Several studies have linked adverse health effects to the consumption of ultra-processed foods (UPF) according to the NOVA classification. However, whether the consumption of UPF is the actual causal factor for such health outcomes is still unknown. Indeed, different groups of UPF examined in the same epidemiologic study often show markedly different associations with the… Continue reading #Ultra-processed foods and health: are we correctly interpreting the available evidence?
Category: Diet
Brazil #Nut (Bertholletia excelsa H.B.K.) Consumption in Energy-Restricted Intervention Decreases Proinflammatory Markers and #Intestinal Permeability of Women with Overweight/Obesity: A Controlled Trial (Brazilian Nuts Study)
BackgroundObesity is associated with low-grade inflammation and increased intestinal permeability (IP). The Brazil nut (BN) (Bertholletia excelsa H.B.K.) appears to be a promising dietary intervention to control inflammation by enhancing antioxidant defenses.ObjectivesWe aimed to assess the effect of daily BN consumption on inflammatory biomarkers and IP in the context of an energy-restricted intervention. Furthermore, we… Continue reading Brazil #Nut (Bertholletia excelsa H.B.K.) Consumption in Energy-Restricted Intervention Decreases Proinflammatory Markers and #Intestinal Permeability of Women with Overweight/Obesity: A Controlled Trial (Brazilian Nuts Study)
Modifiers of the Effects of Vitamin #D Supplementation on #Cardiometabolic Risk Factors: A Systematic Review and Meta-Analysis
The inconsistent findings concerning the effects of vitamin D supplementation on cardiometabolic risk factors and the large heterogeneity in the published literature call for further research to identify sources of heterogeneity and potential effect modifiers. We performed a meta-analysis of randomized controlled trials (RCTs) published until March 2024 that reported estimates for the effects of… Continue reading Modifiers of the Effects of Vitamin #D Supplementation on #Cardiometabolic Risk Factors: A Systematic Review and Meta-Analysis
Effect of matcha green #tea on #cognitive functions and #sleep quality in older adults with cognitive decline: A randomized controlled study over 12 months
Lifestyle habits after middle age significantly impact the maintenance of cognitive function in older adults. Nutritional intake is closely related to lifestyle habits; therefore, nutrition is a pivotal factor in the prevention of dementia in the preclinical stages. Matcha green tea powder (matcha), which contains epigallocatechin gallate, theanine, and caffeine, has beneficial effects on cognitive… Continue reading Effect of matcha green #tea on #cognitive functions and #sleep quality in older adults with cognitive decline: A randomized controlled study over 12 months
#Lignan Intake and Type 2 #Diabetes Incidence Among US Men and Women
Importance Lignans are phytoestrogens abundant in Western diets and may be associated with type 2 diabetes (T2D) risk.Objective To prospectively investigate associations between lignan intake and T2D incidence.Design, Setting, and Participants Population-based cohort study of US men and women enrolled in the Nurses’ Health Study (NHS, 1984-2018), NHSII (1991-2019), and Health Professionals Follow-Up Study (HPFS, 1986-2020), as well… Continue reading #Lignan Intake and Type 2 #Diabetes Incidence Among US Men and Women
Estimated Exposure to 6 Potentially #Hepatotoxic Botanicals in US Adults
Importance Use of herbal and dietary supplements (HDSs) accounts for an increasing proportion of drug hepatotoxicity cases. Turmeric or curcumin, green tea extract, Garcinia cambogia, black cohosh, red yeast rice, and ashwagandha are the most frequently reported hepatoxic botanicals, but their prevalence and reasons for use in the general population are unknown.Objective To assess the prevalence and clinical… Continue reading Estimated Exposure to 6 Potentially #Hepatotoxic Botanicals in US Adults
ω-3 #PUFA for Secondary Prevention of White Matter Lesions and Neuronal Integrity Breakdown in Older AdultsA Randomized Clinical Trial
Importance Older adults with lower intake and tissue levels of long-chain ω-3 polyunsaturated fatty acids (PUFAs) eicosapentaenoic acid (EPA; 20:5) and docosahexaenoic acid (DHA; 22:6) have more brain white matter lesions (WMLs), an association suggesting that small-vessel ischemic disease, a major contributor to the development of dementia, including Alzheimer disease, may be preventable through ω-3 treatment.Objective To… Continue reading ω-3 #PUFA for Secondary Prevention of White Matter Lesions and Neuronal Integrity Breakdown in Older AdultsA Randomized Clinical Trial
Higher #Coffee Consumption Is Associated With Slower #Cognitive Decline and Less Cerebral Aβ-Amyloid Accumulation Over 126 Months: Data From the Australian Imaging, Biomarkers, and Lifestyle Study
AbstractBackground: Worldwide, coffee is one of the most popular beverages consumed. Several studies have suggested a protective role of coffee, including reduced risk of Alzheimer's disease (AD). However, there is limited longitudinal data from cohorts of older adults reporting associations of coffee intake with cognitive decline, in distinct domains, and investigating the neuropathological mechanisms underpinning any… Continue reading Higher #Coffee Consumption Is Associated With Slower #Cognitive Decline and Less Cerebral Aβ-Amyloid Accumulation Over 126 Months: Data From the Australian Imaging, Biomarkers, and Lifestyle Study
Brain responses to intermittent #fasting and the healthy living #diet in older adults
Highlights•8 weeks of 5:2 intermittent fasting caused more weight loss than healthy living diet•Both diets reduced neuronal insulin resistance and the pace of brain aging•Both diets improved memory and executive function, with 5:2 intermittent fasting more so•Biomarkers of Alzheimer’s disease did not change with either dietSummaryDiet may promote brain health in metabolically impaired older individuals. In… Continue reading Brain responses to intermittent #fasting and the healthy living #diet in older adults
