Maternal gut microbiome–induced IgG regulates neonatal gut microbiome and immunity

Breast milk IgG adds valueAlthough the most abundant class of antibody present in breast milk is IgA, maternal IgG antibodies also get transferred into breast milk via the neonatal Fc receptor. Sanidad et al. used mouse models to investigate the capacity of breast milk IgG to protect against pathogens and promote the establishment of a …

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Evidence for a causal association between #milk intake and cardiometabolic disease outcomes using a two-sample Mendelian Randomization analysis in up to 1,904,220 individuals

High milk intake has been associated with cardio-metabolic risk. We conducted a Mendelian Randomization (MR) study to obtain evidence for the causal relationship between milk consumption and cardio-metabolic traits using the lactase persistence (LCT-13910 C > T, rs4988235) variant as an instrumental variable. MethodsWe tested the association of LCT genotype with milk consumption (for validation) and with …

Continue reading Evidence for a causal association between #milk intake and cardiometabolic disease outcomes using a two-sample Mendelian Randomization analysis in up to 1,904,220 individuals

Reservoirs of antimicrobial resistance genes in retail raw milk

Background It has been estimated that at least 3% of the USA population consumes unpasteurized (raw) milk from animal sources, and the demand to legalize raw milk sales continues to increase. However, consumption of raw milk can cause foodborne illness and be a source of bacteria containing transferrable antimicrobial resistance genes (ARGs). To obtain a …

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