To prevent diabetic complications, strict glucose control and frequent monitoring of blood glucose levels are necessary. However, all currently available methods for blood glucose monitoring, including the finger prick method, are invasive. Therefore, noninvasive blood glucose monitoring approaches have been investigated, but until date, none has been found to be a suitable substitute for direct… Continue reading 644 – Development of noninvasive #diabetes monitoring method using #tear samples
Category: Endocrinology
#Life Expectancy after #Bariatric Surgery in the Swedish Obese Subjects Study
Obesity shortens life expectancy. Bariatric surgery is known to reduce the long-term relative risk of death, but its effect on life expectancy is unclear.. ..In total, 2007 and 2040 patients were included in the surgery group and the control group, respectively, and 1135 participants were included in the reference cohort. At the time of the… Continue reading #Life Expectancy after #Bariatric Surgery in the Swedish Obese Subjects Study
#Dapagliflozin in Patients with Chronic #Kidney Disease
Patients with chronic kidney disease have a high risk of adverse kidney and cardiovascular outcomes. The effect of dapagliflozin in patients with chronic kidney disease, with or without type 2 diabetes, is not known.. ..The independent data monitoring committee recommended stopping the trial because of efficacy. Over a median of 2.4 years, a primary outcome… Continue reading #Dapagliflozin in Patients with Chronic #Kidney Disease
Trends in #Adiposity and #Food Insecurity Among US Adults
..Food insecurity is a core indicator of nutritional status and “exists whenever the availability of nutritionally adequate and safe foods or the ability to acquire acceptable foods in socially acceptable ways is limited or uncertain.” ..Main Outcomes and Measures The primary outcome was food insecurity. Data on BMI (calculated as weight in kilograms divided by… Continue reading Trends in #Adiposity and #Food Insecurity Among US Adults
Once-Weekly #Insulin for Type 2 #Diabetes without Previous Insulin Treatment
It is thought that a reduction in the frequency of basal insulin injections might facilitate treatment acceptance and adherence among patients with type 2 diabetes. Insulin icodec is a basal insulin analogue designed for once-weekly administration that is in development for the treatment of diabetes We conducted a 26-week, randomized, double-blind, double-dummy, phase 2 trial… Continue reading Once-Weekly #Insulin for Type 2 #Diabetes without Previous Insulin Treatment
#Loneliness and type 2 #diabetes incidence: findings from the English Longitudinal Study of Ageing
Loneliness is associated with all-cause mortality and coronary heart disease. However, the prospective relationship between loneliness and type 2 diabetes onset is unclear.. ..A total of 264 (6.42%) participants developed type 2 diabetes over the follow-up period. Loneliness was a significant predictor of incident type 2 diabetes (HR 1.46; 95% CI 1.15, 1.84; p = 0.002) independent… Continue reading #Loneliness and type 2 #diabetes incidence: findings from the English Longitudinal Study of Ageing
Associations of #BMI and Serum #Urate with Developing #Dementia: A Prospective Cohort Study
Recent studies suggested that higher BMI and serum urate levels were associated with lower risk of developing dementia. However, these reverse relationships remain controversial, and whether serum urate and BMI confound each other is not well established.. ..During a median of 8.1 years of follow-up, a total of 2138 participants developed dementia. People who were… Continue reading Associations of #BMI and Serum #Urate with Developing #Dementia: A Prospective Cohort Study
An atlas on risk factors for type 2 #diabetes: a wide-angled Mendelian randomisation study
..We found evidence of causal associations between 34 exposures (19 risk factors and 15 protective factors) and type 2 diabetes. Insomnia was identified as a novel risk factor (OR 1.17 [95% CI 1.11, 1.23]). The other 18 risk factors were depression, systolic BP, smoking initiation, lifetime smoking, coffee (caffeine) consumption, plasma isoleucine, valine and leucine,… Continue reading An atlas on risk factors for type 2 #diabetes: a wide-angled Mendelian randomisation study
#Obesity Has a Stronger Relationship with Colorectal #Cancer in Postmenopausal Women Than Premenopausal Women
Background: To examine the relationship between obesity measured by waist circumference (WC) and body mass index (BMI) and the incidence of colorectal cancer (CRC) in premenopausal and postmenopausal women. Methods: A total of 1,418,180 premenopausal and 4,854,187 postmenopausal women without cancer at baseline and aged over 40 were identified using the Korean National Health Insurance… Continue reading #Obesity Has a Stronger Relationship with Colorectal #Cancer in Postmenopausal Women Than Premenopausal Women
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