Short sleep duration has been associated with an increased risk of cognitive impairment and dementia. Short sleep is associated with elevated blood pressure, yet the combined insult of short sleep and hypertension on brain health remains unclear. We assessed whether the association of sleep duration with cognition and vascular brain injury was moderated by hypertensive… Continue reading Short #Sleep Duration and #Hypertension: A Double Hit for the #Brain
#Teabag-derived micro/#nanoplastics (true-to-life MNPLs) as a surrogate for real-life exposure scenarios
Highlights•Nanoplastics were obtained from three teabag brands during a standard preparation.•ATR-FTIR shows nylon, polypropylene, and cellulose as constituents.•MNPLs release was higher for propylene and lower for nylon.•Uptake in Caco-2, HT29, and HT29-MTX human intestinal cells was determined.•Cell uptake depends on both cell type and chemical constitution of released MNPLs. AbstractThe potential health implications of environmental… Continue reading #Teabag-derived micro/#nanoplastics (true-to-life MNPLs) as a surrogate for real-life exposure scenarios
#Propranolol Reduces #Parkinson’s #Tremor and Inhibits Tremor-Related Activity in the Motor Cortex: A Placebo-Controlled Crossover Trial
AbstractObjectiveParkinson's disease (PD) resting tremor is thought to be initiated in the basal ganglia and amplified in the cerebello-thalamo-cortical circuit. Because stress worsens tremor, the noradrenergic system may play a role in amplifying tremor. We tested if and how propranolol, a non-selective beta-adrenergic receptor antagonist, reduces PD tremor and whether or not this effect is… Continue reading #Propranolol Reduces #Parkinson’s #Tremor and Inhibits Tremor-Related Activity in the Motor Cortex: A Placebo-Controlled Crossover Trial
Better #diet quality is associated with reduced body #pain in adults regardless of adiposity: Findings from the Whyalla Intergenerational Study of Health
Highlights•Better diet quality had a direct (beneficial) effect on pain.•Higher consumption of core foods was related to less pain in women, but not men.•Adiposity did not mediate the relationship between diet quality and pain.•Strategies for pain management should consider diet quality. AbstractDietary intake has been associated with pain and physical function, but it is unclear… Continue reading Better #diet quality is associated with reduced body #pain in adults regardless of adiposity: Findings from the Whyalla Intergenerational Study of Health
The Role of Dietary #Magnesium in #Cardiovascular Disease
In the past 20 years, a large number of epidemiological studies, randomized controlled trials, and meta-analyses have found an inverse relationship between magnesium intake or serum magnesium and cardiovascular disease, indicating that low magnesium status is associated with hypertension, coronary artery calcification, stroke, ischemic heart disease, atrial fibrillation, heart failure, and cardiac mortality. Controlled metabolic… Continue reading The Role of Dietary #Magnesium in #Cardiovascular Disease
Restrictive versus Liberal #Transfusion in Myocardial #Infarction — A Patient-Level Meta-Analysis
BackgroundClinical guidelines have concluded that there are insufficient data to provide recommendations for the hemoglobin threshold for the use of red cell transfusion in patients with acute myocardial infarction (MI) and anemia. After the recent publication of the Myocardial Infarction and Transfusion (MINT) trial, we performed an individual patient-level data meta-analysis to evaluate the effect… Continue reading Restrictive versus Liberal #Transfusion in Myocardial #Infarction — A Patient-Level Meta-Analysis
Are Foods with #Protein Claims Healthy? A Study of the Spanish Market
Background: Foods with protein claims (PCs) targeted at the general population are increasingly sought after by consumers because they think they are healthy. However, they may contain other nutrients that pose a health risk. Objectives: Therefore, the aim of this work was to carry out a comprehensive evaluation of foods with PC and compare them… Continue reading Are Foods with #Protein Claims Healthy? A Study of the Spanish Market
Stereotactic Body Radiotherapy vs #Sorafenib Alone in #Hepatocellular Carcinoma
Question Does stereotactic body radiation therapy (SBRT) prior to systemic therapy improve overall survival compared with systemic therapy alone in patients with locally advanced hepatocellular carcinoma (HCC)?Findings This phase 3 randomized clinical trial found that the use of SBRT prior to sorafenib was associated with clinically important but not statistically significant improved overall survival in… Continue reading Stereotactic Body Radiotherapy vs #Sorafenib Alone in #Hepatocellular Carcinoma
The tradeoff of #solitude? #Restoration and relatedness across shades of solitude
Social interaction and solitude entail tradeoffs. Communicate Bond Belong (CBB) theory holds that social interaction can foster relatedness with others at the cost of social energy, whereas solitude can restore social energy at the cost of relatedness. The current study empirically tests this tradeoff of solitude and its implications for well-being by investigating different degrees… Continue reading The tradeoff of #solitude? #Restoration and relatedness across shades of solitude
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