It is uncertain whether beta-blockers (BBs) are beneficial in contemporary stable patients with prior myocardial infarction (MI). Therefore, we sought to examine the effectiveness of BB use in this population.. ..We included 33,811 patients with prior MI, of whom 21,440 (63.4%) were dispensed a BB. The median age was 78 years, and 56% were male.… Continue reading Clinical Outcomes With #Beta-Blocker Use in Patients With Recent History of Myocardial #Infarction
#Potato Protein Isolate Stimulates #Muscle Protein Synthesis at Rest and with Resistance Exercise in Young Women
Skeletal muscle myofibrillar protein synthesis (MPS) increases in response to protein feeding and to resistance exercise (RE), where each stimuli acts synergistically when combined. The efficacy of plant proteins such as potato protein (PP) isolate to stimulate MPS is unknown. We aimed to determine the effects of PP ingestion on daily MPS with and without… Continue reading #Potato Protein Isolate Stimulates #Muscle Protein Synthesis at Rest and with Resistance Exercise in Young Women
Mid-Term Effects of Pulmonary #Rehabilitation on Cognitive Function in People with Severe Chronic Obstructive #Pulmonary Disease
Cognitive dysfunction is a common impairment associated with COPD. However, little is known about 1) its prevalence among those subjects referred for pulmonary rehabilitation (PR), 2) how it may affect the benefit of PR, 3) whether PR improves cognitive function and 4) whether cognitive dysfunction affects the usability of telehealth technology usually used to deliver… Continue reading Mid-Term Effects of Pulmonary #Rehabilitation on Cognitive Function in People with Severe Chronic Obstructive #Pulmonary Disease
Long-term dietary #flavonoid intake and risk of #Alzheimer disease and related dementias in the Framingham Offspring Cohort
Findings from existing prospective observational studies on the protective associations of flavonoid intake and the risk of Alzheimer disease and related dementias (ADRD) are inconsistent largely due to limitations of these studies.. ..Over an average follow-up of 19.7 y in 2801 participants (mean baseline age = 59.1 y; 52% females), there were 193 ADRD events… Continue reading Long-term dietary #flavonoid intake and risk of #Alzheimer disease and related dementias in the Framingham Offspring Cohort
Rebaudioside affords hepatoprotection ameliorating sugar sweetened beverage- induced nonalcoholic #steatohepatitis
Sugar-sweetened beverage consumption is a known independent risk factor for nonalcoholic steatohepatitis (NASH). Non-caloric sweeteners (NCS) are food additives providing sweetness without calories and are considered safe and/or not metabolized by the liver. The potential role of newer NCS in the regulation of NASH, however, remain unknown. Our study aimed to determine the impact of… Continue reading Rebaudioside affords hepatoprotection ameliorating sugar sweetened beverage- induced nonalcoholic #steatohepatitis
Association of Blood Pressure Lowering With Incident #Dementia or Cognitive Impairment A Systematic Review and Meta-analysis
..The mean (SD) age of trial participants was 69 (5.4) years and 40 617 (42.2%) were women. The mean systolic baseline blood pressure was 154 (14.9) mm Hg and the mean diastolic blood pressure was 83.3 (9.9) mm Hg. The mean duration of follow-up was 49.2 months. Blood pressure lowering with antihypertensive agents compared with… Continue reading Association of Blood Pressure Lowering With Incident #Dementia or Cognitive Impairment A Systematic Review and Meta-analysis
Fine Particulate Matter Air #Pollution and Mortality among Pediatric, Adolescent, and Young Adult Cancer Patients
Air pollution is a carcinogen and causes pulmonary and cardiac complications. We examined the association of fine particulate matter pollution (PM2.5) and mortality from cancer and all causes among pediatric, adolescent, and young adult (AYA) patients with cancer in Utah, a state with considerable variation in PM2.5.. ..Increases in PM2.5 per 5 μg/m3 were associated… Continue reading Fine Particulate Matter Air #Pollution and Mortality among Pediatric, Adolescent, and Young Adult Cancer Patients
ACUTE #KIDNEY INJURY IN PATIENTS HOSPITALIZED WITH #COVID-19
The rate of acute kidney injury (AKI) associated with patients hospitalized with Covid-19, and associated outcomes are not well understood. This study describes the presentation, risk factors and outcomes of AKI in patients hospitalized with Covid-19. We reviewed the health records for all patients hospitalized with Covid-19 between March 1, and April 5, 2020, at… Continue reading ACUTE #KIDNEY INJURY IN PATIENTS HOSPITALIZED WITH #COVID-19
Comparison between clinical and ultrasound assessment of the ankle region in juvenile idiopathic #arthritis
To compare frequency of joint and tendon disease on ultrasound (US) and clinical examination (CE), and to investigate agreement between US and CE in ankles with clinically active juvenile idiopathic arthritis (JIA).. ..A total of 163 joints in 89 ankles had active synovitis on US. The tibiotalar joint (TTJ) was the most commonly affected joint… Continue reading Comparison between clinical and ultrasound assessment of the ankle region in juvenile idiopathic #arthritis