..The present study aimed to assess the value of coronary artery calcium (CAC) for guiding aspirin allocation for primary prevention using 2019 aspirin meta-analysis data on CVD relative risk reduction (RRR) and bleeding risk ..Only 5% of MESA participants would qualify for aspirin consideration for primary prevention according to ACC/AHA guidelines and using >20% estimated… Continue reading #Coronary Artery Calcium for Personalized Allocation of #Aspirin in Primary Prevention of Cardiovascular Disease in 2019: The Multi-Ethnic Study of Atherosclerosis (MESA)
Author: aledopress
Medicine and Technology enthusiast..
CDC Hepatitis C screening among adults
..CDC is augmenting previous guidance with two new recommendations: 1) hepatitis C screening at least once in a lifetime for all adults aged ≥18 years, except in settings where the prevalence of HCV infection is <0.1% and 2) hepatitis C screening for all pregnant women during each pregnancy, except in settings where the prevalence of… Continue reading CDC Hepatitis C screening among adults
Association of intermittent and constant #knee pain patterns with knee pain severity, radiographic knee #osteoarthritis duration and severity
..Intermittent and Constant OA Pain (ICOAP) scores were characterized as 1) no intermittent or constant pain; 2) intermittent pain only; 3) constant pain only; and 4) a combination of constant and intermittent pain. Knee pain severity was assessed using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain subscale and the Visual Analog Scale… Continue reading Association of intermittent and constant #knee pain patterns with knee pain severity, radiographic knee #osteoarthritis duration and severity
Effectiveness of Surgical and Cotton #Masks in Blocking SARS–CoV-2: A Controlled Comparison in 4 Patients
..Neither surgical nor cotton masks effectively filtered SARS–CoV-2 during coughs by infected patients. Prior evidence that surgical masks effectively filtered influenza virus (1) informed recommendations that patients with confirmed or suspected COVID-19 should wear face masks to prevent transmission (2). However, the size and concentrations of SARS–CoV-2 in aerosols generated during coughing are unknown. Oberg… Continue reading Effectiveness of Surgical and Cotton #Masks in Blocking SARS–CoV-2: A Controlled Comparison in 4 Patients
Heat-inactivated #Bifidobacterium bifidum MIMBb75 (SYN-HI-001) in the treatment of #irritable bowel syndrome: a multicentre, randomised, double-blind, placebo-controlled clinical trial
Bifidobacterium bifidum MIMBb75 is one of a few probiotic strains that have been shown to be effective in the treatment of irritable bowel syndrome (IBS) and its symptoms. Non-viable strains might have advantages over viable bacteria for product stability and standardisation, as well as for tolerability because safety concerns have been raised for specific patient… Continue reading Heat-inactivated #Bifidobacterium bifidum MIMBb75 (SYN-HI-001) in the treatment of #irritable bowel syndrome: a multicentre, randomised, double-blind, placebo-controlled clinical trial
Association Between Lifetime Affective Symptoms and Premature Mortality
Associations between affective problems (anxiety and depression) and premature mortality have been demonstrated among psychiatric, medical, and community-based samples and across many causes of death.. ..Of 3001 study members (1509 [50.3%] female, 1492 [49.7%] male), 235 individuals (7.8%) died over a 15-year follow-up. After adjustment for sex, those who experienced case-level affective symptoms 1, 2,… Continue reading Association Between Lifetime Affective Symptoms and Premature Mortality
Association Between #Celiac Disease and Mortality Risk in a Swedish Population
There were 49 829 patients with celiac disease, including 24% who were diagnosed between the years 2010 and 2017. The mean (SD) age at diagnosis was 32.2 (25.2) years and 62.4% were women. During a median follow-up time of 12.5 years, 13.2% (n = 6596) died. Compared with controls (n = 246 426), overall mortality was increased in those with celiac… Continue reading Association Between #Celiac Disease and Mortality Risk in a Swedish Population
Cardiac #Autoimmunity Is Associated With Subclinical Myocardial Dysfunction in Patients With Type 1 #Diabetes Mellitus
The existence of a diabetic cardiomyopathy has been postulated to explain the increased risk of heart failure (HF) in patients with diabetes mellitus; however, whether mechanisms specific to type 1 diabetes mellitus (T1DM) affect the myocardium is unclear. We have recently shown that poor glycemic control in patients with T1DM followed in the DCCT (Diabetes… Continue reading Cardiac #Autoimmunity Is Associated With Subclinical Myocardial Dysfunction in Patients With Type 1 #Diabetes Mellitus
Early Transmission Dynamics in Wuhan, China, of Novel #Coronavirus–Infected Pneumonia
The initial cases of novel coronavirus (2019-nCoV)–infected pneumonia (NCIP) occurred in Wuhan, Hubei Province, China, in December 2019 and January 2020. We analyzed data on the first 425 confirmed cases in Wuhan to determine the epidemiologic characteristics of NCIP.. ..Among the first 425 patients with confirmed NCIP, the median age was 59 years and 56%… Continue reading Early Transmission Dynamics in Wuhan, China, of Novel #Coronavirus–Infected Pneumonia
