Vital statistics are the primary source of data used to understand the mortality burden of dementia in the US, despite evidence that dementia is underreported on death certificates. Alternative estimates, drawing on population-based samples, are needed ..Of the 7342 total sample, 4348 participants (60.3%) were women. At baseline, 4533 individuals (64.0%) were between ages 70… Continue reading Estimates of the Association of #Dementia With US #Mortality Levels Using Linked Survey and Mortality Records
Tag: mortality
Statin adherence and risk of all-cause, cancer, and cardiovascular mortality among dyslipidemia patients: A time-dependent analysis
Results have been mixed and uncertainty still remains regarding the impact of statin adherence on premature deaths. Thus, we investigated the association between statin adherence and risks of all-cause, cancer, and cardiovascular mortality among dyslipidemia patients in South Korea.. We used data from the National Health Insurance Service (NHIS) National Sample Cohort for the years… Continue reading Statin adherence and risk of all-cause, cancer, and cardiovascular mortality among dyslipidemia patients: A time-dependent analysis
#Dexamethasone in Hospitalized Patients with #Covid-19 — Preliminary Report
Coronavirus disease 2019 (Covid-19) is associated with diffuse lung damage. Glucocorticoids may modulate inflammation-mediated lung injury and thereby reduce progression to respiratory failure and death In this controlled, open-label trial comparing a range of possible treatments in patients who were hospitalized with Covid-19, we randomly assigned patients to receive oral or intravenous dexamethasone (at a… Continue reading #Dexamethasone in Hospitalized Patients with #Covid-19 — Preliminary Report
Association between #prediabetes and risk of all cause mortality and #cardiovascular disease: updated meta-analysis
To evaluate the associations between prediabetes and the risk of all cause mortality and incident cardiovascular disease in the general population and in patients with a history of atherosclerotic cardiovascular disease.. ..A total of 129 studies were included, involving 10 069 955 individuals for analysis. In the general population, prediabetes was associated with an increased risk of… Continue reading Association between #prediabetes and risk of all cause mortality and #cardiovascular disease: updated meta-analysis
Association of Rapid Eye Movement #Sleep With Mortality in Middle-aged and Older Adults
Rapid eye movement (#REM) sleep has been linked with health outcomes, but little is known about the relationship between REM sleep and mortality.. ..The MrOS cohort included 2675 individuals (2675 men [100%]; mean [SD] age, 76.3 [5.5] years) and was followed up for a median (interquartile range) of 12.1 (7.8-13.2) years. The WSC cohort included 1386… Continue reading Association of Rapid Eye Movement #Sleep With Mortality in Middle-aged and Older Adults
Association of Statin Use With All-Cause and Cardiovascular Mortality in US Veterans 75 Years and Older
Data are limited regarding statin therapy for primary prevention of atherosclerotic cardiovascular disease (ASCVD) in adults 75 years and older.. ..Of 326 981 eligible veterans (mean [SD] age, 81.1 [4.1] years; 97% men; 91% white), 57 178 (17.5%) newly initiated statins during the study period. During a mean follow-up of 6.8 (SD, 3.9) years, a total 206 902… Continue reading Association of Statin Use With All-Cause and Cardiovascular Mortality in US Veterans 75 Years and Older
Association of Azithromycin Use With Cardiovascular Mortality
Azithromycin is one of the most commonly prescribed antibiotics in the US. It has been associated with an increased risk of cardiovascular death in some observational studies.. ..The study included 7 824 681 antibiotic exposures, including 1 736 976 azithromycin exposures (22.2%) and 6 087 705 amoxicillin exposures (77.8%), among 2 929 008 unique individuals (mean [SD] age, 50.7 [12.3] years; 1 810 127 [61.8%]… Continue reading Association of Azithromycin Use With Cardiovascular Mortality
Antihypertensive Treatment in Elderly Frail Patients Evidence From a Large Italian Database
Aim of our study was to assess the relationship between adherence with antihypertensive drugs and the risk of death in frail versus nonfrail old individuals. Using the database of the Lombardy Region (Italy), we identified 1 283 602 residents aged ≥65 years (mean age 76) who had ≥3 prescriptions of antihypertensive drugs between 2011 and… Continue reading Antihypertensive Treatment in Elderly Frail Patients Evidence From a Large Italian Database
Dose-Response Association of Low-Intensity and Nondaily Smoking With Mortality in the United States
An increasing proportion of US smokers smoke at low intensity and not every day. Some nondaily smokers have always had this pattern, whereas others previously smoked daily. The effect of reducing the level of smoking from daily to nondaily smoking and the dose response at low smoking levels are poorly understood.. ..Among 505 500 participants (aged… Continue reading Dose-Response Association of Low-Intensity and Nondaily Smoking With Mortality in the United States
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