We previously reported that treatment of mice with 6-gingerol, the most abundant phytochemical in ginger root, leads to phosphodiesterase inhibition that counteracts neutrophil hyperactivity in models of antiphospholipid syndrome (APS) and lupus. Here, we explored the extent to which oral intake of a whole-ginger extract would similarly impact neutrophils in both autoimmune mice and healthy… Continue reading #Ginger intake suppresses neutrophil extracellular trap formation in #autoimmune mice and healthy humans
Author: aledopress
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Dietary Patterns, Foods, and #Nutrients to Ameliorate Non-Alcoholic #Fatty Liver Disease: A Scoping Review
Background: Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease without pharmacological treatment yet. There is also a lack of specific dietary recommendations and strategies to treat the negative health impacts derived from NAFLD. Objective: This scoping review aimed to compile dietary patterns, foods, and nutrients to ameliorate NAFLD. Methods:… Continue reading Dietary Patterns, Foods, and #Nutrients to Ameliorate Non-Alcoholic #Fatty Liver Disease: A Scoping Review
Inability to work following #COVID-19 vaccination-a relevant aspect for future booster vaccinations
Objectives: COVID-19 vaccination is a key prevention strategy to reduce the spread and severity of SARS-CoV-2 infections. However, vaccine-related inability to work among healthcare workers (HCWs) could overstrain healthcare systems.Study design: The study presented was conducted as part of the prospective CoVacSer cohort study.Methods: This study examined sick leave and intake of pro re nata medication after the… Continue reading Inability to work following #COVID-19 vaccination-a relevant aspect for future booster vaccinations
#Almonds vs. #carbohydrate snacks in an energy-restricted diet: Weight and cardiometabolic outcomes from a randomized trial
ObjectiveThis study evaluated weight and cardiometabolic outcomes after a 3-month energy-restricted diet (−30%) containing almonds (almond-enriched diet [AED]) or containing carbohydrate-rich snacks (nut-free control diet [NFD]) (Phase 1), followed by 6 months of weight maintenance (Phase 2).MethodsParticipants (25–65 years old) with overweight or obesity (BMI 27.5–34.9 kg/m2) were randomly allocated to AED (n = 68) or NFD (n = 72).ResultsBoth groups lost weight… Continue reading #Almonds vs. #carbohydrate snacks in an energy-restricted diet: Weight and cardiometabolic outcomes from a randomized trial
Psychosocial #Stressors at #Work and #Coronary Heart Disease Risk in Men and Women: 18-Year Prospective Cohort Study of Combined Exposures
Psychosocial stressors at work, like job strain and effort-reward imbalance (ERI), can increase coronary heart disease (CHD) risk. ERI indicates an imbalance between the effort and received rewards. Evidence about the adverse effect of combined exposure to these work stressors on CHD risk is scarce. This study examines the separate and combined effect of job… Continue reading Psychosocial #Stressors at #Work and #Coronary Heart Disease Risk in Men and Women: 18-Year Prospective Cohort Study of Combined Exposures
Dietary #Carbohydrate and #Fat Intakes and Risk of Mortality in the Japanese Population: the Japan Multi-Institutional Collaborative Cohort Study
BackgroundPrevious cohort studies have yielded contradictory findings regarding the associations of dietary carbohydrate and fat intakes with risks of mortality.ObjectivesWe examined long-term associations of carbohydrate and fat intakes with mortality.MethodsIn this cohort study, 34,893 men and 46,440 women aged 35–69 y (mean body mass index of 23.7 and 22.2 kg/m2, respectively) were followed up from the baseline survey (2004–2014)… Continue reading Dietary #Carbohydrate and #Fat Intakes and Risk of Mortality in the Japanese Population: the Japan Multi-Institutional Collaborative Cohort Study
#Nicotinamide enhances natural #killer cell function and yields remissions in patients with non-Hodgkin #lymphoma
Administration of haploidentical donor natural killer (NK) cells, rituximab, and IL-2 to patients with non-Hodgkin lymphoma (NHL) has been shown to be safe, but the objective response rate was low, suggesting that further strategies to improve NK cell engraftment and function are needed. Here, Cichocki and colleagues showed that supplementation with nicotinamide during ex vivo… Continue reading #Nicotinamide enhances natural #killer cell function and yields remissions in patients with non-Hodgkin #lymphoma
Seated And Supine Blood #Pressure And Risk Of #Cardiovascular Disease And Mortality From The Atherosclerosis Risk In Communities Study
Background Hypertension (HTN) while asleep is strongly associated with cardiovascular disease (CVD) and death. Whether HTN while supine in clinic is a risk factor for CVD independent of seated BP remains unknown.Objectives To determine the relationship between supine HTN and adverse CVD.Methods The Atherosclerosis Risk in Communities (ARIC) Study measured supine and seated BP during visit 1 (1987-1989).… Continue reading Seated And Supine Blood #Pressure And Risk Of #Cardiovascular Disease And Mortality From The Atherosclerosis Risk In Communities Study
#Covid symptoms follow a very distinctive #pattern now – as common signs change, doctors discover
IN a short space of just a few years, the symptoms of Covid have changed in some surprising ways. Doctors are finding signs of the diseases are now following a very distinctive pattern. How Covid symptoms are changing thanks to heard immunity from prior infections and vaccines The illness’ past telltale signs, like the loss… Continue reading #Covid symptoms follow a very distinctive #pattern now – as common signs change, doctors discover
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