..Higher alcohol consumption (β=0.03, p<0.001), lower physical activity (β=0.002,p=001), smoking (β=1.58, p<0.001), men (p<0.001), African-Americans (p<0.001), impaired left ventricular relaxation (e´,β=-0.13, p=0.002), and worse diastolic function (E/e´,β=0.1, p=0.01) were associated with longitudinal increases in resting heart rate. We observed 268 cardiovascular disease and 74 heart failure events over a median of 26 years. In Cox… Continue reading Temporal Changes in Resting #Heart Rate, Left Ventricular Dysfunction, Heart #Failure and Cardiovascular Disease: CARDIA Study
Tag: CVD
Association of Isolated Diastolic #Hypertension as Defined by the 2017 ACC/AHA Blood Pressure Guideline With Incident Cardiovascular Outcomes
..the definition of hypertension was lowered from a blood pressure (BP) of greater than or equal to 140/90 to greater than or equal to 130/80 mm Hg. The new diastolic BP threshold of 80 mm Hg was recommended based on expert opinion and changes the definition of isolated diastolic hypertension (IDH). atherosclerotic cardiovascular disease (ASCVD)… Continue reading Association of Isolated Diastolic #Hypertension as Defined by the 2017 ACC/AHA Blood Pressure Guideline With Incident Cardiovascular Outcomes
Implications of Abnormal Exercise Electrocardiography With Normal Stress Echocardiography
..After excluding submaximal tests and nondiagnostic ECG or stress imaging results, 15 077 patients (mean [SD] age, 52 [13] years; 6228 [41.3%] men) were classified by stress test results Death occurred in 425 patients with −ECG/−Echo (4.8%), 50 patients with +ECG/−Echo (5.9%), and 70 patients with +Echo (11.2%). Myocardial infarction occurred in 195 patients with −ECG/−Echo… Continue reading Implications of Abnormal Exercise Electrocardiography With Normal Stress Echocardiography
Abdominal #obesity and the risk of recurrent atherosclerotic cardiovascular disease after myocardial #infarction
..Univariate and multivariable-adjusted Cox regression models were used to calculate hazard ratios and 95% confidence intervals in quintiles of waist circumference as well as three categories of body mass index including normal weight, overweight and obesity. Results The majority of patients had abdominal obesity. During a median follow-up time of 3.8 years, 1232 men (7.3%)… Continue reading Abdominal #obesity and the risk of recurrent atherosclerotic cardiovascular disease after myocardial #infarction
Sex Differences in Blood #Pressure Trajectories Over the Life Course
..Women compared with men exhibited a steeper increase in BP that began as early as in the third decade and continued through the life course (likelihood ratio test χ2 = 531 for systolic BP; χ2 = 123 for diastolic BP; χ2 = 325 for MAP; and χ2 = 572 for PP; P for all <.001). After adjustment for multiple cardiovascular disease risk factors,… Continue reading Sex Differences in Blood #Pressure Trajectories Over the Life Course
Intensive vs Standard Blood #Pressure Control in Adults 80 Years or Older: A Secondary Analysis of the #Systolic Blood Pressure Intervention Trial
Participants with hypertension but without diabetes (N = 1167) were randomized to an SBP target below 120 mm Hg (intensive treatment) vs a target below 140 mm Hg (standard treatment).. Intensive treatment led to significant reductions in cardiovascular events (hazard ratio [HR] = .66; 95% confidence interval [CI] = .49‐.90), mortality (HR = .67; 95% CI =… Continue reading Intensive vs Standard Blood #Pressure Control in Adults 80 Years or Older: A Secondary Analysis of the #Systolic Blood Pressure Intervention Trial
#Tea consumption and the risk of atherosclerotic #cardiovascular disease and all-cause mortality: The China-PAR project
..Compared with never or non-habitual tea drinkers, the hazard ratio and 95% confidence interval among habitual tea drinkers was 0.80 (0.75–0.87), 0.78 (0.69–0.88), and 0.85 (0.79–0.90) for atherosclerotic cardiovascular disease incidence, atherosclerotic cardiovascular disease mortality, and all-cause mortality, respectively. Habitual tea drinkers had 1.41 years longer of atherosclerotic cardiovascular disease-free years and 1.26 years longer… Continue reading #Tea consumption and the risk of atherosclerotic #cardiovascular disease and all-cause mortality: The China-PAR project
Healthy #lifestyle and life #expectancy free of cancer, cardiovascular disease, and type 2 diabetes: prospective cohort study
..Five low risk lifestyle factors: never smoking, body mass index 18.5-24.9, moderate to vigorous physical activity (≥30 minutes/day), moderate alcohol intake (women: 5-15 g/day; men 5-30 g/day), and a higher diet quality score (upper 40%). .. The life expectancy free of diabetes, cardiovascular diseases, and cancer at age 50 was 23.7 years (95% confidence interval… Continue reading Healthy #lifestyle and life #expectancy free of cancer, cardiovascular disease, and type 2 diabetes: prospective cohort study
Relation of Total #Sugars, Sucrose, Fructose, and Added Sugars With the Risk of #Cardiovascular Disease
..Total sugars, sucrose, and fructose were not associated with CVD incidence. Total sugars (risk ratio, 1.09 [95% confidence interval, 1.02 to 1.17]) and fructose (1.08 [1.01 to 1.15]) showed a harmful association for CVD mortality, there was no association for added sugars and a beneficial association for sucrose (0.94 [0.89 to 0.99]). Dose-response analyses showed… Continue reading Relation of Total #Sugars, Sucrose, Fructose, and Added Sugars With the Risk of #Cardiovascular Disease
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