A Comparison of Biomarker Rise in Type 1 and Type 2 Myocardial Infarction

..Type 1 myocardial infarction tended to be larger than type 2 myocardial infarction, with a significantly higher mean percentage rise for both cTnT and CK-MB as well as higher mean RULN (207 vs 86 for cTnT, P = 0.02; 9 vs 4 for CK-MB, P = 0.002). There was a trend toward a higher rise… Continue reading A Comparison of Biomarker Rise in Type 1 and Type 2 Myocardial Infarction

Association between #statin use and incidence or progression of #osteoarthritis: Meta-analysis of observational studies

..A total of 11 studies (679807 participants) were identified from the systematic literature search. No significant association between statin use and incidence (OR = 1.010; 95% CI: 0.968 to 1.055; P = 0.638) or progression (OR = 1.076; 95% CI: 0.824 to 1.405; P = 0.589) of OA was found in our meta-analysis. The meta-analysis… Continue reading Association between #statin use and incidence or progression of #osteoarthritis: Meta-analysis of observational studies

#Coronary artery disease prediction in women and men using chest pain characteristics and risk factors: an observational study in outpatient clinics

..Twenty-four women (5%) and 75 men (15%) were diagnosed with coronary artery disease by invasive coronary angiography or CT angiography during regular care follow-up. Elastic net regression was performed to assess which chest pain characteristics and risk factors were of diagnostic value. The overall model selected age, provocation by temperature or stress, relief at rest… Continue reading #Coronary artery disease prediction in women and men using chest pain characteristics and risk factors: an observational study in outpatient clinics

MEANINGFUL CHANGE IN SIX-MINUTE #WALK IN PEOPLE WITH PERIPHERAL #ARTERY DISEASE

Six-minute walk is a common outcome in clinical trials of people with lower extremity peripheral artery disease (PAD). However, meaningful change in six-minute walk distance is not well defined in people with PAD.. ..777 participants with PAD (mean age: 71.2 years (standard deviation (SD)=8.8) mean baseline six-minute walk: 350.1 meters (SD=118.1) completed 5,439 questions about… Continue reading MEANINGFUL CHANGE IN SIX-MINUTE #WALK IN PEOPLE WITH PERIPHERAL #ARTERY DISEASE

#ST-Segment Elevation in Patients with #Covid-19 — A Case Series

Myocardial injury with ST-segment elevation has been observed in patients with coronavirus disease 2019 (Covid-19). Here, we describe our experience in the initial month of the Covid-19 outbreak in New York City. Patients with confirmed Covid-19 who had ST-segment elevation on electrocardiography were included in the study from six New York hospitals. Patients with Covid-19… Continue reading #ST-Segment Elevation in Patients with #Covid-19 — A Case Series

Effect of Smartphone-Enabled #Health Monitoring Devices vs Regular Follow-up on Blood Pressure Control Among Patients After Myocardial #Infarction

..For patients randomized to regular care, 4 physical outpatient clinic visits were scheduled in the year following the initial event. In the intervention group, patients were given 4 smartphone-compatible devices (weight scale, BP monitor, rhythm monitor, and step counter). In addition, 2 in-person outpatient clinic visits were replaced by electronic visits ..In total, 200 patients… Continue reading Effect of Smartphone-Enabled #Health Monitoring Devices vs Regular Follow-up on Blood Pressure Control Among Patients After Myocardial #Infarction

Clinical Implications of SARS-Cov2 Interaction with Renin #Angiotensin System

SARS-CoV2 host cell infection is mediated by the binding to angiotensin-converting enzyme 2 (ACE2). Systemic dysregulation observed in SARS-CoV was previously postulated to be due to ACE2/Ang1-7/Mas axis downregulation, increased ACE2 activity was shown to mediate disease protection. Since angiotensin II receptor blockers (ARBs), ACE inhibitors, and mineralocorticoid receptor antagonists (MRAs) increase ACE2 receptor expression,… Continue reading Clinical Implications of SARS-Cov2 Interaction with Renin #Angiotensin System

Large #thigh circumference is associated with lower blood #pressure in overweight and obese individuals: a community-based study

..A small thigh circumference is associated with an increased risk of diabetes, cardiovascular diseases, and total mortality. The purpose of this study was to evaluate the association between thigh circumference and hypertension in the middle-aged and elderly population. ..Thigh circumference was negatively correlated with systolic blood pressure, diastolic blood pressure, fasting glucose, and total cholesterol.… Continue reading Large #thigh circumference is associated with lower blood #pressure in overweight and obese individuals: a community-based study

Short-Term Progression of Multiterritorial Subclinical #Atherosclerosis

..Imaging detected short-term (3-year) atherosclerosis progression in 41.5% of participants (26.4% by 2DVUS, 21.3% by 3DVUS, and 11.5% by CACS), particularly in peripheral territories examined by vascular ultrasound. New atherosclerosis onset accounted for approximately one-third of total progression, also more frequently by 2DVUS and 3DVUS (29.1% and 16.6%, respectively), than by CACS (2.9%). Participants with… Continue reading Short-Term Progression of Multiterritorial Subclinical #Atherosclerosis