Aims/hypothesisWe hypothesised that the insulin-sensitising effect of physical activity depends on the timing of the activity. Here, we examined cross-sectional associations of breaks in sedentary time and timing of physical activity with liver fat content and insulin resistance in a Dutch cohort.MethodsIn 775 participants of the Netherlands Epidemiology of Obesity (NEO) study, we assessed sedentary… Continue reading Timing of physical activity in relation to liver fat content and insulin resistance
Category: Sports
Causal analysis identifies small HDL particles and physical activity as key determinants of longevity of older adults
BackgroundThe hard endpoint of death is one of the most significant outcomes in both clinical practice and research settings. Our goal was to discover direct causes of longevity from medically accessible data.MethodsUsing a framework that combines local causal discovery algorithms with discovery of maximally predictive and compact feature sets (the “Markov boundaries” of the response)… Continue reading Causal analysis identifies small HDL particles and physical activity as key determinants of longevity of older adults
Prospective Associations of Daily Step Counts and Intensity With Cancer and Cardiovascular Disease Incidence and Mortality and All-Cause Mortality
Recommendations for the number of steps per day may be easier to enact for some people than the current time- and intensity-based physical activity guidelines, but the evidence to support steps-based goals is limited.Objective To describe the associations of step count and intensity with all-cause mortality and cancer and cardiovascular disease (CVD) incidence and mortality.Design, Setting,… Continue reading Prospective Associations of Daily Step Counts and Intensity With Cancer and Cardiovascular Disease Incidence and Mortality and All-Cause Mortality
Fitness tracking reveals task-specific associations between memory, mental health, and physical activity
Physical activity can benefit both physical and mental well-being. Different forms of exercise (e.g., aerobic versus anaerobic; running versus walking, swimming, or yoga; high-intensity interval training versus endurance workouts; etc.) impact physical fitness in different ways. For example, running may substantially impact leg and heart strength but only moderately impact arm strength. We hypothesized that… Continue reading Fitness tracking reveals task-specific associations between memory, mental health, and physical activity
Association of Daily Step Count and Intensity With Incident Dementia in 78 430 Adults Living in the UK
Key PointsQuestion Is there a dose-response association of daily step count and intensity with incidence of all-cause dementia among adults living in the UK?Findings This cohort study of adults assessed with wrist-worn accelerometers found that accruing more steps per day was associated with steady declines in dementia incidence risk, up to 9800 steps per day, beyond which… Continue reading Association of Daily Step Count and Intensity With Incident Dementia in 78 430 Adults Living in the UK
Association of Leisure Time Physical Activity Types and Risks of All-Cause, Cardiovascular, and Cancer Mortality Among Older Adults
Higher amounts of physical activity are associated with increased longevity. However, whether different leisure time physical activity types are differentially associated with mortality risk is not established.Objectives To examine whether participation in equivalent amounts of physical activity (7.5 to <15 metabolic equivalent of task [MET] hours per week) through different activity types is associated with… Continue reading Association of Leisure Time Physical Activity Types and Risks of All-Cause, Cardiovascular, and Cancer Mortality Among Older Adults
Low Daily Step Count Is Associated With a High Risk of Hospital Admission and Death in Community-Dwelling Patients With Cirrhosis
Background & AimsDaily step count measures cardiorespiratory fitness and has been associated with clinical outcomes. However, its utility in patients with cirrhosis remains largely unexplored. We aimed to investigate the association between step count, frailty metrics, and clinical outcomes in cirrhosis.MethodsAll participants underwent frailty evaluation with the liver frailty index, 6-minute walk test, and gait… Continue reading Low Daily Step Count Is Associated With a High Risk of Hospital Admission and Death in Community-Dwelling Patients With Cirrhosis
Physical activity, diet quality and all-cause cardiovascular disease and cancer mortality: a prospective study of 346 627 UK Biobank participants
AbstractObjectives To examine independent and interactive associations of physical activity and diet with all-cause, cardiovascular disease (CVD) and physical activity, diet and adiposity-related (PDAR) cancer mortality.Methods This population-based prospective cohort study (n=346 627) is based on the UK Biobank data with linkage to the National Health Service death records to 30 April 2020. A left-truncated Cox… Continue reading Physical activity, diet quality and all-cause cardiovascular disease and cancer mortality: a prospective study of 346 627 UK Biobank participants
Higher protein intake during caloric restriction improves diet quality and attenuates loss of lean body mass
ObjectiveHigher protein intake during weight loss is associated with better health outcomes, but whether this is because of improved diet quality is not known. The purpose of this study was to examine how the change in self-selected protein intake during caloric restriction (CR) alters diet quality and lean body mass (LBM). MethodsIn this analysis of… Continue reading Higher protein intake during caloric restriction improves diet quality and attenuates loss of lean body mass
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