Rapid eye movement (#REM) sleep has been linked with health outcomes, but little is known about the relationship between REM sleep and mortality.. ..The MrOS cohort included 2675 individuals (2675 men [100%]; mean [SD] age, 76.3 [5.5] years) and was followed up for a median (interquartile range) of 12.1 (7.8-13.2) years. The WSC cohort included 1386… Continue reading Association of Rapid Eye Movement #Sleep With Mortality in Middle-aged and Older Adults
Effect of Vitamin #D Supplementation on the Incidence of #Diabetes Mellitus
The effect of vitamin D supplementation on the risk of type 2 diabetes mellitus (T2DM) remains controversial because most randomized controlled trials (RCTs) have been small or have reported low doses of vitamin D.. ..Nine RCTs were included (43 559 participants). The mean age (standard deviation) was 63.5 (6.7) years. The RR for vitamin D… Continue reading Effect of Vitamin #D Supplementation on the Incidence of #Diabetes Mellitus
Women Have a Lower Risk of Nonalcoholic Fatty Liver Disease but a Higher Risk of Progression Vs Men: A Systematic Review and Meta-analysis
The risk of nonalcoholic fatty liver disease (NAFLD) and its progression may differ between men and women. We conducted a systematic review and meta-analysis to determine the relationship between sex and NAFLD, nonalcoholic steatohepatitis (NASH), and advanced NAFLD fibrosis.. ..Our final analysis comprised 54 studies. Samples sizes were 62,239 for the NAFLD analysis, 5428 for… Continue reading Women Have a Lower Risk of Nonalcoholic Fatty Liver Disease but a Higher Risk of Progression Vs Men: A Systematic Review and Meta-analysis
Apathy, but not depression, predicts all-cause dementia in cerebral small vessel disease
To determine whether apathy or depression predicts all-cause dementia in small vessel disease (SVD) patients. Methods Analyses used two prospective cohort studies of SVD: St. George’s Cognition and Neuroimaging in Stroke (SCANS; n=121) and Radboud University Nijmegen Diffusion Tensor and Magnetic Resonance Cohort (RUN DMC; n=352). Multivariate Cox regressions were used to predict dementia using… Continue reading Apathy, but not depression, predicts all-cause dementia in cerebral small vessel disease
JOINT GUIDANCE ON VITAMIN D IN THE ERA OF COVID-19 FROM THE ASBMR, AACE, ENDOCRINE SOCIETY, ECTS, NOF, AND IOF
In response to the current COVID-19 global pandemic, and the attendant impact on outdoor physical activity and leisure time, the American Society for Bone and Mineral Research (ASBMR), American Association of Clinical Endocrinologists (AACE), Endocrine Society, European Calcified Tissue Society (ECTS), National Osteoporosis Foundation (NOF), and International Osteoporosis Foundation (IOF) remind individuals of the importance… Continue reading JOINT GUIDANCE ON VITAMIN D IN THE ERA OF COVID-19 FROM THE ASBMR, AACE, ENDOCRINE SOCIETY, ECTS, NOF, AND IOF
Intake of whole grain foods and risk of type 2 diabetes: results from three prospective cohort studies
..During 4 618 796 person years of follow-up, 18 629 participants with type 2 diabetes were identified. Total whole grain consumption was categorized into five equal groups of servings a day for the three cohorts. After adjusting for lifestyle and dietary risk factors for diabetes, participants in the highest category for total whole grain consumption had a 29%… Continue reading Intake of whole grain foods and risk of type 2 diabetes: results from three prospective cohort studies
2020 Conversion of Urine Protein–Creatinine Ratio or Urine Dipstick Protein to Urine Albumin–Creatinine Ratio for Use in Chronic Kidney Disease Screening and Prognosis
Measuring albuminuria is the preferred method for defining and staging chronic kidney disease (CKD), but total urine protein or dipstick protein is often measured instead. This analysis presents equations for converting urine protein–creatinine ratio and dipstick protein to urine albumin–creatinine ratio, and finds that both may help in CKD screening, staging, and prognosis.. Equations to… Continue reading 2020 Conversion of Urine Protein–Creatinine Ratio or Urine Dipstick Protein to Urine Albumin–Creatinine Ratio for Use in Chronic Kidney Disease Screening and Prognosis
Food & mood: a review of supplementary prebiotic and probiotic interventions in the treatment of anxiety and depression in adult
A bidirectional relationship exists between the brain and the gastrointestinal tract. Foods containing bacteria that positively influence the gastrointestinal microbiome are termed, probiotics; compounds that promote the flourishing of these bacteria are termed, prebiotics. Whether microbiome influencing therapies could treat psychiatric conditions, including depression and anxiety, is an area of interest. Presently, no established consensus… Continue reading Food & mood: a review of supplementary prebiotic and probiotic interventions in the treatment of anxiety and depression in adult
Generative Feedback Explains Distinct Brain Activity Codes for Seen and Mental Images
The relationship between mental imagery and vision is a long-standing problem in neuroscience. Currently, it is not known whether differences between the activity evoked during vision and reinstated during imagery reflect different codes for seen and mental images. To address this problem, we modeled mental imagery in the human brain as feedback in a hierarchical… Continue reading Generative Feedback Explains Distinct Brain Activity Codes for Seen and Mental Images
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