This study aims to determine the contributions of sun exposure and ultraviolet radiation (UVR) exposure to risk of paediatric-onset multiple sclerosis (MS). Methods: Children with MS and controls recruited from multiple centres in the USA were matched on sex and age. Multivariable conditional logistic regression was used to investigate the association of time spent outdoors… Continue reading Association Between Time Spent Outdoors and Risk of Multiple Sclerosis
Category: Environment
Global warming and neurological practice: systematic review
Climate change, including global warming, will cause poorer global health and rising numbers of environmental refugees. As neurological disorders account for a major share of morbidity and mortality worldwide, global warming is also destined to alter neurological practice; however, to what extent and by which mechanisms is unknown. We aimed to collect information about the… Continue reading Global warming and neurological practice: systematic review
Variation in common laboratory test results caused by ambient temperature
Highlights•Analysis of a dataset of nearly 5 million and over 200 million laboratory test results •Ambient temperature on the day an individual’s blood was drawn affected the test result •Affected assays included renal function tests, complete blood count, and lipid panels •Doctors prescribed fewer statins to individuals whose lipids were checked on colder days. Context… Continue reading Variation in common laboratory test results caused by ambient temperature
Psychological and biological resilience modulates the effects of stress on epigenetic aging
Our society is experiencing more stress than ever before, leading to both negative psychiatric and physical outcomes. Chronic stress is linked to negative long-term health consequences, raising the possibility that stress is related to accelerated aging. In this study, we examine whether resilience factors affect stress-associated biological age acceleration. Recently developed “epigenetic clocks” such as… Continue reading Psychological and biological resilience modulates the effects of stress on epigenetic aging
Face masks: benefits and risks during the COVID-19 crisis
The German government has made it mandatory to wear respiratory masks covering mouth and nose (MNC) as an effective strategy to fight SARS-CoV-2 infections. In many countries, this directive has been extended on shopping malls or public transportation. The aim of this paper is to critically analyze the statutory regulation to wear protective masks during… Continue reading Face masks: benefits and risks during the COVID-19 crisis
Air pollution and endocrine disruptors induce human microbiome imbalances: A systematic review of recent evidence and possible biological mechanisms
Highlights•Environmental pollution could affect diversity of resident microbiota. •Environmental pollution could affect abundance of resident microbiota. •Studies suggest air pollution increases the abundance of streptococcus. •Studies suggest air pollution increases the abundance of veillionellales. •Scarcity of studies precludes observing consistent trends for other microbiota. AbstractA rich body of literature indicates that environmental factors interact with… Continue reading Air pollution and endocrine disruptors induce human microbiome imbalances: A systematic review of recent evidence and possible biological mechanisms
Community transmission and viral load kinetics of the SARS-CoV-2 delta (B.1.617.2) variant in vaccinated and unvaccinated individuals in the UK: a prospective, longitudinal, cohort study
The SARS-CoV-2 delta (B.1.617.2) variant is highly transmissible and spreading globally, including in populations with high vaccination rates. We aimed to investigate transmission and viral load kinetics in vaccinated and unvaccinated individuals with mild delta variant infection in the community. MethodsBetween Sept 13, 2020, and Sept 15, 2021, 602 community contacts (identified via the UK… Continue reading Community transmission and viral load kinetics of the SARS-CoV-2 delta (B.1.617.2) variant in vaccinated and unvaccinated individuals in the UK: a prospective, longitudinal, cohort study
Transmission of SARS-CoV-2 Delta Variant Among Vaccinated Healthcare Workers, Vietnam
Background: Data on breakthrough SARS-CoV-2 Delta variant infections are limited. Methods: We studied breakthrough infections among healthcare workers of a major infectious diseases hospital in Vietnam. We collected demographics, vaccination history and results of PCR diagnosis alongside clinical data. We measured SARS-CoV-2 (neutralizing) antibodies at diagnosis, and at week 1, 2 and 3 after diagnosis.… Continue reading Transmission of SARS-CoV-2 Delta Variant Among Vaccinated Healthcare Workers, Vietnam
Experiences of Work-Family Conflict and #Mental Health Symptoms by Gender Among Physician Parents During the #COVID-19 Pandemic
The COVID-19 pandemic has placed increased strain on health care workers and disrupted childcare and schooling arrangements in unprecedented ways. As substantial gender inequalities existed in medicine before the pandemic, physician mothers may be at particular risk for adverse professional and psychological consequences. Objective To assess gender differences in work-family factors and mental health among… Continue reading Experiences of Work-Family Conflict and #Mental Health Symptoms by Gender Among Physician Parents During the #COVID-19 Pandemic
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