Question Is the gut microbiota associated with cognitive function? Findings In this cross-sectional study, β-diversity, a measure of gut microbial community composition, was statistically significantly associated with all measures of cognitive function. Several specific genera were also significantly associated with 1 or more measures of cognitive function after adjustment for multiple comparisons. Meaning These results… Continue reading Association of the Gut Microbiota With Cognitive Function in Midlife
Tag: Cognitive
Evaluation of Adiposity and Cognitive Function in Adults
Excess adipose tissue increases other cardiovascular risk factors, which may be associated with vascular brain injury and cognitive impairment. However, the extent to which the amount and distribution of adipose tissue may be associated with lower cognitive scores, independent of its association with cardiovascular risk factors, is not well characterized. Objective To investigate the association… Continue reading Evaluation of Adiposity and Cognitive Function in Adults
Air quality improvement and cognitive decline in community-dwelling older women in the United States: A longitudinal cohort study
Late-life exposure to ambient air pollution is a modifiable risk factor for dementia, but epidemiological studies have shown inconsistent evidence for cognitive decline. Air quality (AQ) improvement has been associated with improved cardiopulmonary health and decreased mortality, but to the best of our knowledge, no studies have examined the association with cognitive function. We examined… Continue reading Air quality improvement and cognitive decline in community-dwelling older women in the United States: A longitudinal cohort study
Neurophysiological and Brain Structural Markers of Cognitive Frailty Differ from Alzheimer’s Disease
With increasing life span and prevalence of dementia, it is important to understand the mechanisms of cognitive aging. Here, we focus on a subgroup of the population we term “cognitively frail,” defined by reduced cognitive function in the absence of subjective memory complaints, or a clinical diagnosis of dementia. Cognitive frailty is distinct from cognitive… Continue reading Neurophysiological and Brain Structural Markers of Cognitive Frailty Differ from Alzheimer’s Disease
Probiotics for Mild Cognitive Impairment and Alzheimer’s Disease: A Systematic Review and Meta-Analysis
Accumulating evidence from animal studies supports the potential role of probiotics and prebiotics in alleviating neurodegenerative diseases. However, whether dietary supplementation with probiotics improves cognitive function in patients with Alzheimer’s disease (AD) or mild cognitive impairment (MCI) is unclear. We searched literature databases for relevant randomized control trials and compared the outcomes between control/placebo and… Continue reading Probiotics for Mild Cognitive Impairment and Alzheimer’s Disease: A Systematic Review and Meta-Analysis
Women who #breastfeed exhibit #cognitive benefits after age 50
AbstractBackground and objectivesWomen who breastfeed may experience long-term benefits for their health in addition to the more widely-appreciated effects on the breastfed child. Breastfeeding may induce long-term effects on biopsychosocial systems implicated in brain health. Also, due to diminished breastfeeding in the post-industrial era, it is important to understand the lifespan implications of breastfeeding for… Continue reading Women who #breastfeed exhibit #cognitive benefits after age 50
#Screen time and early adolescent #mental health, academic, and social outcomes in 9- and 10- year old children: Utilizing the Adolescent Brain #Cognitive Development ℠ (ABCD) Study
In a technology-driven society, screens are being used more than ever. The high rate of electronic media use among children and adolescents begs the question: is screen time harming our youth? The current study draws from a nationwide sample of 11,875 participants in the United States, aged 9 to 10 years, from the Adolescent Brain… Continue reading #Screen time and early adolescent #mental health, academic, and social outcomes in 9- and 10- year old children: Utilizing the Adolescent Brain #Cognitive Development ℠ (ABCD) Study
#Cognitive stimulation in the workplace, plasma proteins, and risk of #dementia: three analyses of population cohort studies
To examine the association between cognitively stimulating work and subsequent risk of dementia and to identify protein pathways for this association. Design Multicohort study with three sets of analyses. Setting United Kingdom, Europe, and the United States. Participants Three associations were examined: cognitive stimulation and dementia risk in 107 896 participants from seven population based prospective… Continue reading #Cognitive stimulation in the workplace, plasma proteins, and risk of #dementia: three analyses of population cohort studies
#Erythrocyte adenosine A2B receptor prevents #cognitive and #auditory dysfunction by promoting hypoxic and metabolic reprogramming
Hypoxia drives aging and promotes age-related cognition and hearing functional decline. Despite the role of erythrocytes in oxygen (O2) transport, their role in the onset of aging and age-related cognitive decline and hearing loss (HL) remains undetermined. Recent studies revealed that signaling through the erythrocyte adenosine A2B receptor (ADORA2B) promotes O2 release to counteract hypoxia… Continue reading #Erythrocyte adenosine A2B receptor prevents #cognitive and #auditory dysfunction by promoting hypoxic and metabolic reprogramming
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