The relationship of depressive symptoms with kidney function remains poorly investigated. We aimed to evaluate the prospective association between depressive symptoms and rapid decline in kidney function in Chinese adults with normal kidney function. Design, setting, participants, & measurements A total of 4763 participants with eGFR≥60 ml/min per 1.73 m2 at baseline were enrolled from… Continue reading Association of #Depressive Symptoms with Rapid #Kidney Function Decline in Adults with Normal Kidney Function
Category: Psychiatry
Effect of Extended-Release #Naltrexone on #Alcohol Consumption: A Systematic Review and Meta-analysis
Aims1) Estimate the effect of extended-release naltrexone compared with placebo on alcohol consumption in patients with alcohol use disorder (AUD). 2) Conduct pre-planned subgroup analyses to test whether being abstinent when initiating treatment (lead-in abstinence) or the duration of treatment improves treatment efficacy. DesignSystematic review and random effects meta-analysis of blinded randomized placebo-controlled trials reporting… Continue reading Effect of Extended-Release #Naltrexone on #Alcohol Consumption: A Systematic Review and Meta-analysis
Increased #Risk of Stroke in Patients With #Obsessive-Compulsive Disorder: A Nationwide Longitudinal Study
Patients with obsessive-compulsive disorder (OCD) tend to be comorbid with stroke-related risk factors, including obesity, hypertension, and diabetes. However, the temporal association between OCD and subsequent stroke risk is unclear. Methods:Using data collected between 2001 and 2010 by Taiwan’s National Health Insurance Research Database, 28 064 adult patients with OCD (International Classification of Diseases, Ninth… Continue reading Increased #Risk of Stroke in Patients With #Obsessive-Compulsive Disorder: A Nationwide Longitudinal Study
Genetically Proxied Diurnal Preference, #Sleep Timing, and Risk of Major #Depressive Disorder
Morning diurnal preference is associated with reduced risk of major depressive disorder (MDD); however, causality in this association is uncertain. Objective To examine the association of genetically proxied morning diurnal preference with depression risk using mendelian randomization. Design, Setting, and Participants This 2-sample mendelian randomization study used summary-level genetic associations with diurnal preference and MDD.… Continue reading Genetically Proxied Diurnal Preference, #Sleep Timing, and Risk of Major #Depressive Disorder
#Cognitive Behavioral Approach to Treat #Obesity: A Randomized Clinical Trial
Our aim was to analyze and compare the effects of three different long-term treatments on anthropometric profiles, eating behaviors, anxiety and depression levels, and quality of life of groups of adults with obesity. Methods: The 43 participants in the study were randomly assigned to one of three groups: the education and health group (EH, n… Continue reading #Cognitive Behavioral Approach to Treat #Obesity: A Randomized Clinical Trial
Dynamic Associations Between #Anxiety, #Depression, and #Tobacco Use in Older Adults: Results From The Irish Longitudinal Study on Ageing
Evidence supports moderate-to-large reductions in anxiety, depression, and perceived stress after smoking cessation; however, much of the available evidence has focused on young adults. Therefore, this study quantified associations between smoking and smoking cessation on prevalent and incident generalised anxiety disorder (GAD) and major depression (MDD) in a nationally representative sample of Irish older adults.… Continue reading Dynamic Associations Between #Anxiety, #Depression, and #Tobacco Use in Older Adults: Results From The Irish Longitudinal Study on Ageing
Association of #Mitochondrial Biogenesis With Variable Penetrance of #Schizophrenia
Discovery of mechanisms that underlie variable penetrance for neuropsychiatric illness in the context of genetic variants that carry elevated risk can advance novel treatment approaches for these disorders. Objective To test the hypothesis that mitochondrial compensation is associated with the variable penetrance of schizophrenia in the 22q11.2 deletion syndrome (22q11DS). Design, Setting, and Participants This… Continue reading Association of #Mitochondrial Biogenesis With Variable Penetrance of #Schizophrenia
Clinical outcomes in a large registry of patients with major #depressive disorder treated with Transcranial #Magnetic Stimulation
Clinical outcomes were examined in the largest registry of patients treated for an episode of major depressive disorder. •The registry included more than more than 5,000 patients treated with TMS at more than 100 private practice sites. •Self-report and clinician ratings showed robust antidepressant effects, greater than those in the early studies of TMS. •Efficacy… Continue reading Clinical outcomes in a large registry of patients with major #depressive disorder treated with Transcranial #Magnetic Stimulation
The #COVID-19 #anxiety syndrome scale: Development and psychometric properties
The central aim of our study was to widen the mental health response to the COVID-19 pandemic by developing and evaluating a measure that could be used to identify the presence of anxiety syndrome features associated with COVID-19. In Study 1, a community sample of 292 participants completed the newly developed COVID-19 Anxiety Syndrome Scale… Continue reading The #COVID-19 #anxiety syndrome scale: Development and psychometric properties
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