Musicianship can mitigate age-related declines in audiovisual speech-in-noise perception. We tested whether this benefit originates from functional preservation or functional compensation by comparing fMRI responses of older musicians, older nonmusicians, and young nonmusicians identifying noise-masked audiovisual syllables. Older musicians outperformed older nonmusicians and showed comparable performance to young nonmusicians. Notably, older musicians retained similar neural… Continue reading Successful aging of musicians: Preservation of sensorimotor regions aids audiovisual speech-in-noise perception
Category: Neurology
Impaired muscle function, including its decline, is related to greater long-term late-life dementia risk in older women
AbstractBackgroundImpaired muscle function has been identified as a risk factor for declining cognitive function and cardiovascular health, both of which are risk factors for late-life dementia (after 80 years of age). We examined whether hand grip strength and timed-up-and-go (TUG) performance, including their change over 5 years, were associated with late-life dementia events in older women and… Continue reading Impaired muscle function, including its decline, is related to greater long-term late-life dementia risk in older women
Sex Hormones and Calcitonin Gene–Related Peptide in Women With MigraineA Cross-sectional, Matched Cohort Study
Background and Objectives Sex hormones may modulate calcitonin gene-related peptide (CGRP) release in the trigeminovascular system. We studied CGRP concentrations in plasma and tear fluid in female participants with episodic migraine (EM) and a regular menstrual cycle (RMC), female participants with EM and combined oral contraception (COC), and female participants with EM in the postmenopause.… Continue reading Sex Hormones and Calcitonin Gene–Related Peptide in Women With MigraineA Cross-sectional, Matched Cohort Study
Effect of walnut consumption on neuropsychological development in healthy adolescents: a multi-school randomised controlled trial
BackgroundOmega-3 fatty acids are critical for neuropsychological functioning. Adolescence is increasingly believed to entail brain vulnerability to dietary intake. The potential benefit on adolescent neurodevelopment of consuming walnuts, a source of omega-3 alpha-linolenic acid (ALA), remains unclear.MethodsWe conducted a 6-month multi-school-based randomised controlled nutrition intervention trial to assess whether walnut consumption has beneficial effects on… Continue reading Effect of walnut consumption on neuropsychological development in healthy adolescents: a multi-school randomised controlled trial
Migraine Headaches in Patients with Upper Extremity Compressive Neuropathy
Background: Upper extremity nerve compression syndromes and migraines caused by nerve entrapment have many similarities, including patient presentation, anatomical findings, and treatment by surgical decompression of affected nerves. Parallels between the two conditions point toward the possibility of shared predisposition. The aim of this study was to evaluate the relationship between migraine and upper extremity… Continue reading Migraine Headaches in Patients with Upper Extremity Compressive Neuropathy
Dietary sugar consumption and health: umbrella review
Objective To evaluate the quality of evidence, potential biases, and validity of all available studies on dietary sugar consumption and health outcomes.Design Umbrella review of existing meta-analyses.Data sources PubMed, Embase, Web of Science, Cochrane Database of Systematic Reviews, and hand searching of reference lists.Inclusion criteria Systematic reviews and meta-analyses of randomised controlled trials, cohort studies,… Continue reading Dietary sugar consumption and health: umbrella review
Caffeine consumption as a risk factor for childhood and adolescence migraine
Background: Caffeine consumption is a risk factor for chronic daily headache but few studies have addressed relationships between pediatric patient caffeine levels and headache severity. We examined associations between serum and urine caffeine levels and headache severity in childhood and adolescent migraine cases.Methods: Levels of caffeine and caffeine metabolites in serum and urine samples were… Continue reading Caffeine consumption as a risk factor for childhood and adolescence migraine
Association of Early Adulthood Hypertension and Blood Pressure Change With Late-Life Neuroimaging Biomarkers
The association between hypertension developed before midlife and late-life brain health is understudied and, because of the cardioprotective benefits of estrogen before menopause, may differ by sex. Objective To assess the association of early adulthood hypertension and blood pressure (BP) change with late-life neuroimaging biomarkers and examine potential sex differences. Design, Setting, and Participants This cohort study… Continue reading Association of Early Adulthood Hypertension and Blood Pressure Change With Late-Life Neuroimaging Biomarkers
Sleep Patterns and the Risk of Acute Stroke: Results from the INTERSTROKE International Case-Control Study
Background and Objectives: Symptoms of sleep disturbance are common, and may represent important modifiable risk factors for stroke. We evaluated the association between a spectrum of sleep disturbance symptoms and risk of acute stroke in an international setting.Methods: INTERSTROKE is an international case-control study of patients presenting with first acute stroke and controls matched by… Continue reading Sleep Patterns and the Risk of Acute Stroke: Results from the INTERSTROKE International Case-Control Study
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