AbstractWe evaluated the effect of diets low in energy density (1 kcal/g) and high in either potatoes (Potato) or pulses (Bean) on blood glucose control in participants with insulin resistance. We hypothesized that the Potato and Bean diets would have equivalent effects. This was an 8-week randomized, parallel design, controlled feeding study comparing Potato and… Continue reading Low-Energy Dense Potato- and Bean-Based Diets Reduce Body Weight and Insulin Resistance: A Randomized, Feeding, Equivalence Trial
Tag: Diabetes
Psychological resilience in older adults with type 2 diabetes from the Look AHEAD Trial
BackgroundThere is growing interest in identifying factors associated with healthy aging. This cross-sectional study evaluated associations of psychological resilience with factors associated with aging in older adults with type 2 diabetes mellitus (T2DM).MethodsParticipants were 3199 adults (72.2 ± 6.2 years of age, 61% female, 61% White, body mass index [BMI] = 34.2 ± 8.2 kg/m2) with T2DM enrolled in Look AHEAD (a multi-site… Continue reading Psychological resilience in older adults with type 2 diabetes from the Look AHEAD Trial
Weight loss strategies, weight change, and type 2 diabetes in US health professionals: A cohort study
BackgroundWeight loss is crucial for disease prevention among individuals with overweight or obesity. This study aimed to examine associations of weight loss strategies (WLSs) with weight change and type 2 diabetes (T2D) risk among US health professionals.Methods and findingsThis study included 93,110 participants (24 to 60 years old; 11.6% male) from the Nurses’ Health Study… Continue reading Weight loss strategies, weight change, and type 2 diabetes in US health professionals: A cohort study
Diabetes and Obesity in Down Syndrome Across the Lifespan: A Retrospective Cohort Study Using U.K. Electronic Health Records
Down syndrome (DS) is the most common form of chromosomal trisomy. Genetic factors in DS may increase the risk for diabetes. This study aimed to determine whether DS is associated with an increased incidence of diabetes and the relationship with obesity across the life span compared with control patients.RESEARCH DESIGN AND METHODSThis matched population–based cohort… Continue reading Diabetes and Obesity in Down Syndrome Across the Lifespan: A Retrospective Cohort Study Using U.K. Electronic Health Records
Modifiable risk factors and long term risk of type 2 diabetes among individuals with a history of gestational diabetes mellitus: prospective cohort study
Objectives To evaluate the individual and combined associations of five modifiable risk factors with risk of type 2 diabetes among women with a history of gestational diabetes mellitus and examine whether these associations differ by obesity and genetic predisposition to type 2 diabetesSetting Nurses’ Health Study II, US.Participants 4275 women with a history of gestational diabetes mellitus, with… Continue reading Modifiable risk factors and long term risk of type 2 diabetes among individuals with a history of gestational diabetes mellitus: prospective cohort study
Association of Combined Healthy Lifestyle Factors With Incident Dementia in Patients With Type 2 Diabetes
Background and Objectives: Type 2 diabetes and lifestyle factors have been associated with dementia risk, but the impact of a healthy lifestyle on diabetes-related dementia remains largely unknown. We aimed to investigate whether the increased risk of dementia among individuals with diabetes can be offset by a broad combination of healthy lifestyle factors.Methods: This prospective study utilized… Continue reading Association of Combined Healthy Lifestyle Factors With Incident Dementia in Patients With Type 2 Diabetes
Inhibition of pancreatic EZH2 restores progenitor insulin in T1D donor
Type 1 diabetes (T1D) is an autoimmune disease that selectively destroys insulin-producing β-cells in the pancreas. An unmet need in diabetes management, current therapy is focussed on transplantation. While the reprogramming of progenitor cells into functional insulin-producing β-cells has also been proposed this remains controversial and poorly understood. The challenge is determining why default transcriptional… Continue reading Inhibition of pancreatic EZH2 restores progenitor insulin in T1D donor
Incidence of New-Onset Type 2 Diabetes After Cancer: A Danish Cohort Study
For patients with cancer, prevalent type 2 diabetes at the date of cancer diagnosis is associated with increased cancer-specific and all-cause mortality (1,2). Yet, despite potential health implications, there is limited knowledge on whether cancer is also a risk factor for type 2 diabetes. Moreover, the impact of new-onset type 2 diabetes after cancer diagnosis… Continue reading Incidence of New-Onset Type 2 Diabetes After Cancer: A Danish Cohort Study
Effect of active vitamin D treatment on development of type 2 diabetes: DPVD randomised controlled trial in Japanese population
To assess whether eldecalcitol, an active vitamin D analogue2, can reduce the development of type 2 diabetes among adults with impaired glucose tolerance. Design Double blinded, multicentre, randomised, placebo controlled trial. Setting Three hospitals in Japan, between June 2013 and August 2019. Participants People aged 30 years and older who had impaired glucose tolerance defined… Continue reading Effect of active vitamin D treatment on development of type 2 diabetes: DPVD randomised controlled trial in Japanese population
2 Medical News 