Psychosocial stressors at work, like job strain and effort-reward imbalance (ERI), can increase coronary heart disease (CHD) risk. ERI indicates an imbalance between the effort and received rewards. Evidence about the adverse effect of combined exposure to these work stressors on CHD risk is scarce. This study examines the separate and combined effect of job… Continue reading Psychosocial #Stressors at #Work and #Coronary Heart Disease Risk in Men and Women: 18-Year Prospective Cohort Study of Combined Exposures
Dietary #Carbohydrate and #Fat Intakes and Risk of Mortality in the Japanese Population: the Japan Multi-Institutional Collaborative Cohort Study
BackgroundPrevious cohort studies have yielded contradictory findings regarding the associations of dietary carbohydrate and fat intakes with risks of mortality.ObjectivesWe examined long-term associations of carbohydrate and fat intakes with mortality.MethodsIn this cohort study, 34,893 men and 46,440 women aged 35–69 y (mean body mass index of 23.7 and 22.2 kg/m2, respectively) were followed up from the baseline survey (2004–2014)… Continue reading Dietary #Carbohydrate and #Fat Intakes and Risk of Mortality in the Japanese Population: the Japan Multi-Institutional Collaborative Cohort Study
#Nicotinamide enhances natural #killer cell function and yields remissions in patients with non-Hodgkin #lymphoma
Administration of haploidentical donor natural killer (NK) cells, rituximab, and IL-2 to patients with non-Hodgkin lymphoma (NHL) has been shown to be safe, but the objective response rate was low, suggesting that further strategies to improve NK cell engraftment and function are needed. Here, Cichocki and colleagues showed that supplementation with nicotinamide during ex vivo… Continue reading #Nicotinamide enhances natural #killer cell function and yields remissions in patients with non-Hodgkin #lymphoma
Seated And Supine Blood #Pressure And Risk Of #Cardiovascular Disease And Mortality From The Atherosclerosis Risk In Communities Study
Background Hypertension (HTN) while asleep is strongly associated with cardiovascular disease (CVD) and death. Whether HTN while supine in clinic is a risk factor for CVD independent of seated BP remains unknown.Objectives To determine the relationship between supine HTN and adverse CVD.Methods The Atherosclerosis Risk in Communities (ARIC) Study measured supine and seated BP during visit 1 (1987-1989).… Continue reading Seated And Supine Blood #Pressure And Risk Of #Cardiovascular Disease And Mortality From The Atherosclerosis Risk In Communities Study
#Covid symptoms follow a very distinctive #pattern now – as common signs change, doctors discover
IN a short space of just a few years, the symptoms of Covid have changed in some surprising ways. Doctors are finding signs of the diseases are now following a very distinctive pattern. How Covid symptoms are changing thanks to heard immunity from prior infections and vaccines The illness’ past telltale signs, like the loss… Continue reading #Covid symptoms follow a very distinctive #pattern now – as common signs change, doctors discover
#Dementia Risk of Direct Oral Anticoagulants Versus Warfarin for Atrial #Fibrillation: Systematic Review and Meta-Analysis
BackgroundDirect-acting oral anticoagulants (DOACs) have demonstrated superior efficacy in preventing stroke and death compared with warfarin in patients with atrial fibrillation (AF), but their influence on dementia risk remains unclear.ObjectivesThe purpose of this study was to evaluate the relative risks of dementia in DOAC vs warfarin in patients with AF.MethodsAn electronic literature search was conducted… Continue reading #Dementia Risk of Direct Oral Anticoagulants Versus Warfarin for Atrial #Fibrillation: Systematic Review and Meta-Analysis
Stress test abnormalities reveal more than just cardiovascular risks, Mayo Clinic study finds
The treadmill exercise test with electrocardiogram (ECG), also known as an exercise stress test, is one of the most familiar tests in medicine. While exercise testing typically is focused on diagnosing coronary artery disease, a recent study from Mayo Clinic finds that exercise test abnormalities, such as low functional aerobic capacity, predicted non-cardiovascular causes of death such as… Continue reading Stress test abnormalities reveal more than just cardiovascular risks, Mayo Clinic study finds
Assessment of Gastroesophageal #Reflux Symptoms and #Sleep Quality Among Women in the Nurses’ Health Study II
Limited data exist on the association of gastroesophageal reflux (GER) symptoms with sleep quality.Objective To prospectively investigate the association between GER symptoms and sleep quality.Design, Setting, and Participants This prospective cohort study included data from the Nurses’ Health Study II of female nurses in the US. Participants self-reported the frequency and duration of GER symptoms beginning June… Continue reading Assessment of Gastroesophageal #Reflux Symptoms and #Sleep Quality Among Women in the Nurses’ Health Study II
On this day … 16 September 1893
The Preston Chronicle carried a report from an angry meeting at Freckleton at which residents protested about ‘the abominable nuisance caused by the Preston Corporation and other public bodies bringing their sewage into the village’. The main target for the protests was Freckleton Farm. The sewage of both Preston and Fulwood was carried eight miles… Continue reading On this day … 16 September 1893
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