Cardiovascular diseases remain a leading global cause of mortality, underscoring the urgent need for intelligent diagnostic tools to enhance early detection, prediction, diagnosis, prevention, treatment, and recovery. This demand has spurred the advancement of wearable and flexible technologies, revolutionizing continuous, noninvasive, and remote heart sound (HS) monitoring—a vital avenue for assessing heart activity. The conventional… Continue reading Advancements in wearable #heart sounds devices for the monitoring of #cardiovascular diseases
Late #eating is associated with poor #glucose tolerance, independent of body weight, fat mass, energy intake and diet composition in prediabetes or early onset type 2 #diabetes
This study investigates the impact of habitual late calorie intake on glucose metabolism in adults with overweight or obesity and diet or metformin-controlled prediabetes or type 2 diabetes independently of body weight, fat mass, energy intake or diet composition. Participants (n = 26) were classified as Later Eaters (LE) if ≥45% daily calories were consumed after 5 pm… Continue reading Late #eating is associated with poor #glucose tolerance, independent of body weight, fat mass, energy intake and diet composition in prediabetes or early onset type 2 #diabetes
#Breakfast energy intake and dietary quality and trajectories of #cardiometabolic risk factors in older adults
Highlights•Eating 20−30% of daily energy in breakfast links to less adiposity in older adults.•It is also related to less triglycerides and more HDL cholesterol (HDL-C).•A high-quality breakfast is linked to better adiposity, HDL-C, and kidney function.•Healthy breakfast habits relate to healthy aging by improving heart risk factors. ObjectivesNot skipping breakfast is associated with a better… Continue reading #Breakfast energy intake and dietary quality and trajectories of #cardiometabolic risk factors in older adults
Short #Sleep Duration and #Hypertension: A Double Hit for the #Brain
Short sleep duration has been associated with an increased risk of cognitive impairment and dementia. Short sleep is associated with elevated blood pressure, yet the combined insult of short sleep and hypertension on brain health remains unclear. We assessed whether the association of sleep duration with cognition and vascular brain injury was moderated by hypertensive… Continue reading Short #Sleep Duration and #Hypertension: A Double Hit for the #Brain
#Teabag-derived micro/#nanoplastics (true-to-life MNPLs) as a surrogate for real-life exposure scenarios
Highlights•Nanoplastics were obtained from three teabag brands during a standard preparation.•ATR-FTIR shows nylon, polypropylene, and cellulose as constituents.•MNPLs release was higher for propylene and lower for nylon.•Uptake in Caco-2, HT29, and HT29-MTX human intestinal cells was determined.•Cell uptake depends on both cell type and chemical constitution of released MNPLs. AbstractThe potential health implications of environmental… Continue reading #Teabag-derived micro/#nanoplastics (true-to-life MNPLs) as a surrogate for real-life exposure scenarios
#Propranolol Reduces #Parkinson’s #Tremor and Inhibits Tremor-Related Activity in the Motor Cortex: A Placebo-Controlled Crossover Trial
AbstractObjectiveParkinson's disease (PD) resting tremor is thought to be initiated in the basal ganglia and amplified in the cerebello-thalamo-cortical circuit. Because stress worsens tremor, the noradrenergic system may play a role in amplifying tremor. We tested if and how propranolol, a non-selective beta-adrenergic receptor antagonist, reduces PD tremor and whether or not this effect is… Continue reading #Propranolol Reduces #Parkinson’s #Tremor and Inhibits Tremor-Related Activity in the Motor Cortex: A Placebo-Controlled Crossover Trial
Better #diet quality is associated with reduced body #pain in adults regardless of adiposity: Findings from the Whyalla Intergenerational Study of Health
Highlights•Better diet quality had a direct (beneficial) effect on pain.•Higher consumption of core foods was related to less pain in women, but not men.•Adiposity did not mediate the relationship between diet quality and pain.•Strategies for pain management should consider diet quality. AbstractDietary intake has been associated with pain and physical function, but it is unclear… Continue reading Better #diet quality is associated with reduced body #pain in adults regardless of adiposity: Findings from the Whyalla Intergenerational Study of Health
The Role of Dietary #Magnesium in #Cardiovascular Disease
In the past 20 years, a large number of epidemiological studies, randomized controlled trials, and meta-analyses have found an inverse relationship between magnesium intake or serum magnesium and cardiovascular disease, indicating that low magnesium status is associated with hypertension, coronary artery calcification, stroke, ischemic heart disease, atrial fibrillation, heart failure, and cardiac mortality. Controlled metabolic… Continue reading The Role of Dietary #Magnesium in #Cardiovascular Disease
Restrictive versus Liberal #Transfusion in Myocardial #Infarction — A Patient-Level Meta-Analysis
BackgroundClinical guidelines have concluded that there are insufficient data to provide recommendations for the hemoglobin threshold for the use of red cell transfusion in patients with acute myocardial infarction (MI) and anemia. After the recent publication of the Myocardial Infarction and Transfusion (MINT) trial, we performed an individual patient-level data meta-analysis to evaluate the effect… Continue reading Restrictive versus Liberal #Transfusion in Myocardial #Infarction — A Patient-Level Meta-Analysis
