The accumulation of age-associated cognitive deficits can lead to Mild Cognitive Impairment (MCI) and dementia. This is a major public health issue for the modern ageing population, as it impairs health, independence and overall quality of life. Keeping the brain active during life has been associated with an increased cognitive reserve, therefore reducing the risk… Continue reading The relationship between playing #musical instruments and #cognitive trajectories: Analysis from a UK ageing cohort
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ACG Clinical Guideline: #Alcohol-Associated #Liver Disease
Alcohol-associated liver disease (ALD) is the most common cause of advanced hepatic disease and frequent indication for liver transplantation worldwide. With harmful alcohol use as the primary risk factor, increasing alcohol use over the past decade has resulted in rapid growth of the ALD-related healthcare burden. The spectrum of ALD ranges from early asymptomatic liver… Continue reading ACG Clinical Guideline: #Alcohol-Associated #Liver Disease
#Autopsy findings in cases of fatal #COVID-19 #vaccine -induced #myocarditis
COVID-19 vaccines have been linked to myocarditis, which, in some circumstances, can be fatal. This systematic review aims to investigate potential causal links between COVID-19 vaccines and death from myocarditis using post-mortem analysis. We performed a systematic review of all published autopsy reports involving COVID-19 vaccination-induced myocarditis through 3 July 2023. All autopsy studies that… Continue reading #Autopsy findings in cases of fatal #COVID-19 #vaccine -induced #myocarditis
Hypo- and hyper- #thyroidism: algorithm for screening and diagnosis
Screening, diagnosing, and managing hypothyroidism: ATA/AACE guidelines recommend screening for all patients with symptoms of hypothyroidism. For patients whoare asymptomatic, recommendations vary widely. However, a thyroid-stimulating hormone (TSH) test is generallyrecommended for patients ≥50–60 years old, especially women. Guidelines also state that there is compelling evidence to support screening in patients with: Hypothyroidism: algorithm for… Continue reading Hypo- and hyper- #thyroidism: algorithm for screening and diagnosis
Association Between Electronic Diary–Rated #Sleep, Mood, Energy, and #Stress With Incident #Headache in a Community-Based Sample
The aim of this study was to examine the diurnal links between average and changes in average levels of prospectively rated mood, sleep, energy, and stress as predictors of incident headache in a community-based sample.MethodsThis observational study included structured clinical diagnostic assessment of both headache syndromes and mental disorders and electronic diaries that were administered… Continue reading Association Between Electronic Diary–Rated #Sleep, Mood, Energy, and #Stress With Incident #Headache in a Community-Based Sample
Do interventions for mood improve #inflammatory biomarkers in inflammatory #bowel disease?: A systematic review and meta-analysis
BackgroundPsychoneuroimmunological mechanisms and the gut-brain axis appear relevant to disease activity and progression in Inflammatory Bowel Disease (IBD). A recent review showed no effect of psychological therapies on self-reported disease activity in IBD. This meta-analysis aims to establish whether interventions targeting mood outcomes (e.g., depression, anxiety and stress) impact inflammation levels in IBD and possible… Continue reading Do interventions for mood improve #inflammatory biomarkers in inflammatory #bowel disease?: A systematic review and meta-analysis
#Statins and risks of #dementia among patients with heart failure: a population-based retrospective cohort study in Hong Kong
Heart failure (HF) and dementia frequently co-exist with shared pathological mechanisms and risk factors. Our study aims to investigate the association between statin therapy and the risks of dementia and its subtypes among patients with HF.MethodsThe Hong Kong Clinical Data Analysis and Reporting System database was interrogated to identify patients with incident HF diagnosis from… Continue reading #Statins and risks of #dementia among patients with heart failure: a population-based retrospective cohort study in Hong Kong
#Migraine is associated with the development of adult patients with inflammatory #bowel disease: a nationwide, population-based study
It has been reported that migraine is more common in patients with inflammatory bowel disease (IBD) than in general. However, the impact of migraine on the development of IBD has not yet been elucidated. The aim of this study was to determine the association between migraine and the development of IBD. This nationwide population-based cohort… Continue reading #Migraine is associated with the development of adult patients with inflammatory #bowel disease: a nationwide, population-based study
Self-Reported Frequency of Adding #Salt to Food and Risk of Incident Chronic #Kidney Disease
Importance The self-reported frequency of adding salt to foods could reflect a person’s long-term salt taste preference, and salt intake has been associated with increased risk of cardiovascular diseases (CVD). Whether self-reported adding of salt to foods is associated with increased risk of chronic kidney disease (CKD) remains unknown.Objective To prospectively examine the association of self-reported frequency… Continue reading Self-Reported Frequency of Adding #Salt to Food and Risk of Incident Chronic #Kidney Disease
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