In this brief communication we are showing original research results with early estimates from Danish nationwide databases of vaccine effectiveness (VE) against the novel SARS-CoV-2 Omicron variant (B.1.1.529) up to five months after a primary vaccination series with the BNT162b2 or mRNA-1273 vaccines. Our study provides evidence of protection against infection with the Omicron variant… Continue reading Vaccine effectiveness against SARS-CoV-2 infection with the Omicron or Delta variants following a two-dose or booster BNT162b2 or mRNA-1273 vaccination series: A Danish cohort study
Category: Environment
SARS-CoV-2 Omicron VOC Transmission in Danish Households
The Omicron variant of concern (VOC) is a rapidly spreading variant of SARS-CoV-2 that is likely to overtake the previously dominant Delta VOC in many countries by the end of 2021. We estimated the transmission dynamics following the spread of Omicron VOC within Danish households during December 2021. We used data from Danish registers to… Continue reading SARS-CoV-2 Omicron VOC Transmission in Danish Households
Evaluating the number of unvaccinated people needed to exclude to prevent SARS-CoV-2 transmissions
Vaccine mandates and vaccine passports (VMVP) for SARS-CoV-2 are thought to be a path out of the pandemic by increasing vaccination through coercion and excluding unvaccinated people from different settings because they are viewed as being at significant risk of transmitting SARS-CoV-2. While variants and waning efficacy are relevant, SARS-CoV-2 vaccines reduce the risk of… Continue reading Evaluating the number of unvaccinated people needed to exclude to prevent SARS-CoV-2 transmissions
Identification of TCR repertoires in functionally competent cytotoxic T cells cross-reactive to SARS-CoV-2
SARS-CoV-2-specific CD8+ T cells are scarce but detectable in unexposed healthy donors (UHDs). It remains unclear whether pre-existing human coronavirus (HCoV)-specific CD8+ T cells are converted to functionally competent T cells cross-reactive to SARS-CoV-2. Here, we identified the HLA-A24-high binding, immunodominant epitopes in SARS-CoV-2 spike region that can be recognized by seasonal coronavirus-specific CD8+ T… Continue reading Identification of TCR repertoires in functionally competent cytotoxic T cells cross-reactive to SARS-CoV-2
Christmas 2021: Time Warp The end of the pandemic will not be televised
Dashboards of pandemic statistics have dominated screens and helped to track covid-19, but David Robertson and Peter Doshi explain why they might not be enough to define its end As the year 2021 started, the covid-19 pandemic seemed to be receding. Discussions and predictions about “opening up,” a return to “normal,” and achieving herd immunity… Continue reading Christmas 2021: Time Warp The end of the pandemic will not be televised
Depression, anxiety, and happiness in dog owners and potential dog owners during the COVID-19 pandemic in the United States
Major life events, such as the COVID-19 pandemic, affect psychological and physiological health. Social support, or the lack thereof, can modulate these effects. The context of the COVID-19 pandemic offered a unique opportunity to better understand how dogs may provide social support for their owners and buffer heightened symptoms of stress, anxiety and depression and… Continue reading Depression, anxiety, and happiness in dog owners and potential dog owners during the COVID-19 pandemic in the United States
Association Between Time Spent Outdoors and Risk of Multiple Sclerosis
This study aims to determine the contributions of sun exposure and ultraviolet radiation (UVR) exposure to risk of paediatric-onset multiple sclerosis (MS). Methods: Children with MS and controls recruited from multiple centres in the USA were matched on sex and age. Multivariable conditional logistic regression was used to investigate the association of time spent outdoors… Continue reading Association Between Time Spent Outdoors and Risk of Multiple Sclerosis
Global warming and neurological practice: systematic review
Climate change, including global warming, will cause poorer global health and rising numbers of environmental refugees. As neurological disorders account for a major share of morbidity and mortality worldwide, global warming is also destined to alter neurological practice; however, to what extent and by which mechanisms is unknown. We aimed to collect information about the… Continue reading Global warming and neurological practice: systematic review
Variation in common laboratory test results caused by ambient temperature
Highlights•Analysis of a dataset of nearly 5 million and over 200 million laboratory test results •Ambient temperature on the day an individual’s blood was drawn affected the test result •Affected assays included renal function tests, complete blood count, and lipid panels •Doctors prescribed fewer statins to individuals whose lipids were checked on colder days. Context… Continue reading Variation in common laboratory test results caused by ambient temperature
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