Nitrites and nitrates occur naturally in water and soil and are commonly ingested from drinking water and dietary sources. They are also used as food additives, mainly in processed meats, to increase shelf life and to avoid bacterial growth. Experimental studies suggested both benefits and harmful effects of nitrites and nitrates exposure on type 2… Continue reading Dietary exposure to nitrites and nitrates in association with type 2 diabetes risk: Results from the NutriNet-Santé population-based cohort study
Guidelines of care for the management of atopic dermatitis in adults with topical therapies
BackgroundNew evidence has emerged since the 2014 guidelines that further informs the management of AD with topical therapies. These guidelines update the 2014 recommendations for management of atopic dermatitis (AD) with topical therapies.ObjectiveTo provide evidence-based recommendations related to management of AD in adults using topical treatments.MethodsA multidisciplinary workgroup conducted a systematic review and applied the… Continue reading Guidelines of care for the management of atopic dermatitis in adults with topical therapies
The gut microbiota in multiple sclerosis varies with disease activity
Multiple sclerosis is a chronic immune-mediated disease of the brain and spinal cord resulting in physical and cognitive impairment in young adults. It is hypothesized that a disrupted bacterial and viral gut microbiota is a part of the pathogenesis mediating disease impact through an altered gut microbiota-brain axis. The aim of this study is to… Continue reading The gut microbiota in multiple sclerosis varies with disease activity
The Association between Sugar-Sweetened Beverages and Male Pattern Hair Loss in Young Men
We performed this study to investigate the association between sugar-sweetened beverage (SSB) consumption and male pattern hair loss (MPHL) in young men. We conducted this cross-sectional study from January to April 2022 in mainland China. Young people aged 18–45 years (n = 1951) were recruited from 31 provinces in China. We used a self-reported online survey… Continue reading The Association between Sugar-Sweetened Beverages and Male Pattern Hair Loss in Young Men
Proton Pump Inhibitor Use and Risks of Cardiovascular Disease and Mortality in Patients With Type 2 Diabetes
Proton pump inhibitors (PPIs) are widely used drugs for gastric acid–related diseases and may affect the gut microbiome.ObjectiveWe aimed to evaluate the associations of PPI use with risks of cardiovascular disease (CVD) and all-cause mortality in patients with type 2 diabetes (T2D).MethodsWe analyzed the associations of PPI use with risks of coronary artery disease (CAD),… Continue reading Proton Pump Inhibitor Use and Risks of Cardiovascular Disease and Mortality in Patients With Type 2 Diabetes
Mask mandate and use efficacy for COVID-19 containment in US States
Background: COVID-19 pandemic mitigation requires evidence-based strategies. Because COVID-19 can spread via respired droplets, most US states mandated mask use in public settings. Randomized control trials have not clearly demonstrated mask efficacy against respiratory viruses, and observational studies conflict on whether mask use predicts lower infection rates. We hypothesized that statewide mask mandates and mask… Continue reading Mask mandate and use efficacy for COVID-19 containment in US States
Circulating Spike Protein Detected in Post–COVID-19 mRNA Vaccine Myocarditis
BACKGROUND:Cases of adolescents and young adults developing myocarditis after vaccination with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)–targeted mRNA vaccines have been reported globally, but the underlying immunoprofiles of these individuals have not been described in detail.METHODS:From January 2021 through February 2022, we prospectively collected blood from 16 patients who were hospitalized at Massachusetts General… Continue reading Circulating Spike Protein Detected in Post–COVID-19 mRNA Vaccine Myocarditis
Circulating Spike Protein Detected in Post–COVID-19 mRNA Vaccine Myocarditis
BACKGROUND:Cases of adolescents and young adults developing myocarditis after vaccination with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)–targeted mRNA vaccines have been reported globally, but the underlying immunoprofiles of these individuals have not been described in detail.METHODS:From January 2021 through February 2022, we prospectively collected blood from 16 patients who were hospitalized at Massachusetts General… Continue reading Circulating Spike Protein Detected in Post–COVID-19 mRNA Vaccine Myocarditis
Unravelling the role of the mandatory use of face covering masks for the control of SARS-CoV-2 in schools: a quasi-experimental study nested in a population-based cohort in Catalonia (Spain)
Objective To assess the effectiveness of mandatory use of face covering masks (FCMs) in schools during the first term of the 2021–2022 academic year.Design A retrospective population-based study.Setting Schools in Catalonia (Spain).Population 599 314 children aged 3–11 years attending preschool (3–5 years, without FCM mandate) and primary education (6–11 years, with FCM mandate).Study period From 13 September to 22 December 2021… Continue reading Unravelling the role of the mandatory use of face covering masks for the control of SARS-CoV-2 in schools: a quasi-experimental study nested in a population-based cohort in Catalonia (Spain)
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