The Cognitive Debt hypothesis proposes that repetitive negative thinking (RNT), a modifiable process common to many psychological risk factors for Alzheimer's disease (AD) may itself increase risk. We sought to empirically examine relationships between RNT and markers of AD, compared with anxiety and depression symptoms. ..RNT was associated with decline in global cognition (P =… Continue reading Repetitive negative #thinking is associated with #amyloid, tau, and cognitive decline
ACE2 Expression is Increased in the Lungs of Patients with Comorbidities Associated with Severe COVID-19
Patients who died from COVID-19 often had comorbidities, such as hypertension, diabetes, and chronic obstructive lung disease. Although angiotensin-converting enzyme 2 (ACE2) is crucial for SARS-CoV2 to bind and enter host cells, no study has systematically assessed the ACE2 expression in the lungs of patients with these diseases. Here, we analyzed over 700 lung transcriptome… Continue reading ACE2 Expression is Increased in the Lungs of Patients with Comorbidities Associated with Severe COVID-19
Current and 1-Year Psychological and Physical Effects of Replacing Sedentary Time With Time in Other Behaviors
Sedentary time is inversely associated with health. Capturing 24 hours of behavior (i.e., sleep, sedentary, light physical activity, and moderate-to-vigorous physical activity) is necessary to understand behavior–health associations.. ..Cross-sectional analyses revealed substituting prolonged sedentary time for sleep was associated with lower stress (standardized β= −0.11), better mood (−0.12), and lower BMI (−0.10). Substituting total or… Continue reading Current and 1-Year Psychological and Physical Effects of Replacing Sedentary Time With Time in Other Behaviors
Daily listening to Mozart reduces seizures in individuals with epilepsy: A randomized control study
Epilepsy is one of the most common neurological disorders . Many individuals continue to have seizures despite medical and surgical treatments, suggesting adjunctive management strategies are required. Promising effects of daily listening to Mozart on reducing seizure frequency in individuals with epilepsy have been demonstrated over the last 20 years, but not in a rigorously… Continue reading Daily listening to Mozart reduces seizures in individuals with epilepsy: A randomized control study
Atrial Cardiopathy in the Absence of Atrial Fibrillation Increases Risk of Ischemic Stroke, Incident Atrial Fibrillation, and Mortality and Improves Stroke Risk Prediction
Atrial fibrillation (AF) is a major, often undetected, cardiac cause of stroke. Markers of atrial cardiopathy, including left atrial enlargement (LAE) or excessive atrial ectopy (EAE) increase the risk of AF and have shown associations with stroke. We sought to determine whether these markers improve stroke risk prediction beyond traditional vascular risk factors (eg CHA2DS2‐VASc… Continue reading Atrial Cardiopathy in the Absence of Atrial Fibrillation Increases Risk of Ischemic Stroke, Incident Atrial Fibrillation, and Mortality and Improves Stroke Risk Prediction
Cigarette Smoking and Incident Stroke in Blacks of the Jackson Heart Study
Blacks are disproportionately affected by stroke compared with whites; however, less is known about the relationship between stroke and cigarette smoking in blacks. Therefore, we evaluated the relationship between cigarette smoking and all incident stroke in the JHS (Jackson Heart Study).. JHS participants without a history of stroke (n=4410) were classified by self‐reported baseline smoking… Continue reading Cigarette Smoking and Incident Stroke in Blacks of the Jackson Heart Study
Screening for Anxiety in Adolescent and Adult Women: A Recommendation From the Women’s Preventive Services Initiative
..Recommendation: The WPSI recommends screening for anxiety in women and adolescent girls aged 13 years or older who are not currently diagnosed with anxiety disorders, including pregnant and postpartum women. Optimal screening intervals are unknown, and clinical judgment should be used to determine frequency. When screening suggests the presence of anxiety, further evaluation is necessary… Continue reading Screening for Anxiety in Adolescent and Adult Women: A Recommendation From the Women’s Preventive Services Initiative
Association of Obstructive Sleep Apnea with Nighttime Blood Pressure in African Americans: the Jackson Heart Study
Obstructive sleep apnea (OSA), nocturnal hypertension, and non-dipping systolic blood pressure (BP) are each highly prevalent among African Americans. However, few data are available on the association between OSA and nighttime BP in this population.. ..Among 206 participants who completed ABPM and participated in the Jackson Heart Sleep Study, 50.5% had nocturnal hypertension and 26.2%… Continue reading Association of Obstructive Sleep Apnea with Nighttime Blood Pressure in African Americans: the Jackson Heart Study
The Impact of Optimized Daylight and Views on the Sleep Duration and Cognitive Performance of Office Workers
A growing awareness has recently emerged on the health benefits of exposure to daylight and views. Daylight exposure is linked to circadian rhythm regulation, which can have significant impacts on sleep quality and cognitive function. Views of nature have also been shown to impact emotional affect and performance. This study explores the impact of optimized… Continue reading The Impact of Optimized Daylight and Views on the Sleep Duration and Cognitive Performance of Office Workers
2 Medical News 