BackgroundDirect-acting oral anticoagulants (DOACs) have demonstrated superior efficacy in preventing stroke and death compared with warfarin in patients with atrial fibrillation (AF), but their influence on dementia risk remains unclear.ObjectivesThe purpose of this study was to evaluate the relative risks of dementia in DOAC vs warfarin in patients with AF.MethodsAn electronic literature search was conducted… Continue reading #Dementia Risk of Direct Oral Anticoagulants Versus Warfarin for Atrial #Fibrillation: Systematic Review and Meta-Analysis
Author: aledopress
Stress test abnormalities reveal more than just cardiovascular risks, Mayo Clinic study finds
The treadmill exercise test with electrocardiogram (ECG), also known as an exercise stress test, is one of the most familiar tests in medicine. While exercise testing typically is focused on diagnosing coronary artery disease, a recent study from Mayo Clinic finds that exercise test abnormalities, such as low functional aerobic capacity, predicted non-cardiovascular causes of death such as… Continue reading Stress test abnormalities reveal more than just cardiovascular risks, Mayo Clinic study finds
Assessment of Gastroesophageal #Reflux Symptoms and #Sleep Quality Among Women in the Nurses’ Health Study II
Limited data exist on the association of gastroesophageal reflux (GER) symptoms with sleep quality.Objective To prospectively investigate the association between GER symptoms and sleep quality.Design, Setting, and Participants This prospective cohort study included data from the Nurses’ Health Study II of female nurses in the US. Participants self-reported the frequency and duration of GER symptoms beginning June… Continue reading Assessment of Gastroesophageal #Reflux Symptoms and #Sleep Quality Among Women in the Nurses’ Health Study II
On this day … 16 September 1893
The Preston Chronicle carried a report from an angry meeting at Freckleton at which residents protested about ‘the abominable nuisance caused by the Preston Corporation and other public bodies bringing their sewage into the village’. The main target for the protests was Freckleton Farm. The sewage of both Preston and Fulwood was carried eight miles… Continue reading On this day … 16 September 1893
PRAC recommends new measures to avoid #topiramate exposure in #pregnancy
Further restrictions on use; pregnancy prevention programme to be put in placeEMA’s safety committee (PRAC) recommends new measures to avoid exposure of children to topiramate-containing medicines in the womb, because the medicine may increase the risk of neurodevelopmental problems after exposure during pregnancy. Topiramate is already known to cause serious birth defects when used during… Continue reading PRAC recommends new measures to avoid #topiramate exposure in #pregnancy
Viruses Beyond the Villains: The Incredible World of Beneficial Viruses
Scientists have estimated the presence of a staggering 10 nonillion (10^31) viruses on our planet, a number that surpasses stars in the universe by a factor of 100 million. While viruses are often synonymous with illness and harm, their immense diversity hints at a much more complex narrative. Yes, viruses possess the extraordinary capability to… Continue reading Viruses Beyond the Villains: The Incredible World of Beneficial Viruses
Risk of #Inflammatory #Bowel Disease in Patients With #Atopic Dermatitis
Data on the association between atopic dermatitis (AD) and inflammatory bowel disease (IBD) are inconsistent. Few studies have examined the association of AD or AD severity with risk of ulcerative colitis (UC) and Crohn disease (CD) separately.Objectives To examine the risk of new-onset IBD, UC, and CD in children and adults with AD. Design, Setting, and… Continue reading Risk of #Inflammatory #Bowel Disease in Patients With #Atopic Dermatitis
The AI Revolution in Medicine: GPT-4 and Beyond
The AI Revolution in Medicine: GPT-4 and Beyond by Peter Lee, Carey Goldberg, and Isaac Kohane This book was read for work, so it is clearly not the typical book that is reviewed on this blog. However, for anyone involved in data protection, data privacy, healthcare, clinical research, and/or artificial intelligence this book is a… Continue reading The AI Revolution in Medicine: GPT-4 and Beyond
Dietary #Carbohydrate and #Fat Intakes and Risk of #Mortality in the Japanese Population: the Japan Multi-Institutional Collaborative Cohort Study
BackgroundPrevious cohort studies have yielded contradictory findings regarding the associations of dietary carbohydrate and fat intakes with risks of mortality.ObjectivesWe examined long-term associations of carbohydrate and fat intakes with mortality.MethodsIn this cohort study, 34,893 men and 46,440 women aged 35–69 y (mean body mass index of 23.7 and 22.2 kg/m2, respectively) were followed up from the baseline survey (2004–2014)… Continue reading Dietary #Carbohydrate and #Fat Intakes and Risk of #Mortality in the Japanese Population: the Japan Multi-Institutional Collaborative Cohort Study