Background Remission of type 2 diabetes can occur as a result of weight loss and is characterised by liver fat and pancreas fat reduction and recovered insulin secretion. In this analysis, we aimed to investigate the mechanisms of weight loss- induced remission in people with prediabetes.MethodsIn this prespecified post-hoc analysis, weight loss-induced resolution of prediabetes… Continue reading Mechanisms of #weight loss-induced remission in people with #prediabetes: a post-hoc analysis of the randomised, controlled, multicentre Prediabetes Lifestyle Intervention Study (PLIS)
Category: Diet
Effects of chronic #caffeine on patterns of #brain blood flow and behavior throughout the sleep–wake cycle in freely behaving mice
Caffeine has significant effects on neurovascular activity and behavior throughout the sleep–wake cycle. We used a minimally invasive microchip/video system to continuously record effects of caffeine in the drinking water of freely behaving mice. Chronic caffeine shifted both rest and active phases by up to 2 h relative to the light–dark cycle in a dose-dependent fashion.… Continue reading Effects of chronic #caffeine on patterns of #brain blood flow and behavior throughout the sleep–wake cycle in freely behaving mice
Dietary #Carbohydrate and #Fat Intakes and Risk of Mortality in the Japanese Population: the Japan Multi-Institutional Collaborative Cohort Study
BackgroundPrevious cohort studies have yielded contradictory findings regarding the associations of dietary carbohydrate and fat intakes with risks of mortality.ObjectivesWe examined long-term associations of carbohydrate and fat intakes with mortality.MethodsIn this cohort study, 34,893 men and 46,440 women aged 35–69 y (mean body mass index of 23.7 and 22.2 kg/m2, respectively) were followed up from the baseline survey (2004–2014)… Continue reading Dietary #Carbohydrate and #Fat Intakes and Risk of Mortality in the Japanese Population: the Japan Multi-Institutional Collaborative Cohort Study
#Ginger intake suppresses neutrophil extracellular trap formation in #autoimmune mice and healthy humans
We previously reported that treatment of mice with 6-gingerol, the most abundant phytochemical in ginger root, leads to phosphodiesterase inhibition that counteracts neutrophil hyperactivity in models of antiphospholipid syndrome (APS) and lupus. Here, we explored the extent to which oral intake of a whole-ginger extract would similarly impact neutrophils in both autoimmune mice and healthy… Continue reading #Ginger intake suppresses neutrophil extracellular trap formation in #autoimmune mice and healthy humans
Dietary Patterns, Foods, and #Nutrients to Ameliorate Non-Alcoholic #Fatty Liver Disease: A Scoping Review
Background: Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease without pharmacological treatment yet. There is also a lack of specific dietary recommendations and strategies to treat the negative health impacts derived from NAFLD. Objective: This scoping review aimed to compile dietary patterns, foods, and nutrients to ameliorate NAFLD. Methods:… Continue reading Dietary Patterns, Foods, and #Nutrients to Ameliorate Non-Alcoholic #Fatty Liver Disease: A Scoping Review
#Almonds vs. #carbohydrate snacks in an energy-restricted diet: Weight and cardiometabolic outcomes from a randomized trial
ObjectiveThis study evaluated weight and cardiometabolic outcomes after a 3-month energy-restricted diet (−30%) containing almonds (almond-enriched diet [AED]) or containing carbohydrate-rich snacks (nut-free control diet [NFD]) (Phase 1), followed by 6 months of weight maintenance (Phase 2).MethodsParticipants (25–65 years old) with overweight or obesity (BMI 27.5–34.9 kg/m2) were randomly allocated to AED (n = 68) or NFD (n = 72).ResultsBoth groups lost weight… Continue reading #Almonds vs. #carbohydrate snacks in an energy-restricted diet: Weight and cardiometabolic outcomes from a randomized trial
Dietary #Carbohydrate and #Fat Intakes and Risk of Mortality in the Japanese Population: the Japan Multi-Institutional Collaborative Cohort Study
BackgroundPrevious cohort studies have yielded contradictory findings regarding the associations of dietary carbohydrate and fat intakes with risks of mortality.ObjectivesWe examined long-term associations of carbohydrate and fat intakes with mortality.MethodsIn this cohort study, 34,893 men and 46,440 women aged 35–69 y (mean body mass index of 23.7 and 22.2 kg/m2, respectively) were followed up from the baseline survey (2004–2014)… Continue reading Dietary #Carbohydrate and #Fat Intakes and Risk of Mortality in the Japanese Population: the Japan Multi-Institutional Collaborative Cohort Study
Dietary #Carbohydrate and #Fat Intakes and Risk of #Mortality in the Japanese Population: the Japan Multi-Institutional Collaborative Cohort Study
BackgroundPrevious cohort studies have yielded contradictory findings regarding the associations of dietary carbohydrate and fat intakes with risks of mortality.ObjectivesWe examined long-term associations of carbohydrate and fat intakes with mortality.MethodsIn this cohort study, 34,893 men and 46,440 women aged 35–69 y (mean body mass index of 23.7 and 22.2 kg/m2, respectively) were followed up from the baseline survey (2004–2014)… Continue reading Dietary #Carbohydrate and #Fat Intakes and Risk of #Mortality in the Japanese Population: the Japan Multi-Institutional Collaborative Cohort Study
High #ultra-processed food consumption is associated with elevated #psychological distress as an indicator of #depression in adults from the Melbourne Collaborative Cohort Study
Highlights•Participants with the highest intake of ultra-processed food had increased odds of elevated psychological distress•We found no evidence for an interaction of sex, age and body mass index with ultra-processed food intake•Further research is needed to better inform nutrition-related and public health strategies for mental health BackgroundFew studies have tested longitudinal associations between ultra-processed food… Continue reading High #ultra-processed food consumption is associated with elevated #psychological distress as an indicator of #depression in adults from the Melbourne Collaborative Cohort Study
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