Excessive coffee consumption can lead to unpleasant sensations such as tachycardia and heart palpitations. ObjectivesOur aim was to investigate if cardiovascular symptoms can lead to alterations in habitual patterns of coffee consumption. MethodsWe used information from up to 390,435 European ancestry participants in the UK Biobank, aged 39–73 y. Habitual coffee consumption was self-reported, and… Continue reading #Cardiovascular symptoms affect the patterns of habitual #coffee consumption
Tag: CVD
Genetic analysis in European ancestry individuals identifies 517 loci associated with #liver enzymes
Serum concentration of hepatic enzymes are linked to liver dysfunction, metabolic and cardiovascular diseases. We perform genetic analysis on serum levels of alanine transaminase (ALT), alkaline phosphatase (ALP) and gamma-glutamyl transferase (GGT) using data on 437,438 UK Biobank participants. Replication in 315,572 individuals from European descent from the Million Veteran Program, Rotterdam Study and Lifeline… Continue reading Genetic analysis in European ancestry individuals identifies 517 loci associated with #liver enzymes
Pharmacological blood #pressure lowering for primary and secondary prevention of cardiovascular disease across different levels of blood pressure: an individual participant-level data meta-analysis
The effects of pharmacological blood pressure lowering at normal or high-normal blood pressure ranges in people with or without pre-existing cardiovascular disease remains uncertain. We analysed individual participant data from randomised trials to investigate the effects of blood pressure lowering treatment on the risk of major cardiovascular events by baseline levels of systolic blood pressure.… Continue reading Pharmacological blood #pressure lowering for primary and secondary prevention of cardiovascular disease across different levels of blood pressure: an individual participant-level data meta-analysis
Long-term body mass index changes in #overweight and #obese adults and the risk of heart failure, #cardiovascular disease and mortality: a cohort study of over 260,000 adults in the UK
Although obesity is a well-recognised risk factor for cardiovascular disease (CVD), the impact of long-term body mass index (BMI) changes in overweight or obese adults, on the risk of heart failure, CVD and mortality has not been quantified. MethodsThis population-based cohort study used routine UK primary care electronic health data linked to secondary care and… Continue reading Long-term body mass index changes in #overweight and #obese adults and the risk of heart failure, #cardiovascular disease and mortality: a cohort study of over 260,000 adults in the UK
Exploring Posttraumatic #Stress Disorder as a #Cardiovascular Risk Factor in Women VeteransThe Heart of the Matter
The connection between emotional and physical health has long been recognized, with a great deal of research focusing on the risk of cardiovascular disease (CVD). The landmark INTERHEART study1 of nearly 30 000 people from 52 countries found that psychosocial factors, including depression and stressful life events, accounted for approximately one-third of the population-attributable risk of… Continue reading Exploring Posttraumatic #Stress Disorder as a #Cardiovascular Risk Factor in Women VeteransThe Heart of the Matter
Association of spontaneous #abortion with all cause and cause specific premature #mortality: prospective cohort study
To investigate the association of spontaneous abortion with the risk of all cause and cause specific premature mortality (death before the age of 70). Design Prospective cohort study. Setting The Nurses’ Health Study II (1993-2017), United States. Participants 101 681 ever gravid female nurses participating in the Nurses’ Health Study II. Main outcomes measures Lifetime occurrence… Continue reading Association of spontaneous #abortion with all cause and cause specific premature #mortality: prospective cohort study
Sex Differences in the Association of Body Composition and #Cardiovascular Mortality
To determine whether differences in body composition contribute to sex differences in cardiovascular disease (CVD) mortality, we investigated the relationship between components of body composition and CVD mortality in healthy men and women. Methods and Results Dual energy x‐ray absorptiometry body composition data from the National Health and Nutrition Examination Survey 1999–2004 and CVD mortality… Continue reading Sex Differences in the Association of Body Composition and #Cardiovascular Mortality
Risk for recurrent #cardiovascular disease events among patients with #diabetes and chronic kidney disease
Adults who have experienced multiple cardiovascular disease (CVD) events have a very high risk for additional events. Diabetes and chronic kidney disease (CKD) are each associated with an increased risk for recurrent CVD events following a myocardial infarction (MI). Methods We compared the risk for recurrent CVD events among US adults with health insurance who… Continue reading Risk for recurrent #cardiovascular disease events among patients with #diabetes and chronic kidney disease
Risk of #Cardiovascular Disease Mortality in Relation to #Depression and 14 Common Risk Factors
Depression has been linked to a worse prognosis of Cardiovascular disease (CVD), and these two diseases share a variety of common risk factors such as unhealthy lifestyles and chronic medical conditions. However, the potential role of these common risk factors in modulating the association between depression and CVD mortality and whether the co-occurrence of depression… Continue reading Risk of #Cardiovascular Disease Mortality in Relation to #Depression and 14 Common Risk Factors