Nature’s Pharmacy: Common Plants With Medicinal Properties

Throughout history, the use of plants for medicinal purposes has been a cornerstone in various cultures around the world. This age-old practice, deeply rooted in traditional knowledge, has seen a revival in recent years, as more people seek natural alternatives for health and wellness. Nature’s pharmacy is not just a trend; it’s supported by a… Continue reading Nature’s Pharmacy: Common Plants With Medicinal Properties

OXR1 maintains the retromer to delay brain #aging under #dietary restriction

Dietary restriction (DR) delays aging, but the mechanism remains unclear. We identified polymorphisms in mtd, the fly homolog of OXR1, which influenced lifespan and mtd expression in response to DR. Knockdown in adulthood inhibited DR-mediated lifespan extension in female flies. We found that mtd/OXR1 expression declines with age and it interacts with the retromer, which regulates trafficking of proteins and lipids.… Continue reading OXR1 maintains the retromer to delay brain #aging under #dietary restriction

Consumption of 100% Fruit #Juice and Body #Weight in Children and AdultsA Systematic Review and Meta-Analysis

Importance  Concerns have been raised that frequent consumption of 100% fruit juice may promote weight gain. Current evidence on fruit juice and weight gain has yielded mixed findings from both observational studies and clinical trials.Objective  To synthesize the available evidence on 100% fruit juice consumption and body weight in children and adults.Data Sources  MEDLINE, Embase, and Cochrane databases… Continue reading Consumption of 100% Fruit #Juice and Body #Weight in Children and AdultsA Systematic Review and Meta-Analysis

Association between #tomato consumption and #blood pressure in an older population at high cardiovascular risk: observational analysis of PREDIMED trial

Clinical studies have produced conflicting evidence on the effects of the consumption of tomatoes on blood pressure, and there are limited data from epidemiologic studies. This study assesses whether tomato consumption (Solanum lycopersicum L.) is associated with systolic and diastolic blood pressure, and the risk of hypertension in a prospective 3-year longitudinal study in older adults… Continue reading Association between #tomato consumption and #blood pressure in an older population at high cardiovascular risk: observational analysis of PREDIMED trial

Association between diet soft #drink consumption and #metabolic dysfunction-associated #steatotic liver disease: findings from the NHANES

Lifestyle change plays a crucial role in the prevention and treatment of metabolic dysfunction-associated steatotic liver disease (MASLD). In recent years, diet soft drinks that emphasize “zero sugar and zero calories” have become all the rage, but whether diet soft drink consumption is associated with MASLD is not clear.MethodsThis study included data from the National… Continue reading Association between diet soft #drink consumption and #metabolic dysfunction-associated #steatotic liver disease: findings from the NHANES

Examining the Association between #Coffee Intake and the Risk of Developing #Irritable #Bowel Syndrome: A Systematic Review and Meta-Analysis

Abstract: Irritable bowel syndrome (IBS) is a highly prevalent disorder of brain­gut interaction with a significant impact on quality of life. Coffee is a widely consumed beverage with numerous bioactive compounds that have potential effects on human health and disease states. Current studies on the effect of regular coffee consumption on the risk of developing… Continue reading Examining the Association between #Coffee Intake and the Risk of Developing #Irritable #Bowel Syndrome: A Systematic Review and Meta-Analysis

Enhancing Vision: Exploring the Link Between Vitamin #C and Reduced #Cataract Risks – A Physician’s Perspective

As physicians continually explore avenues for promoting overall health, recent research has shed light on a potential ally in the fight against cataracts – Vitamin C. This essential nutrient, long celebrated for its immune-boosting properties, is now gaining recognition for its potential role in reducing the risk of cataract development. In this blog post, I… Continue reading Enhancing Vision: Exploring the Link Between Vitamin #C and Reduced #Cataract Risks – A Physician’s Perspective

Vitamin #B12 is a limiting factor for induced cellular plasticity and #tissue repair

Transient reprogramming by the expression of OCT4, SOX2, KLF4 and MYC (OSKM) is a therapeutic strategy for tissue regeneration and rejuvenation, but little is known about its metabolic requirements. Here we show that OSKM reprogramming in mice causes a global depletion of vitamin B12 and molecular hallmarks of methionine starvation. Supplementation with vitamin B12 increases the efficiency… Continue reading Vitamin #B12 is a limiting factor for induced cellular plasticity and #tissue repair

Multi-omic network analysis identified #betacellulin as a novel target of #omega-3 fatty acid attenuation of western diet-induced nonalcoholic #steatohepatitis

Clinical and preclinical studies established that supplementing diets with ω3 polyunsaturated fatty acids (PUFA) can reduce hepatic dysfunction in nonalcoholic steatohepatitis (NASH) but molecular underpinnings of this action were elusive. Herein, we used multi-omic network analysis that unveiled critical molecular pathways involved in ω3 PUFA effects in a preclinical mouse model of western diet induced… Continue reading Multi-omic network analysis identified #betacellulin as a novel target of #omega-3 fatty acid attenuation of western diet-induced nonalcoholic #steatohepatitis