The incidence of inflammatory bowel diseases has increased over the last half century, suggesting a role for dietary factors. Fructose consumption has increased in recent years. Recently, a high fructose diet (HFrD) was shown to enhance DSS-induced colitis in mice. The primary objectives of the current study were to elucidate the mechanism(s) underlying the pro-colitic… Continue reading Dietary #Fructose Alters the Composition, Localization and Metabolism of Gut #Microbiota in Association with Worsening #Colitis
Cognitive Factors Associated with Frequency of #Eating Out and Eating Takeout among Latinas
Higher frequency of eating outside the home can be an unhealthy behavior that may contribute to higher rates of obesity among Latinas, a disproportionately affected group. There is a growing need to understand potentially modifiable factors (eg, dispositional mindfulness, self-efficacy, nutrition knowledge) associated with higher frequency of eating outside the home in this population. This… Continue reading Cognitive Factors Associated with Frequency of #Eating Out and Eating Takeout among Latinas
A Randomized Trial Comparing #Antibiotics with Appendectomy for #Appendicitis
..In total, 1552 adults (414 with an appendicolith) underwent randomization; 776 were assigned to receive antibiotics (47% of whom were not hospitalized for the index treatment) and 776 to undergo appendectomy (96% of whom underwent a laparoscopic procedure). Antibiotics were noninferior to appendectomy on the basis of 30-day EQ-5D scores (mean difference, 0.01 points; 95%… Continue reading A Randomized Trial Comparing #Antibiotics with Appendectomy for #Appendicitis
#SARS-CoV-2 Spike protein co-opts VEGF-A/Neuropilin-1 receptor signaling to induce #analgesia
Global spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues unabated. Binding of SARS-CoV-2’s Spike protein to host angiotensin converting enzyme 2 triggers viral entry, but other proteins may participate, including neuropilin-1 receptor (NRP-1). As both Spike protein and vascular endothelial growth factor-A (VEGF-A) – a pro-nociceptive and angiogenic factor, bind NRP-1, we tested… Continue reading #SARS-CoV-2 Spike protein co-opts VEGF-A/Neuropilin-1 receptor signaling to induce #analgesia
Association Between Time to Colonoscopy after Positive Fecal Testing and Colorectal Cancer Outcomes: a Systematic Review
Colonoscopy is required following a positive fecal screening test for colorectal cancer (CRC). It remains unclear to what extent time to colonoscopy is associated with CRC-related outcomes. We performed a systematic review to elucidate this relationship.. ..From 1,612 initial studies, 8 were included in the systematic review, with 5 reporting outcomes for FIT. Although meta-analysis… Continue reading Association Between Time to Colonoscopy after Positive Fecal Testing and Colorectal Cancer Outcomes: a Systematic Review
Effect of Face #Masks on Gas Exchange in Healthy Persons and Patients with #COPD
..In order to demonstrate the changes in end-tidal CO2 (ETCO2) and oxygen saturation (SpO2) before and after wearing a surgical mask, we used a convenience sample of 15 housestaff physicians without lung conditions (aged 31.1 1.9 years, 60% male) and 15 veterans with severe COPD (aged 71.6 8.7 years, FEV1 44.0 22.2%,… Continue reading Effect of Face #Masks on Gas Exchange in Healthy Persons and Patients with #COPD
#HPV Vaccination and the Risk of Invasive #Cervical Cancer
The efficacy and effectiveness of the quadrivalent human papillomavirus (HPV) vaccine in preventing high-grade cervical lesions have been shown. However, data to inform the relationship between quadrivalent HPV vaccination and the subsequent risk of invasive cervical cancer are lacking.. ..During the study period, we evaluated girls and women for cervical cancer until their 31st birthday.… Continue reading #HPV Vaccination and the Risk of Invasive #Cervical Cancer
The Importance of Cursive #Handwriting Over Typewriting for Learning in the Classroom: A High-Density #EEG Study of 12-Year-Old Children and Young Adults
To write by hand, to type, or to draw – which of these strategies is the most efficient for optimal learning in the classroom? As digital devices are increasingly replacing traditional writing by hand, it is crucial to examine the long-term implications of this practice. High-density electroencephalogram (HD EEG) was used in 12 young adults… Continue reading The Importance of Cursive #Handwriting Over Typewriting for Learning in the Classroom: A High-Density #EEG Study of 12-Year-Old Children and Young Adults
#ASPIRIN AND THE RISK OF NON‐DIGESTIVE TRACT CANCERS: AN UPDATED META‐ANALYSIS TO 2019
Aspirin has been associated to a reduced risk of colorectal and other selected digestive tract cancers, but the evidence other neoplasms is still controversial. In order to provide an up‐to‐date quantification of the role of aspirin on lung, breast, endometrium, ovary, prostate, bladder, and kidney cancer, we conducted a systematic review and meta‐analysis of all… Continue reading #ASPIRIN AND THE RISK OF NON‐DIGESTIVE TRACT CANCERS: AN UPDATED META‐ANALYSIS TO 2019
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