Opting for olive oil could boost brain healthRegular olive oil consumption associated with 28% lower risk of fatal dementia

oil as part of a Mediterranean dietary pattern has also been shown to help protect against cognitive decline. Tessier cautioned that the research is observational and does not prove that olive oil is the cause of the reduced risk of fatal dementia. Additional studies such as randomized controlled trials would be needed to confirm the effects… Continue reading Opting for olive oil could boost brain healthRegular olive oil consumption associated with 28% lower risk of fatal dementia

The influence of emotion regulation strategies and sleep quality on depression and anxiety

Chronic stress is a major risk factor for a number of mental health disorders, including depression and pathological anxiety. Adaptive cognitive emotion regulation (CER) strategies (i.e. positively-focused thought processes) can help to prevent psychiatric disturbance when enduring unpleasant and stressful experiences, but little is known about the inter-individual factors that govern their success. Sleep plays an important… Continue reading The influence of emotion regulation strategies and sleep quality on depression and anxiety

Hearing intervention versus health education control to reduce cognitive decline in older adults with hearing loss in the USA (ACHIEVE): a multicentre, randomised controlled trial

Hearing loss is associated with increased cognitive decline and incident dementia in older adults. We aimed to investigate whether a hearing intervention could reduce cognitive decline in cognitively healthy older adults with hearing loss.MethodsThe ACHIEVE study is a multicentre, parallel-group, unmasked, randomised controlled trial of adults aged 70–84 years with untreated hearing loss and without… Continue reading Hearing intervention versus health education control to reduce cognitive decline in older adults with hearing loss in the USA (ACHIEVE): a multicentre, randomised controlled trial

Vitamin D status & associations with inflammation in older adults

Research studies have observed associations of vitamin D with inflammation but data in representative older adult studies is lacking. We aimed to investigate the association of C-reactive protein (CRP) with vitamin D status in a representative sample of the older Irish population. The concentrations of 25-hydroxyvitamin D (25(OH)D) and CRP was measured in 5,381 community… Continue reading Vitamin D status & associations with inflammation in older adults

Physical Activity Dose and Depression in a Cohort of Older Adults in The Irish Longitudinal Study on Ageing

Importance  Among older adults (aged ≥50 years), depression is associated with an increased risk of physical, social, and cognitive dysfunction. Regular moderate to vigorous physical activity (MVPA) has been associated with lower odds of depression. However, the lowest dose for protection against depression and the extent to which exceeding this level conveys additional protection are unknown.Objective  To… Continue reading Physical Activity Dose and Depression in a Cohort of Older Adults in The Irish Longitudinal Study on Ageing

Objectively Measured Visual Impairment and Dementia Prevalence in Older Adults in the US

Importance  Estimates of the association between visual impairment (VI) and dementia in the US population are based on self-reported survey data or measures of visual function that are at least 15 years old. Older adults are at high risk of VI and dementia so there is a need for up-to-date national estimates based on objective assessments.Objective  To… Continue reading Objectively Measured Visual Impairment and Dementia Prevalence in Older Adults in the US

Cognitive Activity and Onset Age of Incident Alzheimer Disease Dementia

Objective To test the hypothesis that higher level of cognitive activity predicts older age at dementia onset in Alzheimer disease (AD) dementia.Methods As part of a longitudinal cohort study, 1,903 older persons without dementia at enrollment reported their frequency of participation in cognitively stimulating activities. They had annual clinical evaluations to diagnose dementia and AD, and the… Continue reading Cognitive Activity and Onset Age of Incident Alzheimer Disease Dementia

The associations of glycosylated hemoglobin with grey matter volume and depression: Investigating mediating role of grey matter volume

Highlights•This is the first study to investigate the mediation effect of GMV on the association between HbA1c and depression.•Hba1c was negatively associated with GMV, and that association were stronger in prediabetic participants.•Cerebral GMV plays a mediating role on the association “HbA1c-depression”, with a proportions of 6.82%.•Effective control of glycemia can potentially prevent brain abnormality and… Continue reading The associations of glycosylated hemoglobin with grey matter volume and depression: Investigating mediating role of grey matter volume

Association of Preoperative High-Intensity Interval Training With Cardiorespiratory Fitness and Postoperative Outcomes Among Adults Undergoing Major SurgeryA Systematic Review and Meta-Analysis

Importance  Preoperative high-intensity interval training (HIIT) is associated with improved cardiorespiratory fitness (CRF) and may improve surgical outcomes.Objective  To summarize data from studies comparing the association of preoperative HIIT vs standard hospital care with preoperative CRF and postoperative outcomes.Data Sources  Data sources included Medline, Embase, Cochrane Central Register of Controlled Trials Library, and Scopus databases with no language… Continue reading Association of Preoperative High-Intensity Interval Training With Cardiorespiratory Fitness and Postoperative Outcomes Among Adults Undergoing Major SurgeryA Systematic Review and Meta-Analysis