Efficacy of Single-Dose Human Papillomavirus Vaccination among Young African Women

BACKGROUNDSingle-dose human papillomavirus (HPV) vaccination, if efficacious, would be tremendously advantageous, simplifying implementation and decreasing costs. METHODSWe performed a randomized, multicenter, double-blind, controlled trial of single-dose nonavalent (HPV 16/18/31/33/45/52/58/6/11 infection) or bivalent (HPV 16/18 infection) HPV vaccination compared with meningococcal vaccination among Kenyan women 15 to 20 years of age. Enrollment and 6-monthly cervical swabs …

Continue reading Efficacy of Single-Dose Human Papillomavirus Vaccination among Young African Women

Dietary nutrient intake related to higher grade cervical intraepithelial neoplasia risk: a Chinese population-based study

BackgroundDietary nutrient intake plays a significant role in carcinogenesis. Few studies have investigated the association between dietary nutrient intake and cervical intraepithelial neoplasia (CIN) risk in China. MethodsData on 2304 women from an ongoing cohort comprising 40,000 women from China in 2014 were included. Study randomly selected 218 out of 2304 people as subjects during …

Continue reading Dietary nutrient intake related to higher grade cervical intraepithelial neoplasia risk: a Chinese population-based study

#HPV Vaccination and the Risk of Invasive #Cervical Cancer

The efficacy and effectiveness of the quadrivalent human papillomavirus (HPV) vaccine in preventing high-grade cervical lesions have been shown. However, data to inform the relationship between quadrivalent HPV vaccination and the subsequent risk of invasive cervical cancer are lacking.. ..During the study period, we evaluated girls and women for cervical cancer until their 31st birthday. …

Continue reading #HPV Vaccination and the Risk of Invasive #Cervical Cancer