Efficacy of low-dose oral minoxidil in the management of anticancer therapy-induced alopecia in patients with breast cancer: A retrospective cohort study

To the Editor: Alopecia is feared by most patients undergoing systemic anticancer therapy for breast cancer because of its negative impact on quality of life.1 Currently, evidence regarding management of persistent chemotherapy-induced alopecia ( pCIA) and endocrine therapy-induced alopecia (EIA) in patients with breast cancer is lacking.2-4 Although previous studies demonstrated successful use of lowdose …

Continue reading Efficacy of low-dose oral minoxidil in the management of anticancer therapy-induced alopecia in patients with breast cancer: A retrospective cohort study

Evaluation of the Safety and Effectiveness of Nutritional Supplements for Treating Hair LossA Systematic Review

Importance  Despite the widespread use of nutritional supplements and dietary interventions for treating hair loss, the safety and effectiveness of available products remain unclear.Objective  To evaluate and compile the findings of all dietary and nutritional interventions for treatment of hair loss among individuals without a known baseline nutritional deficiency.Evidence Review  The MEDLINE, Embase, and CINAHL databases were searched …

Continue reading Evaluation of the Safety and Effectiveness of Nutritional Supplements for Treating Hair LossA Systematic Review

Evaluation of the Safety and Effectiveness of Nutritional Supplements for Treating Hair LossA Systematic Review

Importance  Despite the widespread use of nutritional supplements and dietary interventions for treating hair loss, the safety and effectiveness of available products remain unclear.Objective  To evaluate and compile the findings of all dietary and nutritional interventions for treatment of hair loss among individuals without a known baseline nutritional deficiency.Evidence Review  The MEDLINE, Embase, and CINAHL databases were searched …

Continue reading Evaluation of the Safety and Effectiveness of Nutritional Supplements for Treating Hair LossA Systematic Review

Alopecia areata following COVID-19 vaccination: vaccine-induced autoimmunity?

Dear Editor, We report a case of an 80-year-old man who came to our attention for a rapidly progressive loss of facial hair 7 days after the administration of the first dose of the BNT162b2 vaccine, an mRNA vaccine against SARS-CoV-2. He had no personal or family history of alopecia or autoimmunity. Before the vaccination, a …

Continue reading Alopecia areata following COVID-19 vaccination: vaccine-induced autoimmunity?

Two Phase 3 Trials of Baricitinib for Alopecia Areata

BACKGROUNDAlopecia areata is an autoimmune condition characterized by rapid hair loss in the scalp, eyebrows, and eyelashes, for which treatments are limited. Baricitinib, an oral, selective, reversible inhibitor of Janus kinases 1 and 2, may interrupt cytokine signaling implicated in the pathogenesis of alopecia areata. METHODSWe conducted two randomized, placebo-controlled, phase 3 trials (BRAVE-AA1 and …

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