Association of #Mitochondrial Biogenesis With Variable Penetrance of #Schizophrenia

Discovery of mechanisms that underlie variable penetrance for neuropsychiatric illness in the context of genetic variants that carry elevated risk can advance novel treatment approaches for these disorders. Objective To test the hypothesis that mitochondrial compensation is associated with the variable penetrance of schizophrenia in the 22q11.2 deletion syndrome (22q11DS). Design, Setting, and Participants This …

Continue reading Association of #Mitochondrial Biogenesis With Variable Penetrance of #Schizophrenia