Vegetarian Dietary Patterns and Cardiometabolic Risk in People With or at High Risk of Cardiovascular DiseaseA Systematic Review and Meta-analysis

MPORTANCE Plant-based diets are known to improve cardiometabolic risk in the general population, but their effects on people at high risk of cardiovascular diseases (CVDs) remain inconclusive.OBJECTIVE To assess the association of vegetarian diets with major cardiometabolic risk factors,including low-density lipoprotein cholesterol (LDL-C), hemoglobin A1c (HbA1c), systolic blood pressure (SBP), and body weight in people… Continue reading Vegetarian Dietary Patterns and Cardiometabolic Risk in People With or at High Risk of Cardiovascular DiseaseA Systematic Review and Meta-analysis

Accelerometer-Derived “Weekend Warrior” Physical Activity and Incident Cardiovascular Disease

Guidelines recommend 150 minutes or more of moderate to vigorous physical activity (MVPA) per week for overall health benefit, but the relative effects of concentrated vs more evenly distributed activity are unclear.Objective  To examine associations between an accelerometer-derived “weekend warrior” pattern (ie, most MVPA achieved over 1-2 days) vs MVPA spread more evenly with risk of… Continue reading Accelerometer-Derived “Weekend Warrior” Physical Activity and Incident Cardiovascular Disease

Opting for olive oil could boost brain healthRegular olive oil consumption associated with 28% lower risk of fatal dementia

oil as part of a Mediterranean dietary pattern has also been shown to help protect against cognitive decline. Tessier cautioned that the research is observational and does not prove that olive oil is the cause of the reduced risk of fatal dementia. Additional studies such as randomized controlled trials would be needed to confirm the effects… Continue reading Opting for olive oil could boost brain healthRegular olive oil consumption associated with 28% lower risk of fatal dementia

The influence of emotion regulation strategies and sleep quality on depression and anxiety

Chronic stress is a major risk factor for a number of mental health disorders, including depression and pathological anxiety. Adaptive cognitive emotion regulation (CER) strategies (i.e. positively-focused thought processes) can help to prevent psychiatric disturbance when enduring unpleasant and stressful experiences, but little is known about the inter-individual factors that govern their success. Sleep plays an important… Continue reading The influence of emotion regulation strategies and sleep quality on depression and anxiety

Hearing intervention versus health education control to reduce cognitive decline in older adults with hearing loss in the USA (ACHIEVE): a multicentre, randomised controlled trial

Hearing loss is associated with increased cognitive decline and incident dementia in older adults. We aimed to investigate whether a hearing intervention could reduce cognitive decline in cognitively healthy older adults with hearing loss.MethodsThe ACHIEVE study is a multicentre, parallel-group, unmasked, randomised controlled trial of adults aged 70–84 years with untreated hearing loss and without… Continue reading Hearing intervention versus health education control to reduce cognitive decline in older adults with hearing loss in the USA (ACHIEVE): a multicentre, randomised controlled trial

Vitamin D status & associations with inflammation in older adults

Research studies have observed associations of vitamin D with inflammation but data in representative older adult studies is lacking. We aimed to investigate the association of C-reactive protein (CRP) with vitamin D status in a representative sample of the older Irish population. The concentrations of 25-hydroxyvitamin D (25(OH)D) and CRP was measured in 5,381 community… Continue reading Vitamin D status & associations with inflammation in older adults

Physical Activity Dose and Depression in a Cohort of Older Adults in The Irish Longitudinal Study on Ageing

Importance  Among older adults (aged ≥50 years), depression is associated with an increased risk of physical, social, and cognitive dysfunction. Regular moderate to vigorous physical activity (MVPA) has been associated with lower odds of depression. However, the lowest dose for protection against depression and the extent to which exceeding this level conveys additional protection are unknown.Objective  To… Continue reading Physical Activity Dose and Depression in a Cohort of Older Adults in The Irish Longitudinal Study on Ageing

Objectively Measured Visual Impairment and Dementia Prevalence in Older Adults in the US

Importance  Estimates of the association between visual impairment (VI) and dementia in the US population are based on self-reported survey data or measures of visual function that are at least 15 years old. Older adults are at high risk of VI and dementia so there is a need for up-to-date national estimates based on objective assessments.Objective  To… Continue reading Objectively Measured Visual Impairment and Dementia Prevalence in Older Adults in the US

Cognitive Activity and Onset Age of Incident Alzheimer Disease Dementia

Objective To test the hypothesis that higher level of cognitive activity predicts older age at dementia onset in Alzheimer disease (AD) dementia.Methods As part of a longitudinal cohort study, 1,903 older persons without dementia at enrollment reported their frequency of participation in cognitively stimulating activities. They had annual clinical evaluations to diagnose dementia and AD, and the… Continue reading Cognitive Activity and Onset Age of Incident Alzheimer Disease Dementia