The risk of cardiovascular disease is increased among persons with human immunodeficiency virus (HIV) infection, so data regarding primary prevention strategies in this population are needed.METHODSIn this phase 3 trial, we randomly assigned 7769 participants with HIV infection with a low-to-moderate risk of cardiovascular disease who were receiving antiretroviral therapy to receive daily pitavastatin calcium… Continue reading Pitavastatin to Prevent Cardiovascular Disease in HIV Infection
Category: Cardiology
#Ultra-processed #food consumption is associated with all-cause and #cardiovascular mortality in participants with type 2 #diabetes independent of diet quality: a prospective observational cohort study
BackgroundNutritional strategies for prevention and management of type 2 diabetes traditionally emphasize dietary patterns reflecting nutrient goals, but the health implications of ultra-processed food (UPF) for patients with type 2 diabetes remain unknown.ObjectiveTo evaluate the association of UPF intake with all-cause and cardiovascular disease (CVD) mortality amongst participants with type 2 diabetes from the Moli-sani… Continue reading #Ultra-processed #food consumption is associated with all-cause and #cardiovascular mortality in participants with type 2 #diabetes independent of diet quality: a prospective observational cohort study
Vegetarian Dietary Patterns and Cardiometabolic Risk in People With or at High Risk of Cardiovascular DiseaseA Systematic Review and Meta-analysis
MPORTANCE Plant-based diets are known to improve cardiometabolic risk in the general population, but their effects on people at high risk of cardiovascular diseases (CVDs) remain inconclusive.OBJECTIVE To assess the association of vegetarian diets with major cardiometabolic risk factors,including low-density lipoprotein cholesterol (LDL-C), hemoglobin A1c (HbA1c), systolic blood pressure (SBP), and body weight in people… Continue reading Vegetarian Dietary Patterns and Cardiometabolic Risk in People With or at High Risk of Cardiovascular DiseaseA Systematic Review and Meta-analysis
Accelerometer-Derived “Weekend Warrior” Physical Activity and Incident Cardiovascular Disease
Guidelines recommend 150 minutes or more of moderate to vigorous physical activity (MVPA) per week for overall health benefit, but the relative effects of concentrated vs more evenly distributed activity are unclear.Objective To examine associations between an accelerometer-derived “weekend warrior” pattern (ie, most MVPA achieved over 1-2 days) vs MVPA spread more evenly with risk of… Continue reading Accelerometer-Derived “Weekend Warrior” Physical Activity and Incident Cardiovascular Disease
Vitamin D supplementation and major cardiovascular events: D-Health randomised controlled trial
To investigate whether supplementing older adults with monthly doses of vitamin D alters the incidence of major cardiovascular events Design Randomised, double blind, placebo controlled trial of monthly vitamin D (the D-Health Trial). Computer generated permuted block randomisation was used to allocate treatments.Setting Australia from 2014 to 2020.Participants 21 315 participants aged 60-84 years at enrolment. Exclusion criteria were… Continue reading Vitamin D supplementation and major cardiovascular events: D-Health randomised controlled trial
Frailty and Outcomes Following Cardiopulmonary Resuscitation for Perioperative Cardiac Arrest
Frailty is associated with mortality following surgery and cardiopulmonary resuscitation (CPR) for in-hospital cardiac arrest. Despite the growing focus on frailty as a basis for preoperative risk stratification and concern that CPR in patients with frailty may border on futility, the association between frailty and outcomes following perioperative CPR is unknown.Objective To determine the association between… Continue reading Frailty and Outcomes Following Cardiopulmonary Resuscitation for Perioperative Cardiac Arrest
Increased emergency cardiovascular events among under-40 population in Israel during vaccine rollout and third COVID-19 wave
Cardiovascular adverse conditions are caused by coronavirus disease 2019 (COVID-19) infections and reported as side-effects of the COVID-19 vaccines. Enriching current vaccine safety surveillance systems with additional data sources may improve the understanding of COVID-19 vaccine safety. Using a unique dataset from Israel National Emergency Medical Services (EMS) from 2019 to 2021, the study aims… Continue reading Increased emergency cardiovascular events among under-40 population in Israel during vaccine rollout and third COVID-19 wave
Infused juice concentrate of Japanese plum Prunus mume attenuates inflammatory vascular remodeling in a mouse model of hypertension induced by angiotensin II
Fruit from the Prunus mume tree is a traditional food in Japan. Recently, bainiku-ekisu, an infused juice concentrate of Japanese Prunus mume, is attracting attention as a health promoting supplement. Angiotensin II (Ang II) plays a central role in development of hypertension. It has been reported that bainiku-ekisu treatment attenuates the growth-promoting signaling induced by Ang II in… Continue reading Infused juice concentrate of Japanese plum Prunus mume attenuates inflammatory vascular remodeling in a mouse model of hypertension induced by angiotensin II
Myocarditis Cases Reported After mRNA-Based COVID-19 Vaccination in the US From December 2020 to August 2021
Vaccination against COVID-19 provides clear public health benefits, but vaccination also carries potential risks. The risks and outcomes of myocarditis after COVID-19 vaccination are unclear.Objective To describe reports of myocarditis and the reporting rates after mRNA-based COVID-19 vaccination in the US.Design, Setting, and Participants Descriptive study of reports of myocarditis to the Vaccine Adverse Event Reporting System… Continue reading Myocarditis Cases Reported After mRNA-Based COVID-19 Vaccination in the US From December 2020 to August 2021
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