Blood pressure (BP) management in frail older people is challenging. An randomised controlled trial of largely non-frail older people found cardiovascular and mortality benefit with systolic (S) BP target <120 mmHg. However, all-cause mortality by attained BP in routine care in frail adults aged above 75 is unclear.. ..Risks of cardiovascular outcomes increased with SBPs… Continue reading Blood #pressure in frail older adults: associations with #cardiovascular outcomes and all-cause mortality
Tag: CVD
Olive Oil Consumption and Cardiovascular Risk in U.S. Adults
Olive oil intake has been associated with lower risk of cardiovascular disease (CVD) in Mediterranean populations, but little is known about these associations in the U.S population. ..During 24 years of follow-up, we documented 9,797 incident cases of CVD, including 6,034 CHD cases and 3,802 stroke cases. After adjusting for major diet and lifestyle factors,… Continue reading Olive Oil Consumption and Cardiovascular Risk in U.S. Adults
#Beverage Consumption and Longitudinal Changes in Lipoprotein Concentrations and Incident #Dyslipidemia in US Adults: The Framingham Heart Study
Limited data are available on the prospective relationship between beverage consumption and plasma lipid and lipoprotein concentrations. Two major sources of sugar in the US diet are sugar‐sweetened beverages (SSBs) and 100% fruit juices. Low‐calorie sweetened beverages are common replacements.. ..We found that regular (>1 serving per day) versus low (<1 serving per month) SSB… Continue reading #Beverage Consumption and Longitudinal Changes in Lipoprotein Concentrations and Incident #Dyslipidemia in US Adults: The Framingham Heart Study
Total #Sitting Time and Sitting Pattern in Postmenopausal Women Differ by Hispanic Ethnicity and are Associated With #Cardiometabolic Risk Biomarkers
Sedentary behavior is pervasive, especially in older adults, and is associated with cardiometabolic disease and mortality. Relationships between cardiometabolic biomarkers and sitting time are unexplored in older women, as are possible ethnic differences.. ..Hispanic women sat, on average, 50.3 minutes less/day than non‐Hispanic women (P<0.001) and had shorter (3.6 minutes less, P=0.02) mean sitting bout… Continue reading Total #Sitting Time and Sitting Pattern in Postmenopausal Women Differ by Hispanic Ethnicity and are Associated With #Cardiometabolic Risk Biomarkers
Clinical Implications of the New York Heart Association Classification
The New York Heart Association (NYHA) classification has served as a fundamental tool for risk stratification of heart failure (HF) and determines clinical trial eligibility and candidacy for drugs and devices. However, its ability to adequately stratify risk is unclear.. Cumulative mortality varied significantly across NYHA classes and HF clinical trials (likelihood ratio, P<0.001). Mortality… Continue reading Clinical Implications of the New York Heart Association Classification
The intestinal #microbiota and #cardiovascular disease
The intestinal microbiota of human hosts is the community of microorganisms living in the small and, mainly, the large intestine of humans. This microbial ecosystem has co-evolved with humans across the millennia, has come to play an important interactive role in human physiology and has been aptly called our forgotten organ. Significant properties of the… Continue reading The intestinal #microbiota and #cardiovascular disease
Red #blood cell dysfunction: a new player in #cardiovascular disease
The primary role of red blood cells (RBCs) is to transport oxygen to the tissues and carbon dioxide to the lungs. However, emerging evidence suggests an important role of the RBC beyond being just a passive carrier of the respiratory gases. The RBCs are of importance for redox balance and are actively involved in the… Continue reading Red #blood cell dysfunction: a new player in #cardiovascular disease
The associations of major #foods and fibre with risks of ischaemic and haemorrhagic #stroke: a prospective study of 418 329 participants in the EPIC cohort across nine European countries
..For ischaemic stroke (4281 cases), lower risks were observed with higher consumption of fruit and vegetables combined (HR; 95% CI per 200 g/day higher intake, 0.87; 0.82–0.93, P-trend < 0.001), dietary fibre (per 10 g/day, 0.77; 0.69–0.86, P-trend < 0.001), milk (per 200 g/day, 0.95; 0.91–0.99, P-trend = 0.02), yogurt (per 100 g/day, 0.91; 0.85–0.97, P-trend = 0.004), and cheese (per 30 g/day, 0.88; 0.81–0.97, P-trend = 0.008), while higher… Continue reading The associations of major #foods and fibre with risks of ischaemic and haemorrhagic #stroke: a prospective study of 418 329 participants in the EPIC cohort across nine European countries
Age at #period cessation and trajectories of #cardiovascular risk factors across mid and later life
To examine the association between age at period cessation and trajectories of anthropometry, blood pressure, lipids and glycated haemoglobin (HbA1c) from midlife to age 69 years.. ..We found no evidence that age at period cessation was associated with trajectories of log triglyceride, LDL-C and HDL-C from 53 to 69 years and trajectories of SBP or… Continue reading Age at #period cessation and trajectories of #cardiovascular risk factors across mid and later life
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