Background: Foods with protein claims (PCs) targeted at the general population are increasingly sought after by consumers because they think they are healthy. However, they may contain other nutrients that pose a health risk. Objectives: Therefore, the aim of this work was to carry out a comprehensive evaluation of foods with PC and compare them… Continue reading Are Foods with #Protein Claims Healthy? A Study of the Spanish Market
Stereotactic Body Radiotherapy vs #Sorafenib Alone in #Hepatocellular Carcinoma
Question Does stereotactic body radiation therapy (SBRT) prior to systemic therapy improve overall survival compared with systemic therapy alone in patients with locally advanced hepatocellular carcinoma (HCC)?Findings This phase 3 randomized clinical trial found that the use of SBRT prior to sorafenib was associated with clinically important but not statistically significant improved overall survival in… Continue reading Stereotactic Body Radiotherapy vs #Sorafenib Alone in #Hepatocellular Carcinoma
The tradeoff of #solitude? #Restoration and relatedness across shades of solitude
Social interaction and solitude entail tradeoffs. Communicate Bond Belong (CBB) theory holds that social interaction can foster relatedness with others at the cost of social energy, whereas solitude can restore social energy at the cost of relatedness. The current study empirically tests this tradeoff of solitude and its implications for well-being by investigating different degrees… Continue reading The tradeoff of #solitude? #Restoration and relatedness across shades of solitude
Blood #Pressure Variability and #Cognition in Black and White Older Adults Over 18 Years of Follow-up
Background and ObjectivesHypertension is a well-established cardiovascular risk factor for cognitive function. As blood pressure fluctuates because of aging-related changes, we examined the association between visit-to-visit blood pressure variability (BPV) and cognition in older adults. MethodsThis prospective observational cohort study included 4,770 individuals aged older than 65 years with repeated blood pressure assessment participating in… Continue reading Blood #Pressure Variability and #Cognition in Black and White Older Adults Over 18 Years of Follow-up
Urinary #tartaric acid as a biomarker of #wine consumption and #cardiovascular risk: the PREDIMED trial
Background and AimsModerate wine consumption has been associated with lower cardiovascular disease (CVD) risk in older populations. However, wine consumption information through self-reports is prone to measurement errors inherent to subjective assessments. The aim of this study was to evaluate the association between urinary tartaric acid, an objective biomarker of wine consumption, and the rate… Continue reading Urinary #tartaric acid as a biomarker of #wine consumption and #cardiovascular risk: the PREDIMED trial
Long-Term #Aspirin vs #Clopidogrel After #Coronary Stenting by Bleeding Risk and Procedural Complexity
Question What is the comparative effectiveness of clopidogrel vs aspirin monotherapy in the chronic maintenance period after percutaneous coronary intervention (PCI) according to bleeding risk and procedural complexity?Findings In this post hoc analysis of the HOST-EXAM Extended clinical trial, clopidogrel monotherapy was associated with a reduction in thrombotic and bleeding risks compared with aspirin, regardless… Continue reading Long-Term #Aspirin vs #Clopidogrel After #Coronary Stenting by Bleeding Risk and Procedural Complexity
Impact of #coffee intake on human #aging: Epidemiology and cellular mechanisms
Highlights•The regular consumption of moderate doses of coffee attenuates all-cause mortality•Coffee intake attenuates age-associated diseases (cardiovascular, stroke, cancer)•Coffee and its main components (caffeine, chlorogenic acids) control stress adaptation•Coffee intake preserves the main biological mechanisms of aging AbstractThe conception of coffee consumption has undergone a profound modification, evolving from a noxious habit into a safe lifestyle… Continue reading Impact of #coffee intake on human #aging: Epidemiology and cellular mechanisms
Associations of accelerometer-measured #physical activity, #sedentary behaviour, and #sleep with next-day #cognitive performance in older adults: a micro-longitudinal study
BackgroundPrevious studies suggest short-term cognitive benefits of physical activity occurring minutes to hours after exercise. Whether these benefits persist the following day and the role of sleep is unclear. We examined associations of accelerometer-assessed physical activity, sedentary behaviour, and sleep with next-day cognitive performance in older adults.MethodsBritish adults aged 50-83 years (N = 76) without evidence of… Continue reading Associations of accelerometer-measured #physical activity, #sedentary behaviour, and #sleep with next-day #cognitive performance in older adults: a micro-longitudinal study
Screening for advanced #liver fibrosis due to metabolic dysfunction-associated #steatotic liver disease alongside #retina scanning in people with type 2 diabetes: a cross-sectional study
BackgroundInternational guidelines suggest screening for advanced fibrosis due to metabolic dysfunction-associated steatotic liver disease in people with type 2 diabetes, but how to implement these guidelines in clinical care remains unclear. We hypothesise that examination with VCTE could be implemented simultaneously with retina scanning with a high acceptance rate in people with type 2 diabetes.… Continue reading Screening for advanced #liver fibrosis due to metabolic dysfunction-associated #steatotic liver disease alongside #retina scanning in people with type 2 diabetes: a cross-sectional study
