Objectives The Salt Substitute and Stroke Study (SSaSS) recently reported blood pressure-mediated benefits of a potassium-enriched salt substitute on cardiovascular outcomes and death. This study assessed the effects of salt substitutes on a breadth of outcomes to quantify the consistency of the findings and understand the likely generalisability of the SSaSS results.Methods We searched PubMed,… Continue reading Effects of salt substitutes on clinical outcomes: a systematic review and meta-analysis
Category: Diet
Rapidly Increasing Serum 25(OH)D Boosts the Immune System, against Infections—Sepsis and COVID-19
Vitamin D deficiency is a global public health problem, a pandemic that commonly affects the elderly and those with comorbidities such as obesity, diabetes, hypertension, respiratory disorders, recurrent infections, immune deficiency, and malignancies, as well as ethnic minorities living in temperate countries. The same groups were worst affected by COVID-19. Since vitamin D deficiency weakens… Continue reading Rapidly Increasing Serum 25(OH)D Boosts the Immune System, against Infections—Sepsis and COVID-19
High-dose Vitamin B6 supplementation reduces anxiety and strengthens visual surround suppression
ObjectiveVitamins B6 and B12 are involved in metabolic processes that decrease neural excitation and increase inhibition. This double-blind study investigated the effects of supplementation for 1 month with a high-dose of B6 or B12, compared to placebo, on a range of behavioural outcome measures connected to the balance between neural inhibition and excitation.Methods478 young adults… Continue reading High-dose Vitamin B6 supplementation reduces anxiety and strengthens visual surround suppression
Risk of fractures and subsequent mortality in alcohol-related cirrhosis: A nationwide population-based cohort study
Background and aimsAlcohol-related cirrhosis is linked to increased risk of fractures, but this has seldom been quantified nationally or compared against non-cirrhotic controls. Here, we determined the rate and risk of fractures and post-fracture mortality in patients with alcohol-related cirrhosis compared to individuals from the general population.MethodsIn this nationwide population-based cohort study, data were retrieved… Continue reading Risk of fractures and subsequent mortality in alcohol-related cirrhosis: A nationwide population-based cohort study
Sex-specific associations between potassium intake, blood pressure, and cardiovascular outcomes: the EPIC-Norfolk study
AimsA potassium replete diet is associated with lower blood pressure (BP) and lower risk of cardiovascular disease (CVD). Whether these associations differ between men and women and whether they depend on daily sodium intake is unknown.Methods and resultsAn analysis was performed in 11 267 men and 13 696 women from the EPIC-Norfolk cohort. Twenty-four hour excretion of… Continue reading Sex-specific associations between potassium intake, blood pressure, and cardiovascular outcomes: the EPIC-Norfolk study
Eating Disorder Diagnoses in Children and Adolescents in Norway Before vs During the COVID-19 Pandemic
Studies from the US1,2 and Canada3,4 have reported increasing numbers of children and adolescents receiving treatment for eating disorders during the COVID-19 pandemic. Most patients are girls,1,2,4 and the predominant diagnosis is anorexia nervosa.1,2 There is insufficient information about the magnitude of this increase on a population level. In this cohort study, we analyzed trends… Continue reading Eating Disorder Diagnoses in Children and Adolescents in Norway Before vs During the COVID-19 Pandemic
High-dose Vitamin B6 supplementation reduces anxiety and strengthens visual surround suppression
ObjectiveVitamins B6 and B12 are involved in metabolic processes that decrease neural excitation and increase inhibition. This double-blind study investigated the effects of supplementation for 1 month with a high-dose of B6 or B12, compared to placebo, on a range of behavioural outcome measures connected to the balance between neural inhibition and excitation.Methods478 young adults… Continue reading High-dose Vitamin B6 supplementation reduces anxiety and strengthens visual surround suppression
Physical activity, diet quality and all-cause cardiovascular disease and cancer mortality: a prospective study of 346 627 UK Biobank participants
AbstractObjectives To examine independent and interactive associations of physical activity and diet with all-cause, cardiovascular disease (CVD) and physical activity, diet and adiposity-related (PDAR) cancer mortality.Methods This population-based prospective cohort study (n=346 627) is based on the UK Biobank data with linkage to the National Health Service death records to 30 April 2020. A left-truncated Cox… Continue reading Physical activity, diet quality and all-cause cardiovascular disease and cancer mortality: a prospective study of 346 627 UK Biobank participants
Effect of Incorporating 1 Avocado Per Day Versus Habitual Diet on Visceral Adiposity: A Randomized Trial
AbstractBackgroundExcess visceral adiposity is associated with increased risk of cardiometabolic disorders. Short‐term well‐controlled clinical trials suggest that regular avocado consumption favorably affects body weight, visceral adiposity, and satiety.Methods and ResultsThe HAT Trial (Habitual Diet and Avocado Trial) was a multicenter, randomized, controlled parallel‐arm trial designed to test whether consuming 1 large avocado per day for… Continue reading Effect of Incorporating 1 Avocado Per Day Versus Habitual Diet on Visceral Adiposity: A Randomized Trial
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