#IQ After Pediatric #Concussion

This study investigated IQ scores in pediatric concussion (ie, mild traumatic brain injury) versus orthopedic injury.METHODS:Children (N = 866; aged 8–16.99 years) were recruited for 2 prospective cohort studies from emergency departments at children’s hospitals (2 sites in the United States and 5 in Canada) ≤48 hours after sustaining a concussion or orthopedic injury. They completed… Continue reading #IQ After Pediatric #Concussion

Caffeine consumption as a risk factor for childhood and adolescence migraine

Background: Caffeine consumption is a risk factor for chronic daily headache but few studies have addressed relationships between pediatric patient caffeine levels and headache severity. We examined associations between serum and urine caffeine levels and headache severity in childhood and adolescent migraine cases.Methods: Levels of caffeine and caffeine metabolites in serum and urine samples were… Continue reading Caffeine consumption as a risk factor for childhood and adolescence migraine

Subclinical Coronary Atherosclerosis and Risk for Myocardial Infarction in a Danish CohortA Prospective Observational Cohort Study

Background:Coronary atherosclerosis may develop at an early age and remain latent for many years.Objective:To define characteristics of subclinical coronary atherosclerosis associated with the development of myocardial infarction.Design:Prospective observational cohort study.Setting:Copenhagen General Population Study, Denmark.Participants:9533 asymptomatic persons aged 40 years or older without known ischemic heart disease.Measurements:Subclinical coronary atherosclerosis was assessed with coronary computed tomography angiography… Continue reading Subclinical Coronary Atherosclerosis and Risk for Myocardial Infarction in a Danish CohortA Prospective Observational Cohort Study

Elevated Blood Pressure and Worsening Cardiac Damage During Adolescence

ObjectivesTo examine the longitudinal course for the development of elevated blood pressure (BP)/hypertension and cardiac damage in adolescents.Study designFrom the Avon Longitudinal Study of Parents and Children, UK birth cohort, 1856 (1011 females) 17-year-olds were followed-up for 7 years. BP and echocardiography were assessed at ages 17 and 24 years. Elevated/hypertensive BP was defined as… Continue reading Elevated Blood Pressure and Worsening Cardiac Damage During Adolescence

COVID-19 vaccine boosters for young adults: a risk benefit assessment and ethical analysis of mandate policies at universities 

In 2022, students at North American universities with third-dose COVID-19 vaccine mandates risk disenrolment if unvaccinated. To assess the appropriateness of booster mandates in this age group, we combine empirical risk-benefit assessment and ethical analysis. To prevent one COVID-19 hospitalisation over a 6-month period, we estimate that 31 207–42 836 young adults aged 18–29 years must receive… Continue reading COVID-19 vaccine boosters for young adults: a risk benefit assessment and ethical analysis of mandate policies at universities 

Increased emergency cardiovascular events among under-40 population in Israel during vaccine rollout and third COVID-19 wave

Cardiovascular adverse conditions are caused by coronavirus disease 2019 (COVID-19) infections and reported as side-effects of the COVID-19 vaccines. Enriching current vaccine safety surveillance systems with additional data sources may improve the understanding of COVID-19 vaccine safety. Using a unique dataset from Israel National Emergency Medical Services (EMS) from 2019 to 2021, the study aims… Continue reading Increased emergency cardiovascular events among under-40 population in Israel during vaccine rollout and third COVID-19 wave

Deaths in Children and #Young People in England following #SARS-CoV-2 infection during the first pandemic year: a national study using linked mandatory child death reporting data

This is a preprint. It has not completed peer review. Background Deaths in children and young people (CYP) following SARS-CoV-2 infection are rare. Quantifying the risk of mortality is challenging because of high relative prevalence of asymptomatic and non-specific disease manifestations. Therefore, it is important to differentiate between CYP who have died of SARS-CoV-2 and… Continue reading Deaths in Children and #Young People in England following #SARS-CoV-2 infection during the first pandemic year: a national study using linked mandatory child death reporting data

Prevalence of #Prediabetes Among #Adolescents and Young Adults in the United States, 2005-2016

.. Impaired fasting glucose was defined as fasting plasma glucose of 100 mg/dL to less than 126 mg/dL, IGT as 2-hour plasma glucose of 140 mg/dL to less than 200 mg/dL, and increased HbA1c level as HbA1c level between 5.7% and 6.4%. The prevalence of IFG, isolated IFG, IGT, isolated IGT, increased HbA1c level, isolated… Continue reading Prevalence of #Prediabetes Among #Adolescents and Young Adults in the United States, 2005-2016

Death rates due to #Suicide or #Homicide Among persons aged 10-24 : United States 2000-2017

Key findings Data from the National Vital Statistics System After stable trends from 2000 to 2007, suicide rates for persons aged 10–24 increased from 2007 (6.8 per 100,000 persons) to 2017 (10.6), while homicide rates declined from 2007 to 2014 and then increased through 2017. The suicide rate for persons aged 10–14 declined from 2000… Continue reading Death rates due to #Suicide or #Homicide Among persons aged 10-24 : United States 2000-2017