associated with dementia-related death risk? Findings In a prospective cohort study of 92 383 adults observed over 28 years, the consumption of more than 7 g/d of olive oil was associated with a 28% lower risk of dementia-related death compared with never or rarely consuming olive oil, irrespective of diet… Continue reading Consumption of #Olive Oil and Diet Quality and Risk of #Dementia-Related Death
Neuronal activity in the anterior paraventricular nucleus of thalamus positively correlated with #sweetener consumption in mice
Although the brain can discriminate between various sweet substances, the underlying neural mechanisms of this complex behavior remain elusive. This study examines the role of the anterior paraventricular nucleus of the thalamus (aPVT) in governing sweet preference in mice. We fed the mice six different diets with equal sweetness for six weeks: control diet (CD),… Continue reading Neuronal activity in the anterior paraventricular nucleus of thalamus positively correlated with #sweetener consumption in mice
#ELECTRONIC NICOTINE PRODUCT USE IS ASSOCIATED WITH INCIDENT #HEART FAILURE – THE ALL OF US RESEARCH PROGRAM
An #osteoarthritis pathophysiological continuum revealed by molecular #biomarkers
We aimed to identify serum biomarkers that predict knee osteoarthritis (OA) before the appearance of radiographic abnormalities in a cohort of 200 women. As few as six serum peptides, corresponding to six proteins, reached AUC 77% probability to distinguish those who developed OA from age-matched individuals who did not develop OA up to 8 years… Continue reading An #osteoarthritis pathophysiological continuum revealed by molecular #biomarkers
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