#Social Health and #Cardiovascular Disease Risk Factors: A cross-sectional study in a healthy older adult population

Poor social health is a risk factor for cardiovascular disease (CVD), however an in-depth exploration of the link through CVD risk factors is lacking. AimTo examine the relationship between social health (social isolation, social support, loneliness) and CVD risk factors among healthy older women and men. MethodsData were from 11,498 healthy community-dwelling Australians aged ≥70… Continue reading #Social Health and #Cardiovascular Disease Risk Factors: A cross-sectional study in a healthy older adult population

The temporal representation of #experience in subjective #mood

Humans refer to their mood state regularly in day-to-day as well as clinical interactions. Theoretical accounts suggest that when reporting on our mood we integrate over the history of our experiences; yet, the temporal structure of this integration remains unexamined. Here, we use a computational approach to quantitatively answer this question and show that early… Continue reading The temporal representation of #experience in subjective #mood

A phase 2 trial of inhaled #nitrous oxide for treatment-resistant major #depression

Laughing gas improves depressionAbout one-third of individuals suffering from depression are at risk for treatment resistance. Whereas inhaled 50% nitrous oxide has early antidepressant effects on individuals with treatment-resistant major depression (TRMD), adverse effects can occur at this concentration. In this phase 2 clinical trial, Nagele et al. studied the effects of a single 1-hour… Continue reading A phase 2 trial of inhaled #nitrous oxide for treatment-resistant major #depression

#Aggressive incidents in #psychiatric hospitals on #heat days

This study explores the relationship between temperature and the number of aggressive incidents and coercive interventions in the years 2007–2019 in six psychiatric hospitals in the south of the Germany with a total of 1007 beds. The number of aggressive incidents among 164 435 admissions was significantly higher on ‘heat days’ (≥30°C). Furthermore, there was… Continue reading #Aggressive incidents in #psychiatric hospitals on #heat days

Reduced adaptation of glutamatergic #stress response is associated with #pessimistic expectations in #depression

Stress is a significant risk factor for the development of major depressive disorder (MDD), yet the underlying mechanisms remain unclear. Preclinically, adaptive and maladaptive stress-induced changes in glutamatergic function have been observed in the medial prefrontal cortex (mPFC). Here, we examine stress-induced changes in human mPFC glutamate using magnetic resonance spectroscopy (MRS) in two healthy… Continue reading Reduced adaptation of glutamatergic #stress response is associated with #pessimistic expectations in #depression

Selective serotonin reuptake inhibitors, and serotonin and norepinephrine reuptake inhibitors for #anxiety, #obsessive-compulsive, and #stress disorders: A 3-level network meta-analysis

Anxiety, obsessive-compulsive, and stress-related disorders frequently co-occur, and patients often present symptoms of several domains. Treatment involves the use of selective serotonin reuptake inhibitors (SSRIs) and serotonin and norepinephrine reuptake inhibitors (SNRIs), but data on comparative efficacy and acceptability are lacking. We aimed to compare the efficacy of SSRIs, SNRIs, and placebo in multiple symptom… Continue reading Selective serotonin reuptake inhibitors, and serotonin and norepinephrine reuptake inhibitors for #anxiety, #obsessive-compulsive, and #stress disorders: A 3-level network meta-analysis

Bedtime #Music, Involuntary Musical Imagery, and #Sleep

Many people listen to music for hours every day, often near bedtime. We investigated whether music listening affects sleep, focusing on a rarely explored mechanism: involuntary musical imagery (earworms). In Study 1 (N = 199, mean age = 35.9 years), individuals who frequently listen to music reported persistent nighttime earworms, which were associated with worse… Continue reading Bedtime #Music, Involuntary Musical Imagery, and #Sleep

Sex differences in risk factors for #depressive symptoms in patients with #COPD: The 2014 and 2016 Korea National Health and Nutrition Examination Survey

Although depression is a common comorbidity of chronic obstructive pulmonary disease (COPD), the role of sex remains unexplored. We evaluated sex differences of risk factors of depressive symptoms in adults with COPD. MethodsThis was a population-based cross-sectional study using data from the 2014 and 2016 Korea National Health and Nutrition Examination Survey. Spirometry was used… Continue reading Sex differences in risk factors for #depressive symptoms in patients with #COPD: The 2014 and 2016 Korea National Health and Nutrition Examination Survey

The impact of #caffeine consumption on clinical symptoms in patients with #bipolar disorder: A systematic review

In healthy populations, caffeine appears to have beneficial effects on health; however, patients with bipolar disorder (BD) are routinely advised to limit caffeine use in psychoeducation programmes. We aimed to examine all literature reporting whether caffeine intake/withdrawal impacts the natural course of BD, in terms of clinical outcomes. MethodsPubMed, Embase and PsycINFO were searched (up… Continue reading The impact of #caffeine consumption on clinical symptoms in patients with #bipolar disorder: A systematic review