Dietary #Carbohydrate Intake, Carbohydrate Quality, and Healthy #Aging in Women

Importance  Dietary carbohydrate quality is inversely associated with risks of chronic disease and all-cause mortality. However, limited evidence exists regarding the role of carbohydrate quality and dietary carbohydrate types in promoting healthy aging.Objective  To evaluate the long-term role of dietary carbohydrate intake and carbohydrate quality in healthy aging.Design, Setting, and Participants  This prospective cohort study… Continue reading Dietary #Carbohydrate Intake, Carbohydrate Quality, and Healthy #Aging in Women

Dietary #Carbohydrate and #Fat Intakes and Risk of Mortality in the Japanese Population: the Japan Multi-Institutional Collaborative Cohort Study

BackgroundPrevious cohort studies have yielded contradictory findings regarding the associations of dietary carbohydrate and fat intakes with risks of mortality.ObjectivesWe examined long-term associations of carbohydrate and fat intakes with mortality.MethodsIn this cohort study, 34,893 men and 46,440 women aged 35–69 y (mean body mass index of 23.7 and 22.2 kg/m2, respectively) were followed up from the baseline survey (2004–2014)… Continue reading Dietary #Carbohydrate and #Fat Intakes and Risk of Mortality in the Japanese Population: the Japan Multi-Institutional Collaborative Cohort Study

Dietary #Carbohydrate and #Fat Intakes and Risk of Mortality in the Japanese Population: the Japan Multi-Institutional Collaborative Cohort Study

BackgroundPrevious cohort studies have yielded contradictory findings regarding the associations of dietary carbohydrate and fat intakes with risks of mortality.ObjectivesWe examined long-term associations of carbohydrate and fat intakes with mortality.MethodsIn this cohort study, 34,893 men and 46,440 women aged 35–69 y (mean body mass index of 23.7 and 22.2 kg/m2, respectively) were followed up from the baseline survey (2004–2014)… Continue reading Dietary #Carbohydrate and #Fat Intakes and Risk of Mortality in the Japanese Population: the Japan Multi-Institutional Collaborative Cohort Study

Dietary #Carbohydrate and #Fat Intakes and Risk of #Mortality in the Japanese Population: the Japan Multi-Institutional Collaborative Cohort Study

BackgroundPrevious cohort studies have yielded contradictory findings regarding the associations of dietary carbohydrate and fat intakes with risks of mortality.ObjectivesWe examined long-term associations of carbohydrate and fat intakes with mortality.MethodsIn this cohort study, 34,893 men and 46,440 women aged 35–69 y (mean body mass index of 23.7 and 22.2 kg/m2, respectively) were followed up from the baseline survey (2004–2014)… Continue reading Dietary #Carbohydrate and #Fat Intakes and Risk of #Mortality in the Japanese Population: the Japan Multi-Institutional Collaborative Cohort Study

The #carbohydrate-insulin model: a physiological perspective on the #obesity pandemic

According to a commonly held view, the obesity pandemic is caused by overconsumption of modern, highly palatable, energy-dense processed foods, exacerbated by a sedentary lifestyle. However, obesity rates remain at historic highs, despite a persistent focus on eating less and moving more, as guided by the energy balance model (EBM). This public health failure may… Continue reading The #carbohydrate-insulin model: a physiological perspective on the #obesity pandemic

The Tailgate Study: Differing #metabolic effects of a bout of excessive #eating and #drinking

Excess energy intake by spectators at a sporting event (i.e., a tailgate) might cause acute negative health effects. However, limited data exist regarding the effects of overeating and alcohol consumption on lipid metabolism and the potential to gain intrahepatic triacylglycerols (IHTG). We tested the hypothesis that overconsumption of food and alcohol would significantly increase both… Continue reading The Tailgate Study: Differing #metabolic effects of a bout of excessive #eating and #drinking

A randomized controlled trial of 130 g/day low-#carbohydrate diet in type 2 #diabetes with poor glycemic control

The usefulness of low-carbohydrate diet (LCD) for Japanese patients with type 2 diabetes mellitus (T2DM) has not been fully investigated. Therefore, we compared the effectiveness and safety of LCD with calorie restricted diet (CRD). This prospective, randomized, open-label, comparative study included 66 T2DM patients with HbA1c >7.5% even after receiving repeated education programs on CRD.… Continue reading A randomized controlled trial of 130 g/day low-#carbohydrate diet in type 2 #diabetes with poor glycemic control

Low #carbohydrate diet and all cause and cause-specific #mortality

Evidence is limited regarding the association between low-carbohydrate diet (LCD) score and mortality among Asians, a population that consumes a large amount of carbohydrates.. ..A U-shaped association was observed between LCD score and total mortality: the multivariable-adjusted hazard ratios (HRs) (95% CI) of total mortality for lowest through highest scores were 1.00, 0.95 (0.91, 1.01),… Continue reading Low #carbohydrate diet and all cause and cause-specific #mortality

Short-Term Consumption of #Sucralose with, but Not without, #Carbohydrate Impairs Neural and Metabolic Sensitivity to Sugar in Humans

There is a general consensus that overconsumption of sugar-sweetened beverages contributes to the prevalence of obesity and related comorbidities such as type 2 diabetes (T2D). Whether a similar relationship exists for no- or low-calorie “diet” drinks is a subject of intensive debate and controversy. Here, we demonstrate that consuming seven sucralose-sweetened beverages with, but not… Continue reading Short-Term Consumption of #Sucralose with, but Not without, #Carbohydrate Impairs Neural and Metabolic Sensitivity to Sugar in Humans